novobiocin has been researched along with Respiratory-Tract-Infections* in 13 studies
1 review(s) available for novobiocin and Respiratory-Tract-Infections
Article | Year |
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[The use of antibiotics in otologic practice].
Topics: Acute Disease; Anti-Bacterial Agents; Bacitracin; Bronchitis; Chloramphenicol; Chronic Disease; Ear Diseases; Humans; Labyrinth Diseases; Laryngitis; Neomycin; Novobiocin; Otitis Externa; Otitis Media; Penicillins; Pneumococcal Infections; Polymyxins; Respiratory Tract Infections; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Tetracycline; Tonsillitis; Tracheal Diseases | 1969 |
12 other study(ies) available for novobiocin and Respiratory-Tract-Infections
Article | Year |
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Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents.
Our strategy to combat resistant bacteria consisted of targeting the GyrB/ParE ATP-binding sites located on bacterial DNA gyrase and topoisomerase IV and not utilized by marketed antibiotics. Screening around the minimal ethyl urea binding motif led to the identification of isoquinoline ethyl urea 13 as a promising starting point for fragment evolution. The optimization was guided by structure-based design and focused on antibacterial activity in vitro and in vivo, culminating in the discovery of unprecedented substituents able to interact with conserved residues within the ATP-binding site. A detailed characterization of the lead compound highlighted the potential for treatment of the problematic fluoroquinolone-resistant MRSA, VRE, and S. pneumoniae, and the possibility to offer patients an intravenous-to-oral switch therapy was supported by the identification of a suitable prodrug concept. Eventually, hERG K-channel block was identified as the main limitation of this chemical series, and efforts toward its minimization are reported. Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Drug Discovery; Gram-Negative Bacteria; Half-Life; Hydrogen Bonding; Isoquinolines; Microbial Sensitivity Tests; Potassium Channels; Rats; Respiratory Tract Infections; Solubility; Urea | 2017 |
Efficacy of tetracycline/novobiocin combination against canine upper respiratory infections.
Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Drug Therapy, Combination; Novobiocin; Respiratory Tract Infections; Tetracyclines | 1980 |
Serological types of Diplococcus pneumoniae strains isolated in Germany. Comparison with type patterns in other countries.
Topics: Cephaloridine; Chloramphenicol; Drug Combinations; Erythromycin; Fusidic Acid; Germany, West; Humans; Lincomycin; Microbial Sensitivity Tests; Nitrofurans; Novobiocin; Penicillin Resistance; Penicillins; Respiratory Tract Infections; Serotyping; Sputum; Streptococcus pneumoniae; Sulfamethoxazole; Sulfonamides; Tetracycline; Trimethoprim; Vancomycin | 1974 |
[Application of aminodeoxykanamycin (Kanendomycin 'Meiji') in the field of internal medicine].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephaloridine; Chloramphenicol; Colistin; Erythromycin; Escherichia coli; Female; Gentamicins; Humans; Kanamycin; Lincomycin; Male; Meningitis; Microbial Sensitivity Tests; Middle Aged; Novobiocin; Penicillins; Radiography; Respiratory Tract Infections; Sepsis; Staphylococcus; Streptococcus; Streptomycin; Sulfonamides; Tetracycline; Urinary Tract Infections | 1971 |
[CLINICAL AND PHARMACOLOGICAL STUDY OF A COMBINATION OF NOVOBIOCIN AND TETRACYCLINE IN PEDIATRICS].
Topics: Child; Dermatology; Focal Infection; Focal Infection, Dental; Humans; Infant; Novobiocin; Otitis; Pediatrics; Pharyngitis; Respiratory Tract Infections; Sinusitis; Tetracycline | 1963 |
[KITASAMYCIN. EXPERIMENTAL "IN VITRO" STUDY AND 1ST CLINICAL RESULTS].
Topics: Anti-Bacterial Agents; Chlortetracycline; Dermatology; Drug Resistance; Drug Resistance, Microbial; Erythromycin; Gastroenterology; In Vitro Techniques; Kitasamycin; Leukemia; Methicillin; Novobiocin; Osteomyelitis; Otolaryngology; Penicillins; Pharmacology; Research; Respiratory Tract Infections; Rifamycins; Staphylococcus; Streptococcus; Urinary Tract Infections | 1963 |
[USE IN RESPIRATORY INFECTIOUS PATHOLOGY OF A COMBINATION OF DIHYDRONOVOBIOCIN AND ACTIVATED TETRACYCLINE].
Topics: Asthma; Bronchiectasis; Bronchitis; Humans; Novobiocin; Pneumonia; Respiratory Tract Infections; Tetracycline | 1963 |
[Importance of treatment with dihydronovobiocin in infectious pathology].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Humans; Infections; Lung Diseases; Novobiocin; Respiratory Tract Infections; Urinary Tract Infections | 1962 |
[Value of dihydronovobiocin treatment in infectious pathology].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Humans; Infections; Lung Diseases; Novobiocin; Respiratory Tract Infections; Urinary Tract Infections | 1962 |
Novobiocin in allergy.
Topics: Humans; Hypersensitivity; Novobiocin; Respiratory Tract Infections | 1960 |
[Nebulizations with novobiocin in respiratory tract processes].
Topics: Biological Phenomena; Novobiocin; Physiological Phenomena; Respiratory System; Respiratory Tract Infections | 1959 |
Use of a tetracycline phosphate-novobiocin combination in a severe respiratory infection; report of a case.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatologic Agents; Humans; Novobiocin; Phosphates; Protein Synthesis Inhibitors; Respiratory System; Respiratory Tract Infections; Tetracycline | 1958 |