nylidrin has been researched along with Labor, Premature in 26 studies
Nylidrin: A beta-adrenergic agonist. Nylidrin causes peripheral vasodilation, a positive inotropic effect, and increased gastric volume of gastric juice. It is used in the treatment of peripheral vascular disorders and premature labor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty pregnant women threatened with preterm labor between 24 and 34 weeks of gestation were enrolled in the study." | 6.67 | Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor. ( Eronen, M; Hallman, M; Kurki, T; Pesonen, E; Teramo, K; Ylikorkala, O, 1994) |
| " Taking a minimum birth weight of 2500 g as the criteria of successful treatment, the success rate in the placebo group was 71%, in the Nylidrin hydrochloride group 86%, the Isoxuprine hydrochloride group 75% and the alcohol group 70%." | 5.04 | Treatment of imminent premature labour. ( Castrén, O; Gummerus, M; Saarikoski, S, 1975) |
| "Eighty pregnant women threatened with preterm labor between 24 and 34 weeks of gestation were enrolled in the study." | 2.67 | Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor. ( Eronen, M; Hallman, M; Kurki, T; Pesonen, E; Teramo, K; Ylikorkala, O, 1994) |
| "Nylidrin treatment was accompanied by a 35% rise in COMT activity 3 h later, whereas indomethacin caused no significant change." | 2.67 | Catechol-O-methyltransferase activity in red blood cells in threatened preterm labor; effect of indomethacin and nylidrin. ( Kurki, T; Lindén, IB; Schultz, E; Ylikorkala, O, 1991) |
| "Indomethacin treatment was accompanied by maternal side effects 20% of the time, significantly less commonly (P less than ." | 2.67 | A randomized double-dummy comparison between indomethacin and nylidrin in threatened preterm labor. ( Eronen, M; Kurki, T; Lumme, R; Ylikorkala, O, 1991) |
| "Thirty-three women in preterm labor between 25 and 34 weeks of gestation were studied before, during, and after treatment with indomethacin (n = 16) or nylidrin (n = 17)." | 1.28 | Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin. ( Kurki, T; Viinikka, L; Ylikorkala, O, 1992) |
| "A case of pulmonary edema during tocolytic therapy with beta-mimetic drugs is demonstrated." | 1.27 | [Pulmonary edema under tocolytic therapy]. ( Schöpfel, W; Schreiber, E, 1985) |
| "For prevention of premature labor the betasympathicomimetic drugs buphenin, fenoterol, and ritodrine were administered to 135 patients intravenously for 1 week and afterward orally up to the end of week 37 of gestation." | 1.26 | Evaluation of success in treatment of threatening premature labor by betamimetic drugs. ( Richter, R, 1977) |
| "A twin pregnancy is reported in which a prolonged interval between delivery of twins was accomplished by the use of labor-inhibiting drugs and the placement of a cerevical cerclage." | 1.26 | Delayed interval delivery of a twin pregnancy. ( Thomsen, RJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (73.08) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolff, F | 1 |
| Bolte, A | 1 |
| Berg, R | 1 |
| Eronen, M | 3 |
| Pesonen, E | 2 |
| Kurki, T | 6 |
| Teramo, K | 1 |
| Ylikorkala, O | 6 |
| Hallman, M | 2 |
| Neubüser, D | 2 |
| Richter, R | 3 |
| Bollmann, R | 1 |
| Halle, H | 2 |
| Tschoep, M | 1 |
| Hofer, U | 2 |
| Ammann, K | 1 |
| Thomsen, RJ | 1 |
| Bayer, H | 1 |
| Issel, EP | 1 |
| Hengst, P | 1 |
| Prenzlau, P | 1 |
| Castrén, O | 2 |
| Gummerus, M | 2 |
| Saarikoski, S | 2 |
| Hammacher, K | 1 |
| Hinselmann, M | 1 |
| Viinikka, L | 1 |
| Laatikainen, T | 1 |
| Salminen-Lappalainen, K | 1 |
| Schultz, E | 1 |
| Lindén, IB | 1 |
| Lumme, R | 1 |
| Santala, M | 1 |
| Schreiber, E | 1 |
| Schöpfel, W | 1 |
| Hüter, J | 1 |
| Lammers, G | 1 |
| Mosler, KH | 1 |
| Dornhöfer, W | 1 |
| Linka, F | 1 |
| Koepcke, E | 2 |
| Seidenschnur, G | 2 |
| Jürgens, H | 1 |
| Köppe, I | 1 |
| Räber, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Placebo Controlled Trial of Indomethacin for Tocolysis[NCT01869361] | Early Phase 1 | 0 participants (Actual) | Interventional | 2020-08-01 | Withdrawn (stopped due to Due to much lower than expected numbers of eligible patients and lack of PI time, the study was not started.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nylidrin and Labor, Premature
| Article | Year |
|---|---|
[Clinical use of labor inhibiting substances].
Topics: Amino Alcohols; Female; Germany, East; Humans; Infant Mortality; Nylidrin; Obstetric Labor, Prematur | 1973 |
5 trials available for nylidrin and Labor, Premature
| Article | Year |
|---|---|
Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor.
Topics: Adult; Bronchopulmonary Dysplasia; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; | 1994 |
Treatment of imminent premature labour.
Topics: Birth Weight; Clinical Trials as Topic; Ethanol; Female; Follow-Up Studies; Gestational Age; Humans; | 1975 |
Catechol-O-methyltransferase activity in red blood cells in threatened preterm labor; effect of indomethacin and nylidrin.
