novobiocin and Mouth-Neoplasms

novobiocin has been researched along with Mouth-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for novobiocin and Mouth-Neoplasms

Article	Year
Effects of novobiocin on adenovirus DNA synthesis and encapsidation. Nucleic acids research, 1980, Apr-11, Volume: 8, Issue:7 Novobiocin, an inhibitor of DNA gyrase implicated in bacterial and likely mammalian, chromosome replication, inhibited the initiation, but not the elongation of human adenovirus DNA replicative synthesis. The inhibition was partially reversible, even in the presence of protein synthesis inhibitor. Novobiocin inhibited also the encapsidation of viral DNA, and this effect was independent of the block in DNA replication. It was suggested that novobiocin acted on two different functions, one involved in viral DNA replication initiation, the other in DNA encapsidation. Topics: Adenoviruses, Human; Carcinoma; Cell Line; DNA Replication; DNA, Viral; HeLa Cells; Humans; Kinetics; Mouth Neoplasms; Novobiocin; Viral Proteins; Virus Replication	1980

Article

Year

Effects of novobiocin on adenovirus DNA synthesis and encapsidation.

Nucleic acids research, 1980, Apr-11, Volume: 8, Issue:7

Novobiocin, an inhibitor of DNA gyrase implicated in bacterial and likely mammalian, chromosome replication, inhibited the initiation, but not the elongation of human adenovirus DNA replicative synthesis. The inhibition was partially reversible, even in the presence of protein synthesis inhibitor. Novobiocin inhibited also the encapsidation of viral DNA, and this effect was independent of the block in DNA replication. It was suggested that novobiocin acted on two different functions, one involved in viral DNA replication initiation, the other in DNA encapsidation.

Topics: Adenoviruses, Human; Carcinoma; Cell Line; DNA Replication; DNA, Viral; HeLa Cells; Humans; Kinetics; Mouth Neoplasms; Novobiocin; Viral Proteins; Virus Replication

1980