Page last updated: 2024-11-01

nortriptyline and Recrudescence

nortriptyline has been researched along with Recrudescence in 53 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Research Excerpts

ExcerptRelevanceReference
" The investigators studied a patient with a nortriptyline HCI level of 1,205 ng/mL who had four generalized grand mal seizures, each lasting between 60 and 90 seconds that were immediately followed by hypotension requiring norepinephrine support."7.69Recurrent hypotension immediately after seizures in nortriptyline overdose. ( Bell, A; Gaynor, B; Lipper, B, 1994)
" A sustained remission rate of 50% over 2 years in patients with severe major depression who were treated with nortriptyline monotherapy after successful ECT is encouraging."5.69Clinical characteristics associated with relapse 2 years after electroconvulsive therapy for major depression. ( Birkenhäger, TK; Kamperman, AM; Pluijms, EM; Vinther, PT, 2023)
"Data are presented on the baseline characteristics and 2- to 3-year follow-up assessments of placebo-washout responders (PWRs) from a previously reported pharmacokinetically designed double-blind placebo-controlled trial of nortriptyline for major depressive disorder in 6- to 12-year-olds."5.07Baseline and 2- to 3-year follow-up characteristics of placebo-washout responders from the nortriptyline study of depressed 6- to 12-year-olds. ( Cooper, TB; Fox, LW; Garrity, K; Geller, B, 1992)
" Our studies have suggested that older patients appear to benefit as much, though perhaps more slowly, than mid-life patients from acute combined treatment (nortriptyline+interpersonal psychotherapy) of major depression."4.79Treatment of major depression in later life: a life cycle perspective. ( Reynolds, CF, 1997)
"Nortriptyline and VEN were equally effective in prolonging remission, although relapse rates after ECT are substantial despite intensive pharmacology."3.87Pharmacological strategies in the prevention of relapse after electroconvulsive therapy. ( Cooper, T; Haskett, RF; Isenberg, K; McCall, WV; Mulsant, BH; Prudic, J; Rosenquist, PB; Sackeim, HA, 2013)
" The investigators studied a patient with a nortriptyline HCI level of 1,205 ng/mL who had four generalized grand mal seizures, each lasting between 60 and 90 seconds that were immediately followed by hypotension requiring norepinephrine support."3.69Recurrent hypotension immediately after seizures in nortriptyline overdose. ( Bell, A; Gaynor, B; Lipper, B, 1994)
"Patients with major depressive disorder and an indication for ECT received either nortriptyline or placebo during a bilateral ECT course."3.11Influence of adjuvant nortriptyline on the efficacy of electroconvulsive therapy: A randomized controlled trial and 1-year follow-up. ( Birkenhäger, TK; Hoogendijk, WJG; Kamperman, AM; Pluijms, EM; van den Broek, WW, 2022)
"Relapse was assessed with the 24-item Hamilton Rating Scale for Depression."2.74Is baseline medication resistance associated with potential for relapse after successful remission of a depressive episode with ECT? Data from the Consortium for Research on Electroconvulsive Therapy (CORE). ( Bailine, SH; Fink, M; Husain, MM; Kellner, CH; Knapp, RG; Mueller, M; Petrides, G; Rasmussen, KG; Rummans, TA; Sampson, SM, 2009)
"It suggests that successfully treating depression in PD leads to important, sustained improvements in these outcomes and that patients who improve on antidepressants are less likely to relapse than are patients who initially improve on placebo."2.74The impact of treatment of depression on quality of life, disability and relapse in patients with Parkinson's disease. ( Bienfait, K; Buyske, S; Dicke, A; Dobkin, RD; Gara, M; Marin, H; Mark, MH; Menza, M, 2009)
"Subjects had only recurrent, unipolar depression."2.70Initial recovery patterns may predict which maintenance therapies for depression will keep older adults well. ( Begley, A; Dew, MA; Frank, E; Houck, PR; Kupfer, DJ; Mazumdar, S; Mulsant, B; Reynolds, CF, 2001)
"The time to recurrence of a major depressive episode for all 3 active treatments was significantly better than for placebo."2.69Nortriptyline and interpersonal psychotherapy as maintenance therapies for recurrent major depression: a randomized controlled trial in patients older than 59 years. ( Cornes, C; Dew, MA; Frank, E; Houck, PR; Imber, SD; Kupfer, DJ; Mazumdar, S; Miller, MD; Perel, JM; Pollock, BG; Reynolds, CF; Stack, JA, 1999)
"These mothers are apprehensive about recurrence after later births."2.67Prevention of recurrent postpartum major depression. ( Wheeler, SB; Wisner, KL, 1994)
"Mean survival time without recurrence is 21."2.66Open-trial maintenance pharmacotherapy in late-life depression: survival analysis. ( Cornes, C; Frank, E; Imber, S; Kupfer, DJ; Morycz, RK; Perel, JM; Reynolds, CF; Thornton, J, 1989)
"Headaches are a common entity in the ambulatory population."2.40Diagnosis, prophylaxis, and treatment of headaches in the athlete. ( Kaplan, B; Swain, RA, 1997)
"Major depressive disorder is associated with increased cardiac mortality."1.36Reduced cardio-respiratory coupling after treatment with nortriptyline in contrast to S-citalopram. ( Bär, KJ; Höfels, S; Maier, W; Schuhmacher, A; Schulz, S; Voss, A; Yeragani, VK; Zobel, A, 2010)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199011 (20.75)18.7374
1990's23 (43.40)18.2507
2000's13 (24.53)29.6817
2010's4 (7.55)24.3611
2020's2 (3.77)2.80