Topics: Adult; Catechol O-Methyltransferase; Double-Blind Method; Erythrocytes; Female; Humans; Indomethacin | 1991 |
A randomized double-dummy comparison between indomethacin and nylidrin in threatened preterm labor.
Topics: Adult; Double-Blind Method; Female; Humans; Indomethacin; Nylidrin; Obstetric Labor, Premature; Preg | 1991 |
The effects of indomethacin and a beta-sympathomimetic agent on the fetal ductus arteriosus during treatment of premature labor: a randomized double-blind study.
Topics: Blood Flow Velocity; Cardiac Output, Low; Delivery, Obstetric; Double-Blind Method; Ductus Arteriosu | 1991 |
20 other studies available for nylidrin and Labor, Premature
| Article | Year |
|---|---|
[Does an additional administration of acetylsalicylic acid reduce the requirement of betamimetics in tocolytic treatment? (author's transl)].
Topics: Adrenergic beta-Agonists; Aspirin; Cervix Uteri; Drug Therapy, Combination; Ethanolamines; Female; F | 1981 |
[The influence of partusisten and dilatol on the amino-acid metabolism (author's transl)].
Topics: Administration, Oral; Adrenergic beta-Agonists; Amino Acids; Ethanolamines; Female; Fenoterol; Glyco | 1976 |
Evaluation of success in treatment of threatening premature labor by betamimetic drugs.
Topics: Adrenergic beta-Agonists; Female; Fenoterol; Gestational Age; Humans; Infant, Newborn; Nylidrin; Obs | 1977 |
[Effects of beta-sympathicomimetics on ionogram, transaminases, and ECG in pregnancy (author's transl)].
Topics: Abortion, Therapeutic; Abortion, Threatened; Adrenergic beta-Agonists; Drug Evaluation; Electrocardi | 1979 |
[The oral tocolytic long time therapy and its effects on the child (author's transl)].
Topics: Female; Glucose; Humans; Infant, Newborn; Long-Term Care; Maternal-Fetal Exchange; Nylidrin; Obstetr | 1978 |
[Effectiveness of prolonged uterine relaxation by betamimetic drugs for threatened premature labour (author's transl)].
Topics: Ethanolamines; Female; Fenoterol; Gestational Age; Humans; Infant Mortality; Long-Term Care; Nylidri | 1978 |
Delayed interval delivery of a twin pregnancy.
Topics: Adult; Cervix Uteri; Delivery, Obstetric; Female; Fenoterol; Gestational Age; Humans; Infant, Newbor | 1978 |
[Clinical problems of premature labor. 2. Therapy of threatening and actual premature labor].
Topics: Diazepam; Female; Humans; Nylidrin; Obstetric Labor, Premature; Phenobarbital; Pregnancy; Ritodrine; | 1976 |
[Prevention of premature birth with nylidrin and verapamil (author's transl)].
Topics: Birth Weight; Female; Humans; Infant, Newborn; Injections, Intravenous; Nylidrin; Obstetric Labor, P | 1975 |
[Proceedings: Prophylaxis of threatened premature labor. Clinical results in a prospective comparative study with ritodrine and buphenine].
Topics: Female; Humans; Nylidrin; Obstetric Labor, Premature; Pregnancy; Propanolamines; Ritodrine | 1975 |
[Long term use of buphenin-hchl (Dilydrin retard). Results with special reference to the glucose metabolism].
Topics: Birth Weight; Delayed-Action Preparations; Female; Glucose; Humans; Infant, Newborn; Infant, Prematu | 1975 |
Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Epoprostenol; Female; Humans; Indomethacin; Kinetics; Nylidrin; | 1992 |
Maternal plasma corticotrophin-releasing hormone--elevated in preterm labour but unaffected by indomethacin or nylidrin.
Topics: Adult; Corticotropin-Releasing Hormone; Female; Humans; Hydrocortisone; Indomethacin; Nylidrin; Obst | 1991 |
Decreased numbers of lymphocyte beta 2-adrenoceptors in pregnant women receiving beta 2-adrenergic agonist therapy.
Topics: Adrenergic beta-Agonists; Adult; Cyclic AMP; Female; Humans; Lymphocytes; Nylidrin; Obstetric Labor, | 1990 |
[Pulmonary edema under tocolytic therapy].
Topics: Adult; Ethanolamines; Female; Fenoterol; Humans; Nylidrin; Obstetric Labor, Premature; Pregnancy; Pu | 1985 |
[Beta adrenergic agents as labor inhibitors].
Topics: Administration, Oral; Adrenergic beta-Agonists; Calcium; Diazepam; Ethanol; Female; Half-Life; Human | 1973 |
[Inhibition of premature labour--anti-inflammatory agents in the prevention of premature birth (author's transl)].
Topics: Administration, Oral; Anti-Inflammatory Agents; Aspirin; Blood Pressure; Blood Vessels; Drug Therapy | 1974 |
[Indications and results of uterine tocolysis].
Topics: Adult; Amino Alcohols; Birth Weight; Female; Humans; Long-Term Care; Muscle Contraction; Nylidrin; O | 1974 |
[Long-term pain inhibition with the use of Dilatol].
Topics: Administration, Oral; Adult; Birth Weight; Drug Evaluation; Female; Humans; Injections, Intramuscula | 1974 |
[Comparative studies on 2 labor inhibitors (TV 399 and buphenin)].
Topics: Acid-Base Equilibrium; Adolescent; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Labor | 1972 |