nostocarboline and Disease-Models--Animal

nostocarboline has been researched along with Disease-Models--Animal* in 1 studies

Other Studies

1 other study(ies) available for nostocarboline and Disease-Models--Animal

Article	Year
Potent and selective antiplasmodial activity of the cyanobacterial alkaloid nostocarboline and its dimers. Bioorganic & medicinal chemistry letters, 2008, Aug-01, Volume: 18, Issue:15 The quaternary beta-carbolinium alkaloid nostocarboline from the cyanobacterium Nostoc 78-12A and 10 bis-cationic dimeric derivatives were evaluated against four protozoan parasites and low micromolar values against Trypanosoma brucei, submicromolar values against Leishmania donovani and low nanomolar values against Plasmodium falciparum K1 were determined. Selectivity against rat myoblasts (L6 cells) was found to be up to >2500-fold. Topics: Alkaloids; Animals; Antiprotozoal Agents; Carbolines; Combinatorial Chemistry Techniques; Disease Models, Animal; Leishmania donovani; Malaria; Molecular Structure; Myoblasts; Nostoc; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Trypanosoma	2008

Article

Year

Potent and selective antiplasmodial activity of the cyanobacterial alkaloid nostocarboline and its dimers.

Bioorganic & medicinal chemistry letters, 2008, Aug-01, Volume: 18, Issue:15

The quaternary beta-carbolinium alkaloid nostocarboline from the cyanobacterium Nostoc 78-12A and 10 bis-cationic dimeric derivatives were evaluated against four protozoan parasites and low micromolar values against Trypanosoma brucei, submicromolar values against Leishmania donovani and low nanomolar values against Plasmodium falciparum K1 were determined. Selectivity against rat myoblasts (L6 cells) was found to be up to >2500-fold.

Topics: Alkaloids; Animals; Antiprotozoal Agents; Carbolines; Combinatorial Chemistry Techniques; Disease Models, Animal; Leishmania donovani; Malaria; Molecular Structure; Myoblasts; Nostoc; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Trypanosoma

2008