ns 1619 has been researched along with Muscle Relaxation in 9 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takagi, H | 1 |
| Hashitani, H | 1 |
| Malysz, J | 1 |
| Buckner, SA | 1 |
| Daza, AV | 1 |
| Milicic, I | 1 |
| Perez-Medrano, A | 1 |
| Gopalakrishnan, M | 1 |
| Biagi, G | 1 |
| Calderone, V | 1 |
| Giorgi, I | 1 |
| Livi, O | 1 |
| Martinotti, E | 1 |
| Martelli, A | 1 |
| Nardi, A | 1 |
| Macmillan, S | 1 |
| Sheridan, RD | 1 |
| Chilvers, ER | 1 |
| Patmore, L | 1 |
| Holland, M | 1 |
| Langton, PD | 1 |
| Standen, NB | 1 |
| Boyle, JP | 1 |
| Corompt, E | 1 |
| Bessard, G | 1 |
| Lantuejoul, S | 1 |
| Naline, E | 1 |
| Advenier, C | 1 |
| Devillier, P | 1 |
| Khan, RN | 1 |
| Smith, SK | 1 |
| Ashford, ML | 1 |
| White, R | 1 |
| Hiley, CR | 1 |
| Chen, SJ | 1 |
| Wu, CC | 1 |
| Yang, SN | 1 |
| Lin, CI | 1 |
| Yen, MH | 1 |
9 other studies available for ns 1619 and Muscle Relaxation
| Article | Year |
|---|---|
Effects of K(+) channel openers on spontaneous action potentials in detrusor smooth muscle of the guinea-pig urinary bladder.
Topics: Action Potentials; Animals; Benzimidazoles; Cyclic AMP; Guinea Pigs; Ion Channel Gating; KCNQ Potass | 2016 |
Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle.
Topics: Animals; Benzimidazoles; Electric Stimulation; Guinea Pigs; Indoles; Muscle Relaxation; Muscle, Smoo | 2004 |
1,5-Diarylsubstituted 1,2,3-triazoles as potassium channel activators. VI.
Topics: Animals; Benzimidazoles; Inhibitory Concentration 50; Models, Chemical; Muscle Relaxation; Muscle, S | 2004 |
A comparison of the effects of SCA40, NS 004 and NS 1619 on large conductance Ca(2+)-activated K+ channels in bovine tracheal smooth muscle cells in culture.
Topics: Animals; Benzimidazoles; Calcium; Cattle; Cells, Cultured; Chlorophenols; Electric Conductivity; Imi | 1995 |
Effects of the BKCa channel activator, NS1619, on rat cerebral artery smooth muscle.
Topics: Animals; Apamin; Benzimidazoles; Calcium; Cerebral Arteries; Glyburide; Male; Membrane Potentials; M | 1996 |
Inhibitory effects of large Ca2+-activated K+ channel blockers on beta-adrenergic- and NO-donor-mediated relaxations of human and guinea-pig airway smooth muscles.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Albuterol; Animals; Benzimidazoles; Bronch | 1998 |
Contribution of calcium-sensitive potassium channels to NS1619-induced relaxation in human pregnant myometrium.
Topics: Benzimidazoles; Calcium; Drug Evaluation, Preclinical; Female; Humans; In Vitro Techniques; Muscle R | 1998 |
The actions of the cannabinoid receptor antagonist, SR 141716A, in the rat isolated mesenteric artery.
Topics: Animals; Benzimidazoles; Calcium; Cannabinoids; Carbachol; Cromakalim; Dose-Response Relationship, D | 1998 |
Abnormal activation of K(+) channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence.
Topics: Animals; Aorta; Apamin; Benzimidazoles; Charybdotoxin; Drug Interactions; Enzyme Inhibitors; Glyburi | 2000 |