ns 1619 has been researched along with Brain Injuries in 6 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armstead, WM | 6 |
| Hecker, JG | 1 |
| Salvucci, A | 1 |
6 other studies available for ns 1619 and Brain Injuries
| Article | Year |
|---|---|
Heat shock protein modulation of KATP and KCa channel cerebrovasodilation after brain injury.
Topics: Animals; Animals, Newborn; Benzimidazoles; Blood Pressure; Brain Injuries; Calcitonin Gene-Related P | 2005 |
Vasopressin impairs K(ATP) and K(ca) channel function after brain injury.
Topics: Animals; Animals, Newborn; Benzimidazoles; Brain Injuries; Cerebral Arteries; Cerebral Veins; Cromak | 2000 |
Vasopressin-induced protein kinase C-dependent superoxide generation contributes to atp-sensitive potassium channel but not calcium-sensitive potassium channel function impairment after brain injury.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Arteries; Benzimidazoles; Brain Injuries; Brain I | 2001 |
Vasopressin induced cyclooxygenase dependent superoxide generation contributes to K(+) channel function impairment after brain injury.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Benzimidaz | 2001 |
Endothelin-Induced cyclooxygenase-dependent superoxide generation contributes to K+ channel functional impairment after brain injury.
Topics: Animals; Animals, Newborn; ATP-Binding Cassette Transporters; Benzimidazoles; Brain Injuries; Calcit | 2001 |
Protein tyrosine kinase and mitogen-activated protein kinase activation contribute to K(ATP) and K(ca) channel impairment after brain injury.
Topics: Animals; Animals, Newborn; Benzimidazoles; Brain; Brain Injuries; Calcitonin Gene-Related Peptide; C | 2002 |