ns 1619 has been researched along with Stroke in 1 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Romine, JL | 1 |
| Martin, SW | 1 |
| Meanwell, NA | 1 |
| Gribkoff, VK | 1 |
| Boissard, CG | 1 |
| Dworetzky, SI | 1 |
| Natale, J | 1 |
| Moon, S | 1 |
| Ortiz, A | 1 |
| Yeleswaram, S | 1 |
| Pajor, L | 1 |
| Gao, Q | 1 |
| Starrett, JE | 1 |
1 other study available for ns 1619 and Stroke
| Article | Year |
|---|---|
3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: opener of large-conductance Ca(2+)-activated potassium (maxi-K) channels, identification, solubility, and SAR.
Topics: Animals; Brain; Crystallography, X-Ray; Female; In Vitro Techniques; Ion Channel Gating; Large-Condu | 2007 |