nylidrin has been researched along with Pregnancy in 46 studies
Nylidrin: A beta-adrenergic agonist. Nylidrin causes peripheral vasodilation, a positive inotropic effect, and increased gastric volume of gastric juice. It is used in the treatment of peripheral vascular disorders and premature labor.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty pregnant women threatened with preterm labor between 24 and 34 weeks of gestation were enrolled in the study." | 6.67 | Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor. ( Eronen, M; Hallman, M; Kurki, T; Pesonen, E; Teramo, K; Ylikorkala, O, 1994) |
| "Forty-eight patients hospitalised for EPH gestosis were treated for hypertension, using one constant dosage of Dilatol tablets." | 5.26 | [Effects of nylidrine (Dilatol) on blood pressure of hypertensive patients in advanced pregnancy (author's transl)]. ( During, R; Mauck, I, 1980) |
| " Taking a minimum birth weight of 2500 g as the criteria of successful treatment, the success rate in the placebo group was 71%, in the Nylidrin hydrochloride group 86%, the Isoxuprine hydrochloride group 75% and the alcohol group 70%." | 5.04 | Treatment of imminent premature labour. ( Castrén, O; Gummerus, M; Saarikoski, S, 1975) |
| "The effects of one single intravenous injection of 5 mg of nylidrin, following administration of 113m-indium, on utero-placental blood supply were studied in 23 women in advanced pregnancy, all of them afflicted with hypertension." | 3.66 | [Action of nylidrin (Dilatol) on utero-placental blood supply (author's transl)]. ( During, R; Reincke, R, 1981) |
| "Dilatol (Nylidrin), a betamimetic used for tocolysis, was applied to ten hypertensive women in advanced pregnancy and produced in them characteristic effects with favourable impact upon oxygen supply to the foetuses, such as significant lowering of diastolic pressure, decrease in total peripheral resistance which reflected increase in uteroplacental blood flow, as well as rises in heart rate, stroke volume, and cardiac output." | 3.66 | [Dilatol for hypertension therapy in pregnancy (author's transl)]. ( During, R; Lauckner, W; Retzke, U; Schwarz, R, 1979) |
| "Eighty pregnant women threatened with preterm labor between 24 and 34 weeks of gestation were enrolled in the study." | 2.67 | Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor. ( Eronen, M; Hallman, M; Kurki, T; Pesonen, E; Teramo, K; Ylikorkala, O, 1994) |
| "Nylidrin treatment was accompanied by a 35% rise in COMT activity 3 h later, whereas indomethacin caused no significant change." | 2.67 | Catechol-O-methyltransferase activity in red blood cells in threatened preterm labor; effect of indomethacin and nylidrin. ( Kurki, T; Lindén, IB; Schultz, E; Ylikorkala, O, 1991) |
| "Indomethacin treatment was accompanied by maternal side effects 20% of the time, significantly less commonly (P less than ." | 2.67 | A randomized double-dummy comparison between indomethacin and nylidrin in threatened preterm labor. ( Eronen, M; Kurki, T; Lumme, R; Ylikorkala, O, 1991) |
| "One hundred and seventy patients with threatened abortion have been studied in two groups." | 2.66 | Buphenine and threatened abortion. ( Soltan, MH, 1986) |
| "Thirty-three women in preterm labor between 25 and 34 weeks of gestation were studied before, during, and after treatment with indomethacin (n = 16) or nylidrin (n = 17)." | 1.28 | Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin. ( Kurki, T; Viinikka, L; Ylikorkala, O, 1992) |
| "A case of pulmonary edema during tocolytic therapy with beta-mimetic drugs is demonstrated." | 1.27 | [Pulmonary edema under tocolytic therapy]. ( Schöpfel, W; Schreiber, E, 1985) |
| "Forty-eight patients hospitalised for EPH gestosis were treated for hypertension, using one constant dosage of Dilatol tablets." | 1.26 | [Effects of nylidrine (Dilatol) on blood pressure of hypertensive patients in advanced pregnancy (author's transl)]. ( During, R; Mauck, I, 1980) |
