novobiocin and Respiratory-Tract-Infections

novobiocin has been researched along with Respiratory-Tract-Infections* in 13 studies

Reviews

1 review(s) available for novobiocin and Respiratory-Tract-Infections

ArticleYear
[The use of antibiotics in otologic practice].
    Zeitschrift fur arztliche Fortbildung, 1969, Apr-01, Volume: 63, Issue:7

    Topics: Acute Disease; Anti-Bacterial Agents; Bacitracin; Bronchitis; Chloramphenicol; Chronic Disease; Ear Diseases; Humans; Labyrinth Diseases; Laryngitis; Neomycin; Novobiocin; Otitis Externa; Otitis Media; Penicillins; Pneumococcal Infections; Polymyxins; Respiratory Tract Infections; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Tetracycline; Tonsillitis; Tracheal Diseases

1969

Other Studies

12 other study(ies) available for novobiocin and Respiratory-Tract-Infections

ArticleYear
Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents.
    Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9

    Our strategy to combat resistant bacteria consisted of targeting the GyrB/ParE ATP-binding sites located on bacterial DNA gyrase and topoisomerase IV and not utilized by marketed antibiotics. Screening around the minimal ethyl urea binding motif led to the identification of isoquinoline ethyl urea 13 as a promising starting point for fragment evolution. The optimization was guided by structure-based design and focused on antibacterial activity in vitro and in vivo, culminating in the discovery of unprecedented substituents able to interact with conserved residues within the ATP-binding site. A detailed characterization of the lead compound highlighted the potential for treatment of the problematic fluoroquinolone-resistant MRSA, VRE, and S. pneumoniae, and the possibility to offer patients an intravenous-to-oral switch therapy was supported by the identification of a suitable prodrug concept. Eventually, hERG K-channel block was identified as the main limitation of this chemical series, and efforts toward its minimization are reported.

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Drug Discovery; Gram-Negative Bacteria; Half-Life; Hydrogen Bonding; Isoquinolines; Microbial Sensitivity Tests; Potassium Channels; Rats; Respiratory Tract Infections; Solubility; Urea

2017
Efficacy of tetracycline/novobiocin combination against canine upper respiratory infections.
    Veterinary medicine, small animal clinician : VM, SAC, 1980, Volume: 75, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Drug Therapy, Combination; Novobiocin; Respiratory Tract Infections; Tetracyclines

1980
Serological types of Diplococcus pneumoniae strains isolated in Germany. Comparison with type patterns in other countries.
    Medical microbiology and immunology, 1974, Mar-22, Volume: 159, Issue:3

    Topics: Cephaloridine; Chloramphenicol; Drug Combinations; Erythromycin; Fusidic Acid; Germany, West; Humans; Lincomycin; Microbial Sensitivity Tests; Nitrofurans; Novobiocin; Penicillin Resistance; Penicillins; Respiratory Tract Infections; Serotyping; Sputum; Streptococcus pneumoniae; Sulfamethoxazole; Sulfonamides; Tetracycline; Trimethoprim; Vancomycin

1974
[Application of aminodeoxykanamycin (Kanendomycin 'Meiji') in the field of internal medicine].
    The Japanese journal of antibiotics, 1971, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephaloridine; Chloramphenicol; Colistin; Erythromycin; Escherichia coli; Female; Gentamicins; Humans; Kanamycin; Lincomycin; Male; Meningitis; Microbial Sensitivity Tests; Middle Aged; Novobiocin; Penicillins; Radiography; Respiratory Tract Infections; Sepsis; Staphylococcus; Streptococcus; Streptomycin; Sulfonamides; Tetracycline; Urinary Tract Infections

1971
[CLINICAL AND PHARMACOLOGICAL STUDY OF A COMBINATION OF NOVOBIOCIN AND TETRACYCLINE IN PEDIATRICS].
    El Dia medico, 1963, Oct-07, Volume: 35

    Topics: Child; Dermatology; Focal Infection; Focal Infection, Dental; Humans; Infant; Novobiocin; Otitis; Pediatrics; Pharyngitis; Respiratory Tract Infections; Sinusitis; Tetracycline

1963
[KITASAMYCIN. EXPERIMENTAL "IN VITRO" STUDY AND 1ST CLINICAL RESULTS].
    Gazette medicale de France, 1963, Nov-10, Volume: 70

    Topics: Anti-Bacterial Agents; Chlortetracycline; Dermatology; Drug Resistance; Drug Resistance, Microbial; Erythromycin; Gastroenterology; In Vitro Techniques; Kitasamycin; Leukemia; Methicillin; Novobiocin; Osteomyelitis; Otolaryngology; Penicillins; Pharmacology; Research; Respiratory Tract Infections; Rifamycins; Staphylococcus; Streptococcus; Urinary Tract Infections

1963
[USE IN RESPIRATORY INFECTIOUS PATHOLOGY OF A COMBINATION OF DIHYDRONOVOBIOCIN AND ACTIVATED TETRACYCLINE].
    Lyon medical, 1963, Dec-22, Volume: 210

    Topics: Asthma; Bronchiectasis; Bronchitis; Humans; Novobiocin; Pneumonia; Respiratory Tract Infections; Tetracycline

1963
[Importance of treatment with dihydronovobiocin in infectious pathology].
    Gazette medicale de France, 1962, Oct-10, Volume: 69

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Humans; Infections; Lung Diseases; Novobiocin; Respiratory Tract Infections; Urinary Tract Infections

1962
[Value of dihydronovobiocin treatment in infectious pathology].
    Gazette medicale de France, 1962, Oct-10, Volume: 69

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Humans; Infections; Lung Diseases; Novobiocin; Respiratory Tract Infections; Urinary Tract Infections

1962
Novobiocin in allergy.
    Southern medical journal, 1960, Volume: 53

    Topics: Humans; Hypersensitivity; Novobiocin; Respiratory Tract Infections

1960
[Nebulizations with novobiocin in respiratory tract processes].
    La Semana medica, 1959, Jun-18, Volume: 114

    Topics: Biological Phenomena; Novobiocin; Physiological Phenomena; Respiratory System; Respiratory Tract Infections

1959
Use of a tetracycline phosphate-novobiocin combination in a severe respiratory infection; report of a case.
    Antibiotic medicine & clinical therapy (New York, NY), 1958, Volume: 5, Issue:5

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatologic Agents; Humans; Novobiocin; Phosphates; Protein Synthesis Inhibitors; Respiratory System; Respiratory Tract Infections; Tetracycline

1958