Authors

AuthorsStudies
Pluijms, EM2
Kamperman, AM2
Hoogendijk, WJG1
van den Broek, WW1
Birkenhäger, TK2
Vinther, PT1
van Eerd, EAM1
van Schayck, OCP1
Wesseling, G1
Kotz, D1
Rasmussen, KG1
Mueller, M1
Rummans, TA1
Husain, MM1
Petrides, G1
Knapp, RG1
Fink, M1
Sampson, SM1
Bailine, SH1
Kellner, CH1
Menza, M1
Dobkin, RD1
Marin, H1
Mark, MH1
Gara, M1
Buyske, S1
Bienfait, K1
Dicke, A1
Uher, R1
Muthén, B1
Souery, D1
Mors, O1
Jaracz, J1
Placentino, A1
Petrovic, A1
Zobel, A2
Henigsberg, N1
Rietschel, M1
Aitchison, KJ1
Farmer, A1
McGuffin, P1
Bär, KJ1
Schuhmacher, A1
Höfels, S1
Schulz, S1
Voss, A1
Yeragani, VK1
Maier, W1
Prudic, J2
Haskett, RF2
McCall, WV1
Isenberg, K1
Cooper, T1
Rosenquist, PB1
Mulsant, BH4
Sackeim, HA2
Morse, JQ1
Pilkonis, PA1
Houck, PR9
Frank, E14
Reynolds, CF19
Pilhatsch, MK1
Burghardt, R1
Wandinger, KP1
Bauer, M1
Adli, M1
Serra, M1
Gastó, C1
Navarro, V1
Torres, X1
Blanch, J1
Masana, G1
Dirks, AC1
van Hyfte, DM1
Bialos, D2
Giller, E2
Jatlow, P2
Docherty, J1
Harkness, L2
Stack, JA3
Paradis, CF1
Anderson, B1
Mayo, AL1
Miller, MD10
Rifai, AH4
Perel, JM10
Wisner, KL1
Wheeler, SB1
George, CJ3
Mann, JJ2
Cornes, C7
Pollock, BG5
Mazumdar, S12
Lipper, B1
Bell, A1
Gaynor, B1
Stokes, PE1
Hambrecht, M1
Dew, MA7
Begley, A2
Hall, M2
Mulsant, B2
Shear, MK1
Kupfer, DJ8
Pasternak, RE1
Prigerson, H1
Fasiczka, A1
Byrne, S1
Rothschild, AJ1
Swain, RA1
Kaplan, B1
Begley, AE3
Little, JT1
Imber, SD2
Miller, M2
Flint, AJ3
Rifat, SL3
Alexopoulos, GS1
Meyers, BS1
Young, RC1
Kalayam, B1
Kakuma, T1
Gabrielle, M1
Sirey, JA1
Hull, J1
Bump, GM1
Thase, ME1
Pettinati, HM1
Greenberg, RM1
Crowe, RR1
Cooper, TB4
Szanto, K1
Furlong, FW1
Sellers, EM1
Kapur, BM1
Hansen, CE2
Baastrup, PC1
Hvidberg, EF2
Seth, R1
Jennings, AL1
Bindman, J1
Phillips, J1
Bergmann, K1
Morycz, RK2
Geller, B1
Fox, LW1
Garrity, K1
Scott, AI1
Weeks, DJ1
McDonald, CF1
Hoch, CC1
Buysse, DJ1
Rifai, H1
Imber, S2
Thornton, J1
Georgotas, A2
McCue, RE2
Nagachandran, N1
Chang, I1
Waldo, M1
Simons, AD1
Murphy, GE1
Levine, JL1
Wetzel, RD1
Chisholm, DD1
Kragh-Sorensen, P1
Larsen, NE1
