nsc-4347 has been researched along with Ovarian-Neoplasms* in 1 studies
1 other study(ies) available for nsc-4347 and Ovarian-Neoplasms
| Article | Year |
|---|---|
Anti-inflammatory activity and cytotoxicity against ovarian cancer cell lines by amide alkaloids and piperic esters isolated from Piper longum fruits: In vitro assessments and molecular docking simulation.
Three new amide alkaloids, piperlongumamides D-F (14, 19, and 32); a new piperic ester, piperlongumester A (45); and two new natural compounds, methyl (2E,4Z)-5-(1,3-benzodioxol-5-yl)penta-2,4-dienoate (46) and trans-piperolein B ester (47), along with 41 known compounds were isolated from the fruits of Piper longum L. Their structures were identified by analyzing spectroscopic data, including mass spectrometry, 1D, and 2D NMR data. The anti-inflammatory and cytotoxic activities of all isolated compounds (1-47) were evaluated. Compounds 3, 6, and 19 inhibited nitric oxide production with IC Topics: Alkaloids; Amides; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Esters; Female; Fruit; Humans; Molecular Docking Simulation; Molecular Structure; Ovarian Neoplasms; Piper | 2022 |