novobiocin has been researched along with Gram-Positive-Bacterial-Infections* in 3 studies
1 trial(s) available for novobiocin and Gram-Positive-Bacterial-Infections
| Article | Year |
|---|---|
Effect of novobiocin-containing antimicrobial regimens on infection and colonization with vancomycin-resistant Enterococcus faecium.
Topics: Drug Resistance, Microbial; Drug Therapy, Combination; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Novobiocin; Vancomycin | 1995 |
2 other study(ies) available for novobiocin and Gram-Positive-Bacterial-Infections
| Article | Year |
|---|---|
Effects of dry cow treatment of beef cows on pathogenic organisms, milk somatic cell counts, and calf growth during the subsequent lactation.
Spring calving Angus and Angus x Hereford multiparous cows were utilized to determine the effects of intramammary treatment with penicillin G procaine (200,000 IU) and novobiocin (400 mg) at the time of weaning on udder health and calf growth after the subsequent calving. Cows were stratified by age and breed and assigned randomly to receive intramammary treatment (n = 99) at weaning or as untreated controls (n = 97). Quarter milk samples were collected at weaning and at 8 to 14 d after calving. Milk samples were analyzed for somatic cell counts (SCC) and mastitis-causing bacteria. Dry cow treatment decreased (P = 0.005) the number of cows infected after calving. Treatment decreased (P = 0.04) the number of cows that developed new infections and reduced (P = 0.03) the number of quarters with mastitis-causing bacteria after calving that were infected at weaning. Somatic cell counts after calving were greatest (P = 0.008) for cows infected with Staphylococcus aureus. Treatment did not alter (P = 0.19) SCC of quarters after calving that were infected with S. aureus at weaning but reduced (P = 0.002) SCC after calving of quarters that were infected with coagulase-negative staphylococci at weaning. Body weight of calves during early lactation was increased (P = 0.006) if cows with intramammary infection were treated at weaning. Treatment of noninfected cows at weaning increased (P = 0.008) adjusted 205-d weaning weights of calves after the subsequent lactation when compared with untreated noninfected cows. We conclude that treatment of beef cows at weaning with intramammary antibiotics decreased intramammary infections after calving, improved udder health during the subsequent lactation, and increased BW gain of the calves. Topics: Animals; Animals, Suckling; Anti-Bacterial Agents; Cattle; Female; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Lactation; Least-Squares Analysis; Mammary Glands, Animal; Mastitis, Bovine; Milk; Novobiocin; Penicillin G Procaine; Random Allocation; Weaning; Weight Gain | 2008 |
Treatment of experimental endocarditis due to multidrug resistant Enterococcus faecium with ciprofloxacin and novobiocin.
The effectiveness of ciprofloxacin and/or novobiocin therapy was assessed for experimental endocarditis caused by three strains of Enterococcus faecium resistant to ampicillin, vancomycin, and aminoglycosides. Rabbits with endocarditis caused by two of the strains had a significant decrease in bacterial counts in vegetations when treated with both antibiotics. Further studies using combination therapy with ciprofloxacin plus novobiocin for multidrug resistant strains of E. faecium are warranted. Topics: Animals; Ciprofloxacin; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecium; Gram-Positive Bacterial Infections; Microbial Sensitivity Tests; Novobiocin; Rabbits | 1994 |