nystatin-a1 and Cryptococcosis

nystatin-a1 has been researched along with Cryptococcosis* in 15 studies

Reviews

5 review(s) available for nystatin-a1 and Cryptococcosis

ArticleYear
[Prevention and treatment of invasive mycoses in patients with neutropenia and bone marrow transplantation].
    Revista clinica espanola, 1995, Volume: 195 Suppl 3

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Bone Marrow Transplantation; Candidiasis; Candidiasis, Chronic Mucocutaneous; Clinical Trials as Topic; Cryptococcosis; Double-Blind Method; Fluconazole; Humans; Itraconazole; Ketoconazole; Mucormycosis; Mycoses; Neutropenia; Nystatin; Primary Prevention; Recurrence; Retrospective Studies

1995
Antifungal drugs.
    The Journal of antimicrobial chemotherapy, 1975, Volume: 1, Issue:2

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Blastomycosis; Candicidin; Candidiasis; Coccidioidomycosis; Colistin; Cryptococcosis; Dermatomycoses; Drug Resistance, Microbial; Emetine; Flucytosine; Griseofulvin; Histoplasmosis; Humans; Imidazoles; Minocycline; Natamycin; Nystatin; Polyenes; Tolnaftate

1975
[Ocular mycoses].
    Bulletin de la Societe belge d'ophtalmologie, 1968, Volume: 148

    Topics: Actinomycosis; Adolescent; Adult; Amphotericin B; Animals; Aspergillosis; Basidiomycota; Blastomycosis; Candidiasis; Cephalosporins; Child; Chromoblastomycosis; Coccidioidomycosis; Conjunctiva; Cryptococcosis; Drug Synergism; Eye Diseases; Female; Fungi; Geotrichosis; Guinea Pigs; Histoplasmosis; Humans; Male; Mucor; Mycetoma; Mycoses; Natamycin; Nystatin; Penicillium; Pityriasis; Rabbits; Rhinosporidiosis; Sporotrichosis; Tinea

1968
[THERAPY OF CANDIDOSIS].
    La Clinica terapeutica, 1964, Feb-15, Volume: 28

    Topics: Actinomycosis; Amphotericin B; Anti-Bacterial Agents; Aspergillosis; Candidiasis; Cryptococcosis; Griseofulvin; Histoplasmosis; Humans; Nystatin; Penicillins

1964
SYSTEMIC FUNGAL INFECTIONS AMENABLE TO CHEMOTHERAPY
    Disease-a-month : DM, 1963, Volume: 35

    Topics: Actinomycosis; Amphotericin B; Anti-Bacterial Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidomycosis; Cryptococcosis; Griseofulvin; Histoplasmosis; Humans; Iodides; Mucormycosis; Mycoses; Nocardia Infections; Nystatin; Penicillins; Sporotrichosis; Stilbamidines; Sulfadiazine; Surgical Procedures, Operative; Toxicology

1963

Other Studies

10 other study(ies) available for nystatin-a1 and Cryptococcosis

ArticleYear
Immune stimulating and therapeutic potential of tuftsin-incorporated nystatin liposomes against Cryptococcus neoformans in leukopenic BALB/C mice.
    FEMS immunology and medical microbiology, 2012, Volume: 66, Issue:1

    Cryptococcus neoformans infection is a common fungal infection in persons infected with human immune deficiency virus (HIV) or those with defective cell-mediated immunity. Since treatment of cryptococcal meningitis poses a big challenge, the present study aimed to develop a novel liposomal therapeutic formulation against cryptococcosis. Treatment with tuftsin-incorporated liposomes increased the anti-cryptococcal activity of murine peritoneal macrophages. Prophylactic treatment of mice with tuftsin-incorporated liposomes reduced the dissemination of C. neoformans to brain tissues. Moreover, the co-administration of tuftsin with nystatin liposomes augmented the anti-cryptococcal activity of nystatin, as mice treated with tuftsin-incorporated nystatin liposomes showed the highest survival and least fungal burden in their brain tissues. The results of the present study favour the use of immune-stimulating molecules along with antifungal agents in the treatment of opportunistic fungal infections.

    Topics: Animals; Antifungal Agents; Brain; Cells, Cultured; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Immunologic Factors; Liposomes; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nystatin; Survival Analysis; Treatment Outcome; Tuftsin

2012
Enhanced efficacy of pH-sensitive nystatin liposomes against Cryptococcus neoformans in murine model.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:2

    To evaluate the efficacy of pH-sensitive liposomes of nystatin against Cryptococcus neoformans infection in a murine model.. In the present study, we investigated the antifungal activity of nystatin entrapped in pH-sensitive liposomes in a murine model. Mice infected with C. neoformans were treated with nystatin in neutral egg phosphatidylcholine (egg-PC) liposomes, as well as pH-sensitive nystatin liposomes. The anticryptococcal efficacy of liposomal formulations of nystatin was assessed by continued survival and colony-forming units (cfu) in liver and brain of the treated mice.. pH-sensitive liposomes of nystatin showed better efficacy compared with its free or egg-PC liposome form against C. neoformans infection in BALB/c mice. Mice treated with pH-sensitive nystatin liposomes showed 80% survival with less fungal burden in liver and brain of treated mice. However, there was only 40% survival in the group of animals treated with egg-PC liposome-intercalated nystatin, whereas its free form had poor efficacy with 20% survival.. The enhanced anticryptococcal efficacy of the pH-sensitive nystatin liposomes can be attributed to the pH-dependent release of the drug in the low pH environment of lysosomes. The destabilization of the pH-sensitive liposomes in the acidic environment of macrophages results in the site-specific targeting of nystatin that improves its intracellular antifungal activity.

