ns 1619 has been researched along with Cancer of Ovary in 1 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our data demonstrate that NS1619 inhibits the proliferation of A2780 cells in a dosage and time dependent manner IC50=31." | 1.35 | The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells. ( Han, X; Han, Z; Huang, X; Lu, Y; Ma, D; Ma, X; Wang, G; Wang, H; Wu, P; Xi, L; Zhou, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, X | 1 |
| Xi, L | 1 |
| Wang, H | 1 |
| Huang, X | 1 |
| Ma, X | 2 |
| Han, Z | 1 |
| Wu, P | 1 |
| Lu, Y | 1 |
| Wang, G | 1 |
| Zhou, J | 1 |
| Ma, D | 1 |
1 other study available for ns 1619 and Cancer of Ovary
| Article | Year |
|---|---|
The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; DNA Fra | 2008 |