ns 1619 has been researched along with Prostatic Hyperplasia in 1 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Partial bladder outlet obstruction (PBOO) was surgically induced in male New Zealand White rabbits." | 1.36 | Detrusor overactivity is associated with downregulation of large-conductance calcium- and voltage-activated potassium channel protein. ( Alanzi, J; Chacko, S; Chang, S; Gomes, CM; Hypolite, JA; Malkowicz, B; Marx, J; Wein, AJ; Zderic, SA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, S | 1 |
| Gomes, CM | 1 |
| Hypolite, JA | 1 |
| Marx, J | 1 |
| Alanzi, J | 1 |
| Zderic, SA | 1 |
| Malkowicz, B | 1 |
| Wein, AJ | 1 |
| Chacko, S | 1 |
1 other study available for ns 1619 and Prostatic Hyperplasia
| Article | Year |
|---|---|
Detrusor overactivity is associated with downregulation of large-conductance calcium- and voltage-activated potassium channel protein.
Topics: Aged; Aged, 80 and over; Animals; Benzimidazoles; Case-Control Studies; Cells, Cultured; Disease Mod | 2010 |