    Topics: Animals; Antifungal Agents; Brain; Cryptococcosis; Drug Carriers; Hydrogen-Ion Concentration; Intercalating Agents; Liposomes; Liver; Male; Mice; Mice, Inbred BALB C; Nystatin; Phosphatidylcholines; Survival Analysis

2006
[Iatrogenic mycoses with deep visceral localization caused by opportunistic fungi].
    Dermatologica, 1979, Volume: 159, Issue:Suppl 1

    The new therapeutic methods based on antibiotics, corticosteroids and immunosuppressors and the new medicosurgical techniques (catheters, monitoring in intensive-care units, open-heart surgery) modify the host, favorise the adaptation and introduction f endogenous and exogenous yeast-like fungi and thus create a new pathology characterized by deep visceral or septicemic infections due to yeasts belonging to the genera Candida, Torulopsis, Cryptococcus, Trichosporon, Rhodotorula, and Saccharomyces. The pathological aspects are analyzed and therapy is suggested in the light of new findings on polyenes (nystatine, amphotericine B), 5-fluorocytosine, imidazole, derivatives (miconazole, econazole) considering their association in function of synergy or antagonism possibilities.

    Topics: Amphotericin B; Candida; Candidiasis; Cryptococcosis; Dermatomycoses; Endocarditis; Flucytosine; Humans; Iatrogenic Disease; Imidazoles; Lung Diseases, Fungal; Mycoses; Nystatin; Osteitis; Sepsis; Urinary Tract Infections

1979
Vaccine and Mycostatin in treatment of cryptococcosis of the respiratory tract.
    Sabouraudia, 1976, Volume: 14, Issue:2

    Three cases of respiratory crytococcosis are described, one diagnosed only after thoracotomy and two after cytology. All were confirmed by cultures, biological and biochemical tests. The patients are alive and well 14 years, 5 years, and 5 years after treatment with crytococcal vaccines and mycostatin. Vaccines proved very effective when given intradermally in small doses and no dangerous reactions were encountered. Cytology of the sputum appears to be a very useful tool in diagnosis of fungal infections of the respiratory tract, especially when supravital staining is used. Difficulties in diagnosis, treatment, and significance of positive sputum findings are discussed.

    Topics: Adult; Aged; Bronchitis; Candida albicans; Candidiasis; Cryptococcosis; Cryptococcus; Cryptococcus neoformans; Fungal Vaccines; Humans; Lung Diseases, Fungal; Middle Aged; Nystatin; Respiratory Tract Infections

1976
Treatment of systemic mycoses.
    Medicine, 1973, Volume: 52, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidomycosis; Cryptococcosis; Flucytosine; Histoplasmosis; Humans; Iodides; Mycoses; Nystatin; Sporotrichosis

1973
Diagnosis and therapy of systemic mycoses in the immunosuppressed host.
    Transplantation proceedings, 1973, Volume: 5, Issue:3

    Topics: Agranulocytosis; Amphotericin B; Antineoplastic Agents; Aspergillosis; Candidiasis; Cryptococcosis; Cytosine; Diabetes Complications; Glucocorticoids; Humans; Immunosuppression Therapy; Mucormycosis; Mycoses; Nystatin

1973
[Pulmonary cryptoccosis cured with endobronchial treatment].
    Giornale di gerontologia, 1971, Volume: 19, Issue:5

    Topics: Aerosols; Aged; Amphotericin B; Bronchi; Cryptococcosis; Humans; Lung Diseases, Fungal; Male; Nystatin

1971
Diagnosis of surgical deep mycoses.
    Surgery, gynecology & obstetrics, 1969, Volume: 128, Issue:2

    Topics: Actinomycosis; Adult; Amphotericin B; Biopsy; Blastomycosis; Coccidioidomycosis; Cryptococcosis; Diagnosis, Differential; Female; Histoplasmosis; Humans; Male; Middle Aged; Mycoses; Nystatin; Respiratory Tract Infections; Skin; Skin Diseases; Skin Ulcer; South America; Sputum

1969
[Advances in the therapy of mycoses].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1967, Volume: 18, Issue:7

    Topics: Actinomycosis; Adult; Amphotericin B; Aspergillosis; Blastomycosis; Candidiasis, Vulvovaginal; Child; Cryptococcosis; Dermatomycoses; Female; Griseofulvin; Humans; Lung Diseases, Fungal; Mycetoma; Mycoses; Nails; Nocardia Infections; Nystatin; Skin Diseases; Sporotrichosis; Stilbamidines; Thallium; Tinea Pedis

1967
[Case contribution on the clinical picture of torulosis].
    Zeitschrift fur Tuberkulose und Erkrankungen der Thoraxorgane, 1967, Volume: 126, Issue:5

    Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococcus; Diagnosis, Differential; Humans; Male; Nystatin

1967