ns 1619 has been researched along with Myocardial Ischemia in 2 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, W | 1 |
| Liu, Y | 1 |
| Wang, S | 1 |
| McDonald, T | 1 |
| Van Eyk, JE | 1 |
| Sidor, A | 1 |
| O'Rourke, B | 1 |
| Wang, X | 1 |
| Yin, C | 1 |
| Xi, L | 1 |
| Kukreja, RC | 1 |
2 other studies available for ns 1619 and Myocardial Ischemia
| Article | Year |
|---|---|
Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membrane.
Topics: Adenosine Triphosphate; Animals; Benzimidazoles; Calcium; Charybdotoxin; Cytoprotection; Guinea Pigs | 2002 |
Opening of Ca2+-activated K+ channels triggers early and delayed preconditioning against I/R injury independent of NOS in mice.
Topics: Animals; Animals, Outbred Strains; Benzimidazoles; Cardiotonic Agents; Ischemic Preconditioning, Myo | 2004 |