Nasestoft, J1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Exploring Alterations of Central Autonomic Modulation in Patients With Bipolar Depression[NCT01213121]Phase 460 participants (Anticipated)Interventional2010-09-30Recruiting
Measurement of GABA and Neurosteroid Levels in Women With Menopausal Major Depression Before and After Treatment With Estrogen Alone, Fluoxetine Alone, or Estrogen and Fluoxetine and Normal Controls Before and After Treatment With Estrogen[NCT00626340]Phase 418 participants (Actual)Interventional1999-07-31Completed
A Prospective Study of Pregnant and Postpartum Women With and Without Mood Disorders[NCT03615794]400 participants (Anticipated)Observational2017-10-01Recruiting
Adapting Marital Therapy in Older Adults With Depression[NCT00612807]Phase 1/Phase 242 participants (Actual)Interventional2006-07-31Completed
Randomised Controlled Trial of Electroconvulsive Therapy (ECT) With Pharmacotherapy or Pharmacotherapy Alone in Relapse Prevention of Depression[NCT00627887]Phase 456 participants (Actual)Interventional2008-01-31Completed
Optimization of Electroconvulsive Therapy[NCT00045916]Phase 4340 participants (Actual)Interventional2001-02-28Completed
Phase 1 Study: Evaluation of Three Continuation Therapies After Acute Electroconvusive Therapy (ECT) Concerning Efficacy and Cognition in Severly Depressed Patients[NCT00437385]Phase 190 participants (Actual)Interventional2005-03-31Completed
Relapse Prevention in Patients With a Major Depressive Episode Treated With Electroconvulsive Treatment Using a Fixed Dose Range of Escitalopram Compared to a Fixed Dose of Nortriptyline (DUAG-7) A Randomised Controlled 6 Month Double-blind Study[NCT00660062]Phase 447 participants (Actual)Interventional2009-08-31Terminated (stopped due to Slow inclusion)
Prolonging Remission in Depressed Elderly (PRIDE)[NCT01028508]Phase 4247 participants (Actual)Interventional2010-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Comparison of Cortical GABA Levels in 4 Groups of Subjects Using Estrogen Alone, Fluoxetine Alone, Estrogen and Fluoxetine Combined in Pre and Post 4.0T Magnetic Resonance Spectroscopy Sessions.

