Page last updated: 2024-11-01

nortriptyline and Trigeminal Neuralgia

nortriptyline has been researched along with Trigeminal Neuralgia in 2 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Trigeminal Neuralgia: A syndrome characterized by recurrent episodes of excruciating pain lasting several seconds or longer in the sensory distribution of the TRIGEMINAL NERVE. Pain may be initiated by stimulation of trigger points on the face, lips, or gums or by movement of facial muscles or chewing. Associated conditions include MULTIPLE SCLEROSIS, vascular anomalies, ANEURYSMS, and neoplasms. (Adams et al., Principles of Neurology, 6th ed, p187)

Research Excerpts

ExcerptRelevanceReference
" Subjects suffering from traumatic dysesthesia of the trigeminal nerve were treated with capsaicin, a substance P depleter with significant long-term effects."3.69Traumatic dysesthesia of the trigeminal nerve. ( Canavan, D; Graff-Radford, SB; Gratt, BM, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haviv, Y1
Zadik, Y1
Sharav, Y1
Benoliel, R1
Canavan, D1
Graff-Radford, SB1
Gratt, BM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain[NCT02339662]Phase 450 participants (Anticipated)Interventional2015-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for nortriptyline and Trigeminal Neuralgia

ArticleYear
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
    Journal of oral & facial pain and headache, 2014,Winter, Volume: 28, Issue:1

    Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Proto

2014
Traumatic dysesthesia of the trigeminal nerve.
    Journal of orofacial pain, 1994,Fall, Volume: 8, Issue:4

    Topics: Administration, Topical; Aged; Antidepressive Agents, Tricyclic; Capsaicin; Desipramine; Drug Therap

1994