| "For prevention of premature labor the betasympathicomimetic drugs buphenin, fenoterol, and ritodrine were administered to 135 patients intravenously for 1 week and afterward orally up to the end of week 37 of gestation." | 1.26 | Evaluation of success in treatment of threatening premature labor by betamimetic drugs. ( Richter, R, 1977) |
| "A twin pregnancy is reported in which a prolonged interval between delivery of twins was accomplished by the use of labor-inhibiting drugs and the placement of a cerevical cerclage." | 1.26 | Delayed interval delivery of a twin pregnancy. ( Thomsen, RJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (80.43) | 18.7374 |
| 1990's | 9 (19.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolff, F | 1 |
| Bolte, A | 1 |
| Berg, R | 1 |
| Lenczewski, A | 2 |
| Jaworski, S | 2 |
| Lotocki, W | 2 |
| Bielecki, M | 2 |
| Lazewska, M | 2 |
| During, R | 3 |
| Reincke, R | 1 |
| Mauck, I | 1 |
| Eronen, M | 5 |
| Pesonen, E | 2 |
| Kurki, T | 6 |
| Teramo, K | 1 |
| Ylikorkala, O | 6 |
| Hallman, M | 2 |
| Salokorpi, T | 1 |
| von Wendt, L | 1 |
| Neubüser, D | 2 |
| Richter, R | 3 |
| Bollmann, R | 2 |
| Halle, H | 3 |
| Tschoep, M | 1 |
| Hofer, U | 2 |
| Ammann, K | 1 |
| Kuć, A | 1 |
| Skrzydlewski, Z | 1 |
| Retzke, U | 2 |
| Schwarz, R | 2 |
| Lauckner, W | 1 |
| Eggimann, UH | 1 |
| Thürig, E | 1 |
| Moser, H | 1 |
| Bossi, E | 1 |
| Gerner, R | 1 |
| Halberstadt, E | 1 |
| Schwarz, H | 1 |
| Stein, WW | 1 |
| Thomsen, RJ | 1 |
| Bayer, H | 1 |
| Issel, EP | 1 |
| Hengst, P | 1 |
| Prenzlau, P | 1 |
| Barten, G | 1 |
| Castrén, O | 3 |
| Gummerus, M | 3 |
| Saarikoski, S | 3 |
| Müller, K | 1 |
| Hammacher, K | 1 |
| Hinselmann, M | 1 |
| Viinikka, L | 1 |
| Laatikainen, T | 1 |
| Salminen-Lappalainen, K | 1 |
| Schultz, E | 1 |
| Lindén, IB | 1 |
| Lumme, R | 1 |
| Santala, M | 1 |
| Soltan, MH | 1 |
| Schreiber, E | 1 |
| Schöpfel, W | 1 |
| Lorenz, D | 1 |
| Thompson, O | 1 |
| Hüter, J | 1 |
| Lammers, G | 1 |
| Mosler, KH | 1 |
| Dornhöfer, W | 1 |
| Linka, F | 1 |
| Koepcke, E | 2 |
| Seidenschnur, G | 2 |
| Hauschild, R | 2 |
| Seewald, HJ | 2 |
| Jürgens, H | 1 |
| Köppe, I | 1 |
| Räber, G | 1 |
| Dücker, R | 1 |
| Fischer, WM | 1 |
| Thomsen, K | 1 |
| Schröder, H | 1 |
| Soiva, K | 1 |
| Zorn, C | 1 |
| Ittrich, G | 1 |
| Scholtes, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Placebo Controlled Trial of Indomethacin for Tocolysis[NCT01869361] | Early Phase 1 | 0 participants (Actual) | Interventional | 2020-08-01 | Withdrawn (stopped due to Due to much lower than expected numbers of eligible patients and lack of PI time, the study was not started.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nylidrin and Pregnancy
| Article | Year |
|---|---|
[Clinical use of labor inhibiting substances].
Topics: Amino Alcohols; Female; Germany, East; Humans; Infant Mortality; Nylidrin; Obstetric Labor, Prematur | 1973 |
9 trials available for nylidrin and Pregnancy
| Article | Year |
|---|---|
Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor.
Topics: Adult; Bronchopulmonary Dysplasia; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; | 1994 |
The hemodynamic effects of antenatal indomethacin and a beta-sympathomimetic agent on the fetus and the newborn: a randomized study.
Topics: Adult; Blood Flow Velocity; Ductus Arteriosus, Patent; Female; Fetal Diseases; Fetus; Gestational Ag | 1993 |
Growth and development until 18 months of children exposed to tocolytics indomethacin or nylidrin.
Topics: Child Development; Female; Follow-Up Studies; Growth; Humans; Indomethacin; Infant, Newborn; Infant, | 1996 |
Treatment of imminent premature labour.
Topics: Birth Weight; Clinical Trials as Topic; Ethanol; Female; Follow-Up Studies; Gestational Age; Humans; | 1975 |
Catechol-O-methyltransferase activity in red blood cells in threatened preterm labor; effect of indomethacin and nylidrin.
Topics: Adult; Catechol O-Methyltransferase; Double-Blind Method; Erythrocytes; Female; Humans; Indomethacin | 1991 |
A randomized double-dummy comparison between indomethacin and nylidrin in threatened preterm labor.
