Page last updated: 2024-11-01

nortriptyline and Tinnitus

nortriptyline has been researched along with Tinnitus in 9 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"To determine whether the antidepressant, nortriptyline, is effective for treatment of depression, tinnitus-related disability, and tinnitus symptoms in patients with severe chronic tinnitus."9.07A randomized trial of nortriptyline for severe chronic tinnitus. Effects on depression, disability, and tinnitus symptoms. ( Dobie, R; Katon, W; Russo, J; Sakai, C; Sullivan, M, 1993)
"To determine whether the antidepressant, nortriptyline, is effective for treatment of depression, tinnitus-related disability, and tinnitus symptoms in patients with severe chronic tinnitus."5.07A randomized trial of nortriptyline for severe chronic tinnitus. Effects on depression, disability, and tinnitus symptoms. ( Dobie, R; Katon, W; Russo, J; Sakai, C; Sullivan, M, 1993)
"Ninety-two middle-aged and elderly patients with disabling tinnitus participated in a double-blind randomized clinical trial comparing nortriptyline (a tricyclic antidepressant) to placebo."5.07Antidepressant treatment of tinnitus patients: report of a randomized clinical trial and clinical prediction of benefit. ( Dobie, RA; Katon, WJ; Russo, J; Sakai, CS; Sullivan, MD, 1993)
"This study describes the correlations between several measures of functional disability and Hamilton depression scores in two groups of patients with major depression and depressive symptoms (D-NOS) who were patients enrolled in a 12-week placebo-controlled, double-blind trial of nortriptyline."5.07Depressive symptoms and measures of disability: a prospective study. ( Dobie, R; Katon, W; Russo, J; Sakai, C; Sullivan, M, 1993)
"Antidepressant drugs have been used to treat tinnitus in patients with and without depressive symptoms."2.48Antidepressants for patients with tinnitus. ( Baldo, P; Cecco, S; Doree, C; McFerran, D; Molin, P, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's7 (77.78)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldo, P1
Doree, C1
Molin, P1
McFerran, D1
Cecco, S1
Sullivan, M4
Katon, W3
Russo, J6
Dobie, R4
Sakai, C4
Golden, RN1
Evans, DL1
Dobie, RA3
Sakai, CS3
Sullivan, MD3
Katon, WJ4

Reviews

1 review available for nortriptyline and Tinnitus

ArticleYear
Antidepressants for patients with tinnitus.
    The Cochrane database of systematic reviews, 2012, Sep-12, Issue:9

    Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Nortriptyline; Paroxetine; Randomized Cont

2012

Trials

6 trials available for nortriptyline and Tinnitus

ArticleYear
Coping and marital support as correlates of tinnitus disability.
    General hospital psychiatry, 1994, Volume: 16, Issue:4

    Topics: Adaptation, Psychological; Aged; Depressive Disorder; Disability Evaluation; Double-Blind Method; Fe

1994
A randomized trial of nortriptyline for severe chronic tinnitus. Effects on depression, disability, and tinnitus symptoms.
    Archives of internal medicine, 1993, Oct-11, Volume: 153, Issue:19

    Topics: Aged; Audiometry, Pure-Tone; Chronic Disease; Depression; Depressive Disorder; Disabled Persons; Dou

1993
Antidepressant treatment of tinnitus patients: report of a randomized clinical trial and clinical prediction of benefit.
    The American journal of otology, 1993, Volume: 14, Issue:1

    Topics: Aged; Depressive Disorder; Disabled Persons; Female; Humans; Loudness Perception; Male; Middle Aged;

1993
Depressive symptoms and measures of disability: a prospective study.
    Journal of affective disorders, 1993, Volume: 27, Issue:4

    Topics: Adaptation, Psychological; Aged; Chronic Disease; Depression; Disability Evaluation; Double-Blind Me

1993
Somatization, co-morbidity, and the quality of life: measuring the effect of depression upon chronic medical illness.
    Psychiatric medicine, 1992, Volume: 10, Issue:3

    Topics: Activities of Daily Living; Audiometry, Pure-Tone; Chronic Disease; Comorbidity; Depressive Disorder

1992
Antidepressant treatment of tinnitus patients. Interim report of a randomized clinical trial.
    Acta oto-laryngologica, 1992, Volume: 112, Issue:2

    Topics: Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Hearing Tests; Humans; I

1992

Other Studies

2 other studies available for nortriptyline and Tinnitus

ArticleYear
Antidepressants and tinnitus.
    Archives of internal medicine, 1994, Jun-27, Volume: 154, Issue:12

    Topics: Antidepressive Agents; Depression; Humans; Nortriptyline; Tinnitus

1994
Treatment of depressed tinnitus patients with nortriptyline.
    The Annals of otology, rhinology, and laryngology, 1989, Volume: 98, Issue:11

    Topics: Adolescent; Adult; Aged; Depressive Disorder; Drug Evaluation; Humans; Middle Aged; Nortriptyline; T

1989