nu-7026 and Carcinoma--Hepatocellular

nu-7026 has been researched along with Carcinoma--Hepatocellular* in 1 studies

Other Studies

1 other study(ies) available for nu-7026 and Carcinoma--Hepatocellular

Article	Year
The effect of inhibitors of phosphatidylinositol 3-kinase-related kinases on dibenzo[def,p]chrysene genotoxicity measured by γH2AX levels and neutral comet assay in HepG2 human hepatocellular cancer cells. Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 63 In the study the modulating effect of inhibition of phosphatidylinositol 3-kinase-related kinases (PIKK): ATM (Ataxia Telangiectasia Mutated), ATR (Ataxia Telangiectasia and Rad3 Related) and DNA-PK (DNA-dependent protein kinase) on genotoxicity of dibenzo[def,p]chrysene (DBC) in HepG2 human hepatocellular cancer cells was investigated. The cytotoxicity of DBC was determined, also in combination with PIKK inhibitors, using the MTT reduction assay. The high cytotoxicity of DBC was observed after 72 h incubation (IC Topics: Benzopyrenes; Carcinoma, Hepatocellular; Cell Survival; Chromones; Comet Assay; DNA Damage; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Morpholines; Phosphatidylinositol 3-Kinase; Protein Kinase Inhibitors	2020

Article

Year

The effect of inhibitors of phosphatidylinositol 3-kinase-related kinases on dibenzo[def,p]chrysene genotoxicity measured by γH2AX levels and neutral comet assay in HepG2 human hepatocellular cancer cells.

Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 63

In the study the modulating effect of inhibition of phosphatidylinositol 3-kinase-related kinases (PIKK): ATM (Ataxia Telangiectasia Mutated), ATR (Ataxia Telangiectasia and Rad3 Related) and DNA-PK (DNA-dependent protein kinase) on genotoxicity of dibenzo[def,p]chrysene (DBC) in HepG2 human hepatocellular cancer cells was investigated. The cytotoxicity of DBC was determined, also in combination with PIKK inhibitors, using the MTT reduction assay. The high cytotoxicity of DBC was observed after 72 h incubation (IC

Topics: Benzopyrenes; Carcinoma, Hepatocellular; Cell Survival; Chromones; Comet Assay; DNA Damage; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Morpholines; Phosphatidylinositol 3-Kinase; Protein Kinase Inhibitors

2020