Page last updated: 2024-11-01

nortriptyline and Serotonin Syndrome

nortriptyline has been researched along with Serotonin Syndrome in 2 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"As well as neuroleptic malignant syndrome, the SS may cause cerebellar degeneration, probably due to sustained hyperpyrexia."1.31[Progressive cerebellar atrophy following acute antidepressant intoxication]. ( Fujino, Y; Shimoji, E; Takahashi, M; Tsuboi, Y; Yamada, T, 2000)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hinds, NP1
Hillier, CE1
Wiles, CM1
Fujino, Y1
Tsuboi, Y1
Shimoji, E1
Takahashi, M1
Yamada, T1

Other Studies

2 other studies available for nortriptyline and Serotonin Syndrome

ArticleYear
Possible serotonin syndrome arising from an interaction between nortriptyline and selegiline in a lady with parkinsonism.
    Journal of neurology, 2000, Volume: 247, Issue:10

    Topics: Antidepressive Agents, Tricyclic; Antiparkinson Agents; Depressive Disorder; Drug Interactions; Fema

2000
[Progressive cerebellar atrophy following acute antidepressant intoxication].
    Rinsho shinkeigaku = Clinical neurology, 2000, Volume: 40, Issue:10

    Topics: Adult; Antidepressive Agents, Tricyclic; Atrophy; Cerebellar Ataxia; Cerebellum; Female; Humans; Mal

2000