Topics: Adult; Double-Blind Method; Female; Humans; Indomethacin; Nylidrin; Obstetric Labor, Premature; Preg | 1991 |
The effects of indomethacin and a beta-sympathomimetic agent on the fetal ductus arteriosus during treatment of premature labor: a randomized double-blind study.
Topics: Blood Flow Velocity; Cardiac Output, Low; Delivery, Obstetric; Double-Blind Method; Ductus Arteriosu | 1991 |
Buphenine and threatened abortion.
Topics: Abortion, Threatened; Adolescent; Adult; Female; Humans; Nylidrin; Placebos; Pregnancy | 1986 |
[Analysis of the maternal and fetal heart frequency after administration of direct and indirect sympathomimetic agents].
Topics: Blood Pressure; Body Height; Body Weight; Clinical Trials as Topic; Computers; Electrocardiography; | 1972 |
36 other studies available for nylidrin and Pregnancy
| Article | Year |
|---|---|
[Does an additional administration of acetylsalicylic acid reduce the requirement of betamimetics in tocolytic treatment? (author's transl)].
Topics: Adrenergic beta-Agonists; Aspirin; Cervix Uteri; Drug Therapy, Combination; Ethanolamines; Female; F | 1981 |
[Effect of bufenine hydrochloride on circulating blood volume and physical development of fetuses of female rabbits with experimental hypertension].
Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Blood Volume; Female; Fetus; Growth; Hyp | 1983 |
[Morphological studies of the pulmonary arterioles in pregnant rabbits with experimental hypertension after administration of dilatol].
Topics: Animals; Antihypertensive Agents; Arteries; Arterioles; Female; Hypertension; Lung; Nylidrin; Pregna | 1984 |
[Action of nylidrin (Dilatol) on utero-placental blood supply (author's transl)].
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; Maternal-Fetal Exchange; Nylidrin; Pregnancy; P | 1981 |
[Effects of nylidrine (Dilatol) on blood pressure of hypertensive patients in advanced pregnancy (author's transl)].
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; Nylidrin; Pre-Eclampsia; Pregnancy; Pregnancy C | 1980 |
[The influence of partusisten and dilatol on the amino-acid metabolism (author's transl)].
Topics: Administration, Oral; Adrenergic beta-Agonists; Amino Acids; Ethanolamines; Female; Fenoterol; Glyco | 1976 |
Evaluation of success in treatment of threatening premature labor by betamimetic drugs.
Topics: Adrenergic beta-Agonists; Female; Fenoterol; Gestational Age; Humans; Infant, Newborn; Nylidrin; Obs | 1977 |
[Effects of beta-sympathicomimetics on ionogram, transaminases, and ECG in pregnancy (author's transl)].
Topics: Abortion, Therapeutic; Abortion, Threatened; Adrenergic beta-Agonists; Drug Evaluation; Electrocardi | 1979 |
[The oral tocolytic long time therapy and its effects on the child (author's transl)].
Topics: Female; Glucose; Humans; Infant, Newborn; Long-Term Care; Maternal-Fetal Exchange; Nylidrin; Obstetr | 1978 |
[Effectiveness of prolonged uterine relaxation by betamimetic drugs for threatened premature labour (author's transl)].
Topics: Ethanolamines; Female; Fenoterol; Gestational Age; Humans; Infant Mortality; Long-Term Care; Nylidri | 1978 |
[Lipids in pregnant patients with severe course of gestosis treated with xanthinol nicotinate and bufenin hydrochloride].
Topics: Cholesterol; Female; Humans; Lipids; Lipoproteins, LDL; Nylidrin; Pre-Eclampsia; Pregnancy; Theophyl | 1976 |
[Dilatol for hypertension therapy in pregnancy (author's transl)].
Topics: Adult; Drug Evaluation; Female; Humans; Hypertension; Labor, Induced; Nylidrin; Pregnancy; Pregnancy | 1979 |
[Threatened abortion: patient characteristics, treatment results and consequences for the child].
Topics: Abortion, Threatened; Congenital Abnormalities; Diazepam; Dydrogesterone; Female; Hexestrol; Humans; | 1979 |
[The effect of labor-inhibiting agents on phospholipid synthesis in the fetal lung (proceedings)].
Topics: Animals; Ethanolamines; Female; Fenoterol; Lung; Nylidrin; Phosphatidylcholines; Pregnancy; Rats | 1977 |
Delayed interval delivery of a twin pregnancy.
Topics: Adult; Cervix Uteri; Delivery, Obstetric; Female; Fenoterol; Gestational Age; Humans; Infant, Newbor | 1978 |
[Clinical problems of premature labor. 2. Therapy of threatening and actual premature labor].
Topics: Diazepam; Female; Humans; Nylidrin; Obstetric Labor, Premature; Phenobarbital; Pregnancy; Ritodrine; | 1976 |
[Cardiovascular effects of nylidrin (Dilatol) in pregnancy].
