Page last updated: 2024-11-01

ns 1619 and Cerebellar Ataxia

ns 1619 has been researched along with Cerebellar Ataxia in 1 studies

NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).

Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alviña, K1
Khodakhah, K1

Other Studies

1 other study available for ns 1619 and Cerebellar Ataxia

ArticleYear
KCa channels as therapeutic targets in episodic ataxia type-2.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, May-26, Volume: 30, Issue:21

    Topics: Analysis of Variance; Animals; Benzimidazoles; Cerebellar Ataxia; Cerebellum; Chlorzoxazone; Disease

2010