Page last updated: 2024-11-01

ns 1619 and Alloxan Diabetes

ns 1619 has been researched along with Alloxan Diabetes in 6 studies

NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Corrochano, R1
La Fuente, J1
Cuevas, P1
Fernández, A1
Chen, M1
Sáenz de Tejada, I1
Angulo, J1
Vetri, F2
Qi, M1
Xu, H2
Oberholzer, J1
Paisansathan, C2
Wang, Y1
Zhang, HT1
Su, XL1
Deng, XL1
Yuan, BX1
Zhang, W1
Wang, XF1
Yang, YB1
Vahabi, B1
Lawson, K1
McKay, NG1
Sellers, DJ1
Pelligrino, DA1
Morikawa, K1
Matoba, T1
Kubota, H1
Hatanaka, M1
Fujiki, T1
Takahashi, S1
Takeshita, A1
Shimokawa, H1

Other Studies

6 other studies available for ns 1619 and Alloxan Diabetes

ArticleYear
Ca2+ -activated K+ channel (KCa) stimulation improves relaxant capacity of PDE5 inhibitors in human penile arteries and recovers the reduced efficacy of PDE5 inhibition in diabetic erectile dysfunction.
    British journal of pharmacology, 2013, Volume: 169, Issue:2

    Topics: Adult; Aged; Animals; Benzimidazoles; Carbolines; Cyclic GMP; Diabetes Mellitus, Experimental; Dose-

2013
Impairment of neurovascular coupling in Type 1 Diabetes Mellitus in rats is prevented by pancreatic islet transplantation and reversed by a semi-selective PKC inhibitor.
    Brain research, 2017, 01-15, Volume: 1655

    Topics: Animals; Arterioles; Benzimidazoles; Cardiovascular Agents; Diabetes Mellitus, Experimental; Diabete

2017
Experimental diabetes mellitus down-regulates large-conductance Ca2+-activated K+ channels in cerebral artery smooth muscle and alters functional conductance.
    Current neurovascular research, 2010, Volume: 7, Issue:2

    Topics: Animals; Benzimidazoles; Blood Glucose; Body Weight; Cerebral Arteries; Diabetes Mellitus, Experimen

2010
Phasic activity of urinary bladder smooth muscle in the streptozotocin-induced diabetic rat: effect of potassium channel modulators.
    European journal of pharmacology, 2011, Jun-25, Volume: 660, Issue:2-3

    Topics: Animals; Benzimidazoles; Cromakalim; Diabetes Mellitus, Experimental; In Vitro Techniques; Ion Chann

2011
Impairment of neurovascular coupling in type 1 diabetes mellitus in rats is linked to PKC modulation of BK(Ca) and Kir channels.
    American journal of physiology. Heart and circulatory physiology, 2012, Mar-15, Volume: 302, Issue:6

    Topics: Animals; Arterioles; Benzimidazoles; Cerebrovascular Circulation; Diabetes Complications; Diabetes M

2012
Influence of diabetes mellitus, hypercholesterolemia, and their combination on EDHF-mediated responses in mice.
    Journal of cardiovascular pharmacology, 2005, Volume: 45, Issue:5

    Topics: Acetylcholine; Animals; Apolipoproteins E; Benzimidazoles; Biological Factors; Blood Glucose; Diabet

2005