nsc 664704 has been researched along with Allergic Encephalomyelitis in 1 studies
kenpaullone: inhibits CDK1/cyclin B; structure in first source
kenpaullone : An indolobenzazepine that is paullone in which the hydrogen at position 9 is replaced by a bromo substituent. It is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3beta (GSK3beta).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kenpaullone and Roscovitine suppressed experimental autoimmune encephalomyelitis (EAE), a typical Th17-mediated autoimmune disease model." | 1.39 | CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice. ( Asakawa, M; Ito, M; Kimura, A; Kondo, T; Kotani, H; Nagai, S; Tani, I; Tsuruta, S; Wei, X; Yoshida, H; Yoshimura, A, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshida, H | 1 |
| Kotani, H | 1 |
| Kondo, T | 1 |
| Tani, I | 1 |
| Wei, X | 1 |
| Tsuruta, S | 1 |
| Kimura, A | 1 |
| Asakawa, M | 1 |
| Ito, M | 1 |
| Nagai, S | 1 |
| Yoshimura, A | 1 |
1 other study available for nsc 664704 and Allergic Encephalomyelitis
| Article | Year |
|---|---|
CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice.
Topics: Animals; Benzazepines; Cell Differentiation; Cyclin-Dependent Kinases; Encephalomyelitis, Autoimmune | 2013 |