ns 1619 has been researched along with Pregnancy in 8 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levcromakalim was equally effective in inhibiting contractions of rings from all 3 groups." | 1.31 | Role of nucleotide cyclases in the inhibition of pregnant rat uterine contractions by the openers of potassium channels. ( Chwalisz, K; Garfield, RE; Longo, M; Okawa, T; Saade, GR; Vedernikov, YP, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, R | 1 |
| Hu, XQ | 1 |
| Xiao, D | 1 |
| Yang, S | 1 |
| Wilson, SM | 1 |
| Longo, LD | 1 |
| Zhang, L | 1 |
| Sadlonova, V | 1 |
| Franova, S | 1 |
| Dokus, K | 1 |
| Janicek, F | 1 |
| Visnovsky, J | 1 |
| Sadlonova, J | 1 |
| Provencher, M | 1 |
| Houde, V | 1 |
| Brochu, M | 2 |
| St-Louis, J | 2 |
| Gáspár, T | 1 |
| Katakam, P | 1 |
| Snipes, JA | 1 |
| Kis, B | 1 |
| Domoki, F | 1 |
| Bari, F | 1 |
| Busija, DW | 1 |
| Khan, RN | 1 |
| Smith, SK | 1 |
| Ashford, ML | 1 |
| Okawa, T | 2 |
| Vedernikov, YP | 2 |
| Saade, GR | 2 |
| Longo, M | 2 |
| Olson, GL | 1 |
| Chwalisz, K | 2 |
| Garfield, RE | 2 |
| Cadorette, C | 1 |
| Sicotte, B | 1 |
8 other studies available for ns 1619 and Pregnancy
| Article | Year |
|---|---|
Chronic hypoxia inhibits pregnancy-induced upregulation of SKCa channel expression and function in uterine arteries.
Topics: Animals; Benzimidazoles; Chronic Disease; Female; Hypoxia; Indoles; Oximes; Pregnancy; Sheep; Small- | 2013 |
Participation of BKCa2+ and KATP potassium ion channels in the contractility of human term pregnant myometrium in in vitro conditions.
Topics: Benzimidazoles; Female; Humans; In Vitro Techniques; KATP Channels; Large-Conductance Calcium-Activa | 2011 |
Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats.
Topics: Aldosterone; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Canrenoic Acid; Cro | 2012 |
Delayed neuronal preconditioning by NS1619 is independent of calcium activated potassium channels.
Topics: Animals; Benzimidazoles; Cell Survival; Cells, Cultured; Female; Ischemic Preconditioning; Male; Neu | 2008 |
Contribution of calcium-sensitive potassium channels to NS1619-induced relaxation in human pregnant myometrium.
Topics: Benzimidazoles; Calcium; Drug Evaluation, Preclinical; Female; Humans; In Vitro Techniques; Muscle R | 1998 |
Roles of potassium channels and nitric oxide in modulation of uterine contractions in rat pregnancy.
Topics: Adenosine Triphosphate; Animals; Benzimidazoles; Cromakalim; Female; Gestational Age; Glyburide; In | 1999 |
Effects of potassium channel modulators on myotropic responses of aortic rings of pregnant rats.
Topics: Animals; Aorta; Benzimidazoles; Cromakalim; Female; Glyburide; In Vitro Techniques; Muscle, Smooth, | 2000 |
Role of nucleotide cyclases in the inhibition of pregnant rat uterine contractions by the openers of potassium channels.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aminoquinolines; Animals; Benzimidazoles; C | 2000 |