"This study was conducted at Yale University almost two decades ago. Our group at the University of Pennsylvania only has very basic information about this study. This includes the number of participants, which was 18, and the fact that no adverse events occurred. Staff members at the University of Pennsylvania do not have access to any additional study data. The contact person who initially entered this study protocol information is no longer at the University of Pennsylvania and we are unable to contact for additional information.~We only know that 18 participants completed, but as far as we know data was never analyzed for these 18 participants." (NCT00626340)
Timeframe: Healthy controls will undergo scans pre and post 3 weeks of estrogen treatment. Women with depression will undergo scans pre and post 6 weeks of treatment with estrogen alone, estrogen and fluoxetine, or fluoxetine alone

Intervention ()
All Participants0

Dyadic Adjustment Scale (DAS)

The DAS is a self-report measure of marital adjustment that includes questions about agreement on lifestyle and household decisions, level of conflict, level of cooperation, and affection. Scores range from 0 to 151, with higher scores representing better relationship functioning. (NCT00612807)
Timeframe: pre-treatment, monthly, post-treatment, 6 month follow-up

,
InterventionScore on DAS measure (Mean)
Baseline assessment (Depressed spouse)Post-test assessment (Depressed spouse)Follow-up assessment (Depressed spouse)Baseline assessment (Non-depressed spouse)Post-test assessment (Non-depressed spouse)Follow-up assessment (Non-depressed spouse)
Semi-weekly Medication Management72.1484.1789.6791.093.33104.17
Semi-weekly Medication Management + Weekly Marital Therapy84.4392.2791.0788.2997.5798.31

Hamilton Depression Rating Scale (HDRS)

The HDRS is a semi-structured interview administered by a trained independent evaluator, and used for rating the severity of depressive symptoms. Scores range from 0 to 50, with higher scores indicating greater severity of depression. (NCT00612807)
Timeframe: pre-treatment, monthly, post-treatment, 6 month follow-up

,
InterventionScore on HDRS (Mean)
Baseline assessment (Depressed spouse)Post-test assessment (Depressed spouse)Follow-up assessment (Depressed spouse)Baseline assessment (Non-depressed spouse)Post-test assessment (Non-depressed spouse)Follow-up assessment (Non-depressed spouse)
Semi-weekly Medication Management17.865.009.175.145.333.83
Semi-weekly Medication Management + Weekly Marital Therapy19.07.298.148.863.295.71

Reviews

4 reviews available for nortriptyline and Recrudescence

ArticleYear
Pharmacological strategies in the prevention of relapse after electroconvulsive therapy.
    The journal of ECT, 2013, Volume: 29, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohex

2013
A primary care perspective on management of acute and long-term depression.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Acute Disease; Adult; Aged; Depressive Disorder; Drug Administration Schedule; Drug Therapy, Combina

1993
Treatment of major depression in later life: a life cycle perspective.
    The Psychiatric quarterly, 1997,Fall, Volume: 68, Issue:3

    Topics: Aged; Antidepressive Agents; Anxiety; Bereavement; Clinical Trials as Topic; Combined Modality Thera

1997
Diagnosis, prophylaxis, and treatment of headaches in the athlete.
    Southern medical journal, 1997, Volume: 90, Issue:9

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic;

1997

Trials

32 trials available for nortriptyline and Recrudescence

ArticleYear
Influence of adjuvant nortriptyline on the efficacy of electroconvulsive therapy: A randomized controlled trial and 1-year follow-up.
    Acta psychiatrica Scandinavica, 2022, Volume: 145, Issue:5

    Topics: Depressive Disorder, Major; Electroconvulsive Therapy; Follow-Up Studies; Humans; Nortriptyline; Rec

2022
Clinical characteristics associated with relapse 2 years after electroconvulsive therapy for major depression.
    Acta psychiatrica Scandinavica, 2023, Volume: 147, Issue:6

    Topics: Antidepressive Agents; Depression; Depressive Disorder, Major; Electroconvulsive Therapy; Humans; No

2023
Predictors of long-term smoking cessation in patients with COPD: results from a randomised controlled trial.
    The European respiratory journal, 2017, Volume: 49, Issue:6

