Page last updated: 2024-11-01

ns 1619 and Bronchial Hyperreactivity

ns 1619 has been researched along with Bronchial Hyperreactivity in 1 studies

NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kocmalova, M1
Oravec, M1
Adamkov, M1
Sadlonova, V1
Kazimierova, I1
Medvedova, I1
Joskova, M1
Franova, S1
Sutovska, M1

Other Studies

1 other study available for ns 1619 and Bronchial Hyperreactivity

ArticleYear
Potassium ion channels and allergic asthma.
    Advances in experimental medicine and biology, 2015, Volume: 838

    Topics: Administration, Inhalation; Airway Resistance; Animals; Benzimidazoles; Bronchial Hyperreactivity; B

2015