noscapine and Bronchitis

noscapine has been researched along with Bronchitis* in 6 studies

Trials

2 trial(s) available for noscapine and Bronchitis

Article	Year
[Objectivation of the effect of antitussive agents using tussometry in patients with chronic cough]. Schweizerische medizinische Wochenschrift, 1985, Mar-02, Volume: 115, Issue:9 The antitussive effect of several antitussive agents has been objectively evaluated in patients with chronic stable cough due to bronchial carcinoma, pulmonary tuberculosis or chronic obstructive lung disease. The patients received the active antitussive drugs or placebo in a double-blind, randomized crossover design. The preparations were administered at 10 p.m. and 2 a.m. on 7 consecutive nights and no antitussive was given for the following 20 hours. Cough frequency and intensity were recorded from 10 p.m. until 6 a.m. The active medications were noscapine (30 mg), dextromethorphan (20 mg), dihydrocodeine (30 mg) and codeine (20, 30 and 60 mg) at 10 p.m. and 2 a.m. Cough frequency and intensity were objectively assessed with a pressure transducer placed over the trachea and recorded on a chartrecorder. Statistical analysis was performed with analysis of variance and multiple range testing. Noscapine, dextromethorphan, dihydrocodeine and codeine (60 mg) significantly (p less than 0.001) reduced the cough frequency compared to placebo. They also produced a greater reduction of cough intensity than placebo, codeine (20 mg) and codeine (30 mg) (p less than 0.001). The duration of action of low-dose codeine (6 hours) was unsatisfactory. Subjective preference for dextromethorphan indicates a psychotropic central nervous action of this drug not assessed by the measuring device. Noscapine was equally well tolerated but more neutral psychologically. Topics: Adult; Aged; Antitussive Agents; Bronchitis; Carcinoma, Bronchogenic; Chronic Disease; Clinical Trials as Topic; Codeine; Cough; Dextromethorphan; Double-Blind Method; Humans; Lung Neoplasms; Middle Aged; Noscapine; Tuberculosis, Pulmonary	1985
The use of Duopect as expectorant--antitussive agent. Archivum immunologiae et therapiae experimentalis, 1975, Volume: 23, Issue:1 Topics: Adolescent; Adult; Aged; Asthma; Bronchiectasis; Bronchitis; Chronic Disease; Clinical Trials as Topic; Cough; Drug Evaluation; Drug Tolerance; Female; Guaifenesin; Humans; Male; Middle Aged; Noscapine; Placebos; Tuberculosis	1975

Article

Year

[Objectivation of the effect of antitussive agents using tussometry in patients with chronic cough].

Schweizerische medizinische Wochenschrift, 1985, Mar-02, Volume: 115, Issue:9

The antitussive effect of several antitussive agents has been objectively evaluated in patients with chronic stable cough due to bronchial carcinoma, pulmonary tuberculosis or chronic obstructive lung disease. The patients received the active antitussive drugs or placebo in a double-blind, randomized crossover design. The preparations were administered at 10 p.m. and 2 a.m. on 7 consecutive nights and no antitussive was given for the following 20 hours. Cough frequency and intensity were recorded from 10 p.m. until 6 a.m. The active medications were noscapine (30 mg), dextromethorphan (20 mg), dihydrocodeine (30 mg) and codeine (20, 30 and 60 mg) at 10 p.m. and 2 a.m. Cough frequency and intensity were objectively assessed with a pressure transducer placed over the trachea and recorded on a chartrecorder. Statistical analysis was performed with analysis of variance and multiple range testing. Noscapine, dextromethorphan, dihydrocodeine and codeine (60 mg) significantly (p less than 0.001) reduced the cough frequency compared to placebo. They also produced a greater reduction of cough intensity than placebo, codeine (20 mg) and codeine (30 mg) (p less than 0.001). The duration of action of low-dose codeine (6 hours) was unsatisfactory. Subjective preference for dextromethorphan indicates a psychotropic central nervous action of this drug not assessed by the measuring device. Noscapine was equally well tolerated but more neutral psychologically.

Topics: Adult; Aged; Antitussive Agents; Bronchitis; Carcinoma, Bronchogenic; Chronic Disease; Clinical Trials as Topic; Codeine; Cough; Dextromethorphan; Double-Blind Method; Humans; Lung Neoplasms; Middle Aged; Noscapine; Tuberculosis, Pulmonary

1985

The use of Duopect as expectorant--antitussive agent.

Archivum immunologiae et therapiae experimentalis, 1975, Volume: 23, Issue:1

Topics: Adolescent; Adult; Aged; Asthma; Bronchiectasis; Bronchitis; Chronic Disease; Clinical Trials as Topic; Cough; Drug Evaluation; Drug Tolerance; Female; Guaifenesin; Humans; Male; Middle Aged; Noscapine; Placebos; Tuberculosis

1975

Other Studies

4 other study(ies) available for noscapine and Bronchitis

Article	Year
[Therapeutic activity of an association of a mucolytic drug and a bronchodilator agent in the treatment of respiratory inflammations]. Minerva medica, 1973, Nov-07, Volume: 64, Issue:79 Topics: Bronchiectasis; Bronchitis; Bronchodilator Agents; Bronchopneumonia; Chronic Disease; Cough; Drug Combinations; Expectorants; Guaifenesin; Humans; Lung Abscess; Lung Neoplasms; Noscapine; Respiratory Tract Diseases; Salicylamides; Suppositories; Tracheitis	1973
Safe reduction of the cough reflex with noscapine. A preliminary communication on a new use for an old drug. Anaesthesia, 1969, Volume: 24, Issue:3 Topics: Anesthesia; Bronchitis; Bronchoscopy; Cough; Humans; Noscapine; Respiration	1969
[Therapy of obstructive ventilation disorders]. Praxis, 1968, Nov-12, Volume: 57, Issue:45 Topics: Adult; Asthma; Bronchitis; Humans; Middle Aged; Noscapine; Theophylline	1968
TREATMENT OF BRONCHOSPASTIC STATES IN CHILDREN WITH A THEOPHYLLINE-NOSCAPINE FORMULATION. Clinical medicine (Northfield, Ill.), 1964, Volume: 71 Topics: Asthma; Bronchitis; Chemistry, Pharmaceutical; Child; Delayed-Action Preparations; Humans; Noscapine; Pulmonary Emphysema; Theophylline	1964