ns 1619 has been researched along with Epileptiform Neuralgia in 1 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trigeminal neuralgia is a paroxysmal disorder with severely disabling facial pain and thus continues to be a real therapeutic challenge." | 1.36 | [BK(Ca) channel agonist NS1619 and Kv channel antagonist 4-AP on the facial mechanical pain threshold in a rat model of chronic constriction injury of the infraorbital nerve]. ( Li, N; Liu, CY; Ma, B; Zhao, YF, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, CY | 1 |
| Li, N | 1 |
| Zhao, YF | 1 |
| Ma, B | 1 |
1 other study available for ns 1619 and Epileptiform Neuralgia
| Article | Year |
|---|---|
[BK(Ca) channel agonist NS1619 and Kv channel antagonist 4-AP on the facial mechanical pain threshold in a rat model of chronic constriction injury of the infraorbital nerve].
Topics: 4-Aminopyridine; Animals; Benzimidazoles; Constriction; Facial Pain; Injections, Intralesional; Kv1. | 2010 |