    Topics: Aged; Female; Humans; Male; Middle Aged; Nortriptyline; Patient Participation; Prevalence; Pulmonary

2017
Is baseline medication resistance associated with potential for relapse after successful remission of a depressive episode with ECT? Data from the Consortium for Research on Electroconvulsive Therapy (CORE).
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:2

    Topics: Adult; Aged; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Drug Resi

2009
The impact of treatment of depression on quality of life, disability and relapse in patients with Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Jul-15, Volume: 24, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depression; Disability Evaluation; Double-Bli

2009
Trajectories of change in depression severity during treatment with antidepressants.
    Psychological medicine, 2010, Volume: 40, Issue:8

    Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder; Europe; Female; Follow-Up Studies; Ge

2010
Pharmacological strategies in the prevention of relapse after electroconvulsive therapy.
    The journal of ECT, 2013, Volume: 29, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohex

2013
Impact of cluster C personality disorders on outcomes of acute and maintenance treatment in late-life depression.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:9

    Topics: Activities of Daily Living; Acute Disease; Aged; Antidepressive Agents, Tricyclic; Cluster Analysis;

2005
[Maintenance electroconvulsive therapy in elderly psychotic unipolar depression].
    Medicina clinica, 2006, Apr-08, Volume: 126, Issue:13

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Electroconvulsive Therapy; Femal

2006
Recurrence of depression after discontinuation of long-term amitriptyline treatment.
    The American journal of psychiatry, 1982, Volume: 139, Issue:3

    Topics: Adult; Aged; Amitriptyline; Depressive Disorder; Female; Humans; Long-Term Care; Male; Middle Aged;

1982
Prevention of recurrent postpartum major depression.
    Hospital & community psychiatry, 1994, Volume: 45, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder; Female; Humans; Nortriptyline; Odds Ratio; Pregnancy; Ps

1994
Prevention of recurrent postpartum major depression.
    Hospital & community psychiatry, 1994, Volume: 45, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder; Female; Humans; Nortriptyline; Odds Ratio; Pregnancy; Ps

1994
Prevention of recurrent postpartum major depression.
    Hospital & community psychiatry, 1994, Volume: 45, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder; Female; Humans; Nortriptyline; Odds Ratio; Pregnancy; Ps

1994
Prevention of recurrent postpartum major depression.
    Hospital & community psychiatry, 1994, Volume: 45, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder; Female; Humans; Nortriptyline; Odds Ratio; Pregnancy; Ps

1994
Treatment of consecutive episodes of major depression in the elderly.
    The American journal of psychiatry, 1994, Volume: 151, Issue:12

    Topics: Age Factors; Aged; Combined Modality Therapy; Depressive Disorder; Female; Humans; Male; Middle Aged

1994
High relapse rate after discontinuation of adjunctive medication for elderly patients with recurrent major depression.
    The American journal of psychiatry, 1996, Volume: 153, Issue:11

    Topics: Age Factors; Age of Onset; Aged; Antidepressive Agents; Combined Modality Therapy; Depressive Disord

1996
The posttreatment illness course of depression in bereaved elders. High relapse/recurrence rates.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1997,Winter, Volume: 5, Issue:1

    Topics: Aged; Antidepressive Agents, Tricyclic; Bereavement; Combined Modality Therapy; Depressive Disorder;

1997
How common is resistance to treatment in recurrent, nonpsychotic geriatric depression?
    The American journal of psychiatry, 1998, Volume: 155, Issue:8

    Topics: Academic Medical Centers; Aged; Antidepressive Agents; Combined Modality Therapy; Depressive Disorde

1998
Nortriptyline and interpersonal psychotherapy as maintenance therapies for recurrent major depression: a randomized controlled trial in patients older than 59 years.
    JAMA, 1999, Jan-06, Volume: 281, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Dep

1999
Treatment of 70(+)-year-olds with recurrent major depression. Excellent short-term but brittle long-term response.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1999,Winter, Volume: 7, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Chi-Square Distribution; Com

