ns 1619 has been researched along with Migraine Disorders in 1 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Migraine is a common, disabling, neurological problem whose acute management would benefit from the development of purely neurally acting therapies." | 1.35 | Large conductance calcium-activated potassium channels (BKCa) modulate trigeminovascular nociceptive transmission. ( Goadsby, PJ; Immke, DC; Storer, RJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Storer, RJ | 1 |
| Immke, DC | 1 |
| Goadsby, PJ | 1 |
1 other study available for ns 1619 and Migraine Disorders
| Article | Year |
|---|---|
Large conductance calcium-activated potassium channels (BKCa) modulate trigeminovascular nociceptive transmission.
Topics: Action Potentials; Animals; Benzimidazoles; Cats; Cerebral Arteries; Electric Stimulation; Evoked Po | 2009 |