ns 1619 has been researched along with Diabetes Mellitus, Adult-Onset in 1 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We hypothesized that in Type 2 diabetes, the impaired endothelium-dependent relaxation is due to a loss of endothelium-derived hyperpolarization (EDH) that is regulated by impaired ion channel function." | 1.40 | Type 2 diabetes: increased expression and contribution of IKCa channels to vasodilation in small mesenteric arteries of ZDF rats. ( Endemann, DH; Resch, M; Riegger, GA; Schach, C; Schmid, PM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schach, C | 1 |
| Resch, M | 1 |
| Schmid, PM | 1 |
| Riegger, GA | 1 |
| Endemann, DH | 1 |
1 other study available for ns 1619 and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Type 2 diabetes: increased expression and contribution of IKCa channels to vasodilation in small mesenteric arteries of ZDF rats.
Topics: Acetylcholine; Animals; Apamin; Benzimidazoles; Calcium Channel Agonists; Charybdotoxin; Cyclooxygen | 2014 |