1999
Recurrence of first-episode geriatric depression after discontinuation of maintenance antidepressants.
    The American journal of psychiatry, 1999, Volume: 156, Issue:6

    Topics: Aged; Antidepressive Agents; Depressive Disorder; Female; Follow-Up Studies; Humans; Male; Middle Ag

1999
The art of clinical management in pharmacologic trials with depressed elderly patients: lessons from the Pittsburgh Study of Maintenance Therapies in Late-Life Depression.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1999,Summer, Volume: 7, Issue:3

    Topics: Aged; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder, Major; Double

1999
Executive dysfunction and long-term outcomes of geriatric depression.
    Archives of general psychiatry, 2000, Volume: 57, Issue:3

    Topics: Age Factors; Aged; Antidepressive Agents, Tricyclic; Cognition Disorders; Depressive Disorder; Femal

2000
Paroxetine versus nortriptyline in the continuation and maintenance treatment of depression in the elderly.
    Depression and anxiety, 2001, Volume: 13, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Aged; Depressive Disorder, Major; Double-Blind Method; Female; Follow-

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; E

2001
Initial recovery patterns may predict which maintenance therapies for depression will keep older adults well.
    Journal of affective disorders, 2001, Volume: 65, Issue:2

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Depressive Dis

2001
Combined pharmacotherapy and psychotherapy in the acute and continuation treatment of elderly patients with recurrent major depression: a preliminary report.
    The American journal of psychiatry, 1992, Volume: 149, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Combined Modality Therapy; Depressive Disorde

1992
Baseline and 2- to 3-year follow-up characteristics of placebo-washout responders from the nortriptyline study of depressed 6- to 12-year-olds.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1992, Volume: 31, Issue:4

    Topics: Bipolar Disorder; Child; Depressive Disorder; Female; Follow-Up Studies; Humans; Longitudinal Studie

1992
Sleep in late-life recurrent depression. Changes during early continuation therapy with nortriptyline.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1991, Volume: 5, Issue:2

    Topics: Aged; Aged, 80 and over; Depressive Disorder; Double-Blind Method; Electroencephalography; Female; H

1991
Open-trial maintenance pharmacotherapy in late-life depression: survival analysis.
    Psychiatry research, 1989, Volume: 27, Issue:3

    Topics: Aged; Clinical Trials as Topic; Depressive Disorder; Female; Follow-Up Studies; Humans; Long-Term Ca

1989
A placebo-controlled comparison of nortriptyline and phenelzine in maintenance therapy of elderly depressed patients.
    Archives of general psychiatry, 1989, Volume: 46, Issue:9

    Topics: Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Nort

1989
How effective and safe is continuation therapy in elderly depressed patients? Factors affecting relapse rate.
    Archives of general psychiatry, 1988, Volume: 45, Issue:10

    Topics: Age Factors; Aged; Depressive Disorder; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nortri

1988
Long-term amitriptyline in chronic depression.
    The Hillside journal of clinical psychiatry, 1985, Volume: 7, Issue:1

    Topics: Amitriptyline; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method;

1985
Cognitive therapy and pharmacotherapy for depression. Sustained improvement over one year.
    Archives of general psychiatry, 1986, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Attitude; Behavior Therapy; Cognition; Combined Modality Therapy; Depressive Diso

1986
Long-term treatment of endogenous depression with nortriptyline with control of plasma levels.
    Psychological medicine, 1974, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Blood Specimen Collection; Chromatography, Gas; Clinical

1974

Other Studies

18 other studies available for nortriptyline and Recrudescence

ArticleYear
Reduced cardio-respiratory coupling after treatment with nortriptyline in contrast to S-citalopram.
    Journal of affective disorders, 2010, Volume: 127, Issue:1-3

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Depre

2010
Augmentation with atomoxetine in treatment-resistant depression with psychotic features. A case report.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:2

    Topics: Atomoxetine Hydrochloride; Clozapine; Depressive Disorder, Major; Drug Therapy, Combination; Female;

