Page last updated: 2024-11-01

ns 1619 and Diabetes Mellitus, Adult-Onset

ns 1619 has been researched along with Diabetes Mellitus, Adult-Onset in 1 studies

NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).

Research Excerpts

ExcerptRelevanceReference
"We hypothesized that in Type 2 diabetes, the impaired endothelium-dependent relaxation is due to a loss of endothelium-derived hyperpolarization (EDH) that is regulated by impaired ion channel function."1.40Type 2 diabetes: increased expression and contribution of IKCa channels to vasodilation in small mesenteric arteries of ZDF rats. ( Endemann, DH; Resch, M; Riegger, GA; Schach, C; Schmid, PM, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schach, C1
Resch, M1
Schmid, PM1
Riegger, GA1
Endemann, DH1

Other Studies

1 other study available for ns 1619 and Diabetes Mellitus, Adult-Onset

ArticleYear
Type 2 diabetes: increased expression and contribution of IKCa channels to vasodilation in small mesenteric arteries of ZDF rats.
    American journal of physiology. Heart and circulatory physiology, 2014, Oct-15, Volume: 307, Issue:8

    Topics: Acetylcholine; Animals; Apamin; Benzimidazoles; Calcium Channel Agonists; Charybdotoxin; Cyclooxygen

2014