ns 1619 has been researched along with Anoxia, Brain in 3 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
| Excerpt | Relevance | Reference |
|---|---|---|
| "For aprikalim (n=7), values were as follows: 6+/-2% versus 8+/-2% at 10(-5) mol/L, 22+/-6% versus 15+/-3% at 5 x 10(-5) mol/L, and 41+/-5% versus 32+/-6% at 10(-4) mol/L." | 1.30 | Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets. ( Bari, F; Busija, DW; Domoki, F; Veltkamp, R, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Veltkamp, R | 1 |
| Domoki, F | 1 |
| Bari, F | 1 |
| Busija, DW | 1 |
| Ben-Haim, G | 1 |
| Armstead, WM | 1 |
| Rundén-Pran, E | 1 |
| Haug, FM | 1 |
| Storm, JF | 1 |
| Ottersen, OP | 1 |
3 other studies available for ns 1619 and Anoxia, Brain
| Article | Year |
|---|---|
Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzimidazoles; Calcitonin Gene-Related Peptide; Fe | 1998 |
Stimulus duration-dependent contribution of k(ca) channel activation and cAMP to hypoxic cerebrovasodilation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzimidazoles; Blood Gas Analysis; Blood Pressure; | 2000 |
BK channel activity determines the extent of cell degeneration after oxygen and glucose deprivation: a study in organotypical hippocampal slice cultures.
Topics: Animals; Benzimidazoles; Cell Death; Cell Hypoxia; Dose-Response Relationship, Drug; Fluorescent Dye | 2002 |