2006
Recurrent hyponatremia after substitution of citalopram with duloxetine.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:3

    Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Citalopram; Depression; Duloxetine Hydrochlorid

2007
Does recruitment method make a difference? Effects on protocol retention and treatment outcome in elderly depressed patients.
    Psychiatry research, 1995, Jan-31, Volume: 56, Issue:1

    Topics: Adjustment Disorders; Aged; Bias; Combined Modality Therapy; Depressive Disorder; Female; Humans; Li

1995
Hopelessness in suicide attempters after acute treatment of major depression in late life.
    The American journal of psychiatry, 1994, Volume: 151, Issue:11

    Topics: Age Factors; Aged; Depressive Disorder; Female; Follow-Up Studies; Geriatric Assessment; Humans; Mal

1994
Recurrent hypotension immediately after seizures in nortriptyline overdose.
    The American journal of emergency medicine, 1994, Volume: 12, Issue:4

    Topics: Biological Availability; Blood Pressure; Drug Overdose; Female; Heart; Humans; Hypotension; Midazola

1994
[Toxic tricyclic drug plasma level caused by fluoxetine].
    Psychiatrische Praxis, 1995, Volume: 22, Issue:6

    Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressiv

1995
Psychiatrists' responses to failure of maintenance therapy with antidepressants.
    Psychiatric services (Washington, D.C.), 1997, Volume: 48, Issue:6

    Topics: 1-Naphthylamine; Adult; Antidepressive Agents; Attitude of Health Personnel; Depressive Disorder; Do

1997
Effects of age at onset of first lifetime episode of recurrent major depression on treatment response and illness course in elderly patients.
    The American journal of psychiatry, 1998, Volume: 155, Issue:6

    Topics: Age Factors; Age of Onset; Aged; Combined Modality Therapy; Depressive Disorder; Female; Humans; Lif

1998
Maintenance treatment for recurrent depression in late life. A four-year outcome study.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2000,Spring, Volume: 8, Issue:2

    Topics: Aged; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Drug Therapy, Co

2000
Nonresponse to first-line pharmacotherapy may predict relapse and recurrence of remitted geriatric depression.
    Depression and anxiety, 2001, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorde

2001
Treatment outcome in suicidal vs. non-suicidal elderly patients.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2001,Summer, Volume: 9, Issue:3

    Topics: Aged; Antidepressive Agents; Anxiety Disorders; Depressive Disorder, Major; Female; Humans; Male; No

2001
Amitriptyline blood levels and relapse.
    Canadian Psychiatric Association journal, 1977, Volume: 22, Issue:6

    Topics: Administration, Oral; Adult; Amitriptyline; Bipolar Disorder; Double-Blind Method; Female; Follow-Up

1977
Therapeutic control of plasma concentrations and long-term effect of nortriptyline in recurrent affective disorders.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1976, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Depression; Female; Humans; Male; Middle Aged; Nortriptyli

1976
Combination treatment with noradrenalin and serotonin reuptake inhibitors in resistant depression.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 161

    Topics: 1-Naphthylamine; Adult; Aged; Aged, 80 and over; Depressive Disorder; Drug Therapy, Combination; Fem

1992
Continuation electroconvulsive therapy: preliminary guidelines and an illustrative case report.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Aged; Combined Modality Therapy; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Nor

1991
Open-trial maintenance nortriptyline in geriatric depression: survival analysis and preliminary data on the use of REM latency as a predictor of recurrence.
    Psychopharmacology bulletin, 1989, Volume: 25, Issue:1

    Topics: Aged; Depressive Disorder; Humans; Nortriptyline; Recurrence; Sleep, REM

1989
Change in serum antidepressant level at a constant dose of medication.
    The American journal of psychiatry, 1986, Volume: 143, Issue:3

    Topics: Depressive Disorder; Drug Tolerance; Female; Humans; Middle Aged; Nortriptyline; Recurrence

1986