Topics: Adult; Blood Pressure; Cardiovascular System; Female; Heart Rate; Hemodynamics; Humans; Labor, Obste | 1976 |
[Prevention of premature birth with nylidrin and verapamil (author's transl)].
Topics: Birth Weight; Female; Humans; Infant, Newborn; Injections, Intravenous; Nylidrin; Obstetric Labor, P | 1975 |
[Clinical experience with Dilatol therapy in EPH-gestoses].
Topics: Blood Pressure; Drug Evaluation; Female; Fetus; Humans; Infant, Newborn; Nylidrin; Pre-Eclampsia; Pr | 1975 |
[Proceedings: Prophylaxis of threatened premature labor. Clinical results in a prospective comparative study with ritodrine and buphenine].
Topics: Female; Humans; Nylidrin; Obstetric Labor, Premature; Pregnancy; Propanolamines; Ritodrine | 1975 |
[Long term use of buphenin-hchl (Dilydrin retard). Results with special reference to the glucose metabolism].
Topics: Birth Weight; Delayed-Action Preparations; Female; Glucose; Humans; Infant, Newborn; Infant, Prematu | 1975 |
Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Epoprostenol; Female; Humans; Indomethacin; Kinetics; Nylidrin; | 1992 |
Maternal plasma corticotrophin-releasing hormone--elevated in preterm labour but unaffected by indomethacin or nylidrin.
Topics: Adult; Corticotropin-Releasing Hormone; Female; Humans; Hydrocortisone; Indomethacin; Nylidrin; Obst | 1991 |
Decreased numbers of lymphocyte beta 2-adrenoceptors in pregnant women receiving beta 2-adrenergic agonist therapy.
Topics: Adrenergic beta-Agonists; Adult; Cyclic AMP; Female; Humans; Lymphocytes; Nylidrin; Obstetric Labor, | 1990 |
[Pulmonary edema under tocolytic therapy].
Topics: Adult; Ethanolamines; Female; Fenoterol; Humans; Nylidrin; Obstetric Labor, Premature; Pregnancy; Pu | 1985 |
[The motility-inhibiting effect of adrenergic beta receptor stimulating agents in dependence on the duration of pregnancy].
Topics: Adrenergic beta-Agonists; Animals; Epinephrine; Female; Gestational Age; Isoproterenol; Labor, Obste | 1972 |
[Beta adrenergic agents as labor inhibitors].
Topics: Administration, Oral; Adrenergic beta-Agonists; Calcium; Diazepam; Ethanol; Female; Half-Life; Human | 1973 |
[Inhibition of premature labour--anti-inflammatory agents in the prevention of premature birth (author's transl)].
Topics: Administration, Oral; Anti-Inflammatory Agents; Aspirin; Blood Pressure; Blood Vessels; Drug Therapy | 1974 |
[Indications and results of uterine tocolysis].
Topics: Adult; Amino Alcohols; Birth Weight; Female; Humans; Long-Term Care; Muscle Contraction; Nylidrin; O | 1974 |
[Spontaneous motility of the human fallopian tube and pharmacologic effect on it in a in-vitro study].
Topics: Adult; Diazepam; Ethanol; Fallopian Tubes; Female; Humans; In Vitro Techniques; Manometry; Middle Ag | 1974 |
[Long-term pain inhibition with the use of Dilatol].
Topics: Administration, Oral; Adult; Birth Weight; Drug Evaluation; Female; Humans; Injections, Intramuscula | 1974 |
[Effect of beta-sympathicomimetics during labour on the adaption on the newborn infant].
Topics: Acidosis; Adaptation, Physiological; Apgar Score; Asphyxia Neonatorum; Cesarean Section; Female; Ges | 1972 |
[Pharmacological modification of human myometrium activity in the in vitro test. I. Effect of Dilatol on isolated uterine muscle-strip specimens].
Topics: Adult; Female; Humans; Labor, Obstetric; Middle Aged; Muscle Contraction; Nylidrin; Pregnancy; Uteru | 1973 |
[Placental function in dilatol therapy].
Topics: Blood Pressure; Estrogens; Female; Heart Rate; Humans; Nylidrin; Placenta Diseases; Pre-Eclampsia; P | 1973 |
[Bloodsugar levels during treatment with contraction-reducing drugs buphenin (Dilatol) and Th 1165a].
Topics: Blood Glucose; Circadian Rhythm; Female; Glucose Tolerance Test; Humans; Metaproterenol; Nylidrin; P | 1973 |
[Comparative studies on 2 labor inhibitors (TV 399 and buphenin)].
Topics: Acid-Base Equilibrium; Adolescent; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Labor | 1972 |