ns 1619 has been researched along with Injury, Myocardial Reperfusion in 8 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heinen, A | 1 |
| Ströthoff, M | 1 |
| Schmidt, A | 1 |
| Stracke, N | 1 |
| Behmenburg, F | 1 |
| Bauer, I | 1 |
| Hollmann, MW | 1 |
| Huhn, R | 1 |
| Wrzosek, A | 1 |
| Lu, T | 1 |
| Jiang, B | 1 |
| Wang, XL | 1 |
| Lee, HC | 1 |
| Borchert, GH | 1 |
| Yang, C | 1 |
| Kolár, F | 1 |
| Cao, Y | 1 |
| Zhang, SZ | 1 |
| Zhao, SQ | 1 |
| Bruce, IC | 1 |
| Wang, X | 1 |
| Yin, C | 1 |
| Xi, L | 1 |
| Kukreja, RC | 1 |
| Cao, CM | 1 |
| Xia, Q | 1 |
| Gao, Q | 1 |
| Chen, M | 1 |
| Wong, TM | 1 |
| Shi, Y | 1 |
| Jiang, MT | 1 |
| Su, J | 1 |
| Hutchins, W | 1 |
| Konorev, E | 1 |
| Baker, JE | 1 |
8 other studies available for ns 1619 and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Pharmacological options to protect the aged heart from ischemia and reperfusion injury by targeting the PKA-BK(Ca) signaling pathway.
Topics: Age Factors; Aging; Animals; Benzimidazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytopr | 2014 |
The potassium channel opener NS1619 modulates calcium homeostasis in muscle cells by inhibiting SERCA.
Topics: Animals; Benzimidazoles; Calcium; Cell Line; Guinea Pigs; Homeostasis; Ischemia; Mice; Muscle Contra | 2014 |
Coronary arterial BK channel dysfunction exacerbates ischemia/reperfusion-induced myocardial injury in diabetic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Caveolae; Cells, C | 2016 |
Mitochondrial BKCa channels contribute to protection of cardiomyocytes isolated from chronically hypoxic rats.
Topics: Animals; Benzimidazoles; Blotting, Western; Cell Separation; Cell Survival; Cells, Cultured; Chronic | 2011 |
The mitochondrial Ca(2+)-activated K(+) channel contributes to cardioprotection by limb remote ischemic preconditioning in rat.
Topics: Animals; Benzimidazoles; Indoles; Ischemic Preconditioning, Myocardial; Male; Membrane Potential, Mi | 2011 |
Opening of Ca2+-activated K+ channels triggers early and delayed preconditioning against I/R injury independent of NOS in mice.
Topics: Animals; Animals, Outbred Strains; Benzimidazoles; Cardiotonic Agents; Ischemic Preconditioning, Myo | 2004 |
Calcium-activated potassium channel triggers cardioprotection of ischemic preconditioning.
Topics: Animals; ATP-Binding Cassette Transporters; Benzimidazoles; Cell Survival; Coronary Circulation; Dec | 2005 |
Mitochondrial big conductance KCa channel and cardioprotection in infant rabbit heart.
Topics: Animals; Animals, Newborn; Benzimidazoles; Coronary Circulation; Heart; Heart Rate; Hypoxia; Indoles | 2007 |