nsc-4347 and Schistosomiasis

nsc-4347 has been researched along with Schistosomiasis* in 1 studies

Other Studies

1 other study(ies) available for nsc-4347 and Schistosomiasis

Article	Year
A benzoic acid derivative and flavokawains from Piper species as schistosomiasis vector controls. Molecules (Basel, Switzerland), 2014, Apr-23, Volume: 19, Issue:4 The search of alternative compounds to control tropical diseases such as schistosomiasis has pointed to secondary metabolites derived from natural sources. Piper species are candidates in strategies to control the transmission of schistosomiasis due to their production of molluscicidal compounds. A new benzoic acid derivative and three flavokawains from Piper diospyrifolium, P. cumanense and P. gaudichaudianum displayed significant activities against Biomphalaria glabrata snails. Additionally, "in silico" studies were performed using docking assays and Molecular Interaction Fields to evaluate the physical-chemical differences among the compounds in order to characterize the observed activities of the test compounds against Biomphalaria glabrata snails. Topics: Animals; Antiparasitic Agents; Benzoic Acid; Biological Products; Chalcones; Disease Reservoirs; Humans; Inhibitory Concentration 50; Life Cycle Stages; Molecular Docking Simulation; Piper; Plant Extracts; Plant Leaves; Schistosoma mansoni; Schistosomiasis; Snails; Structure-Activity Relationship	2014

Article

Year

A benzoic acid derivative and flavokawains from Piper species as schistosomiasis vector controls.

Molecules (Basel, Switzerland), 2014, Apr-23, Volume: 19, Issue:4

The search of alternative compounds to control tropical diseases such as schistosomiasis has pointed to secondary metabolites derived from natural sources. Piper species are candidates in strategies to control the transmission of schistosomiasis due to their production of molluscicidal compounds. A new benzoic acid derivative and three flavokawains from Piper diospyrifolium, P. cumanense and P. gaudichaudianum displayed significant activities against Biomphalaria glabrata snails. Additionally, "in silico" studies were performed using docking assays and Molecular Interaction Fields to evaluate the physical-chemical differences among the compounds in order to characterize the observed activities of the test compounds against Biomphalaria glabrata snails.

Topics: Animals; Antiparasitic Agents; Benzoic Acid; Biological Products; Chalcones; Disease Reservoirs; Humans; Inhibitory Concentration 50; Life Cycle Stages; Molecular Docking Simulation; Piper; Plant Extracts; Plant Leaves; Schistosoma mansoni; Schistosomiasis; Snails; Structure-Activity Relationship

2014