Page last updated: 2024-11-01

nortriptyline and Pulmonary Disease, Chronic Obstructive

nortriptyline has been researched along with Pulmonary Disease, Chronic Obstructive in 13 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.

Research Excerpts

ExcerptRelevanceReference
"Bupropion SR treatment is an efficacious aid to smoking cessation in patients with COPD."9.11Efficacy of bupropion and nortriptyline for smoking cessation among people at risk for or with chronic obstructive pulmonary disease. ( Huibers, MJ; Knipschild, PG; van Schayck, CP; Wagena, EJ; Wouters, EF, 2005)
"A total of 255 participants, aged 30-70 years, received smoking cessation counselling and were assigned bupropion, nortriptyline or placebo randomly for 12 weeks."5.14The cost-effectiveness of antidepressants for smoking cessation in chronic obstructive pulmonary disease (COPD) patients. ( Kaper, J; Severens, JL; Van Schayck, CP; Wagena, EJ; Wouters, EF, 2009)
"The study design is a randomized controlled trial comparing confrontational counselling delivered by a respiratory nurse combined with nortriptyline for smoking cessation (experimental group), health education and promotion delivered by a respiratory nurse combined with nortriptyline for smoking cessation (control group 1), and "care as usual" delivered by the GP (control group 2)."5.12Efficacy of confrontational counselling for smoking cessation in smokers with previously undiagnosed mild to moderate airflow limitation: study protocol of a randomized controlled trial. ( Huibers, MJ; Kotz, D; van Schayck, OC; Wesseling, G, 2007)
"Bupropion SR treatment is an efficacious aid to smoking cessation in patients with COPD."5.11Efficacy of bupropion and nortriptyline for smoking cessation among people at risk for or with chronic obstructive pulmonary disease. ( Huibers, MJ; Knipschild, PG; van Schayck, CP; Wagena, EJ; Wouters, EF, 2005)
"However, this major comorbidity in COPD is rarely managed effectively."2.58Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease. ( Carson-Chahhoud, KV; Pollok, J; van Agteren, JE, 2018)
"Patients with COPD show higher nicotine dependence and seem to have greater difficulty in quitting smoking."2.47[Smoking in COPD]. ( Bernabé Barrios, MJ; Rodríguez Hermosa, JL; Santamaría Rodríguez, B; Zamarro García, C, 2011)
"Optimization of NRT is of importance in COPD patients because they may be more nicotine dependent and have more difficulties to quit than smokers without COPD."2.45Therapeutic strategies to optimize the efficacy of nicotine replacement therapies. ( Berlin, I, 2009)
"Pretreatment with nortriptyline inhibited pAkt induced by CSE and H(2)O(2) as well as restored HDAC activity that had been decreased by H(2)O(2) and CSE."1.37Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ. ( Barnes, PJ; Ito, K; Mercado, N; To, Y, 2011)
"Rehabilitation of COPD-patients is an important part of the therapeutic management."1.33[COPD-rehabilitation]. ( Lichtenschopf, A; Zwick, H, 2005)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (53.85)29.6817
2010's4 (30.77)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Kadushkin, A1
Tahanovich, A1
Movchan, L1
Levandovskaya, O1
Shman, T1
Kadushkin, AG1
Tahanovich, AD1
Movchan, LV1
Kolesnikova, TS1
Khadasouskaya, EV1
Shman, TV1
van Eerd, EAM1
van Schayck, OCP1
Wesseling, G3
Kotz, D3
Pollok, J1
van Agteren, JE1
Carson-Chahhoud, KV1
Huibers, MJ3
van Schayck, OC2
Bredesen, H1
Lous, J1
Berlin, I1
Van Schayck, CP2
Kaper, J1
Wagena, EJ2
Wouters, EF2
Severens, JL1
Mercado, N1
To, Y1
Ito, K1
Barnes, PJ1
Zamarro García, C1
Bernabé Barrios, MJ1
Santamaría Rodríguez, B1
Rodríguez Hermosa, JL1
Zwick, H1
Lichtenschopf, A1
Knipschild, PG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
In-patient Smoking Cessation Intervention Using Counseling, Spirometry and Nicotine Replacement Therapy[NCT02470923]90 participants (Anticipated)Interventional2015-08-31Recruiting
"Effectiveness of the Evaluation and Communication of Pulmonary Age as Help for Smoking Cessation: a Cluster Randomized Essay"[NCT04276116]800 participants (Anticipated)Interventional2023-03-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for nortriptyline and Pulmonary Disease, Chronic Obstructive

ArticleYear
Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease.
    The Cochrane database of systematic reviews, 2018, 12-19, Volume: 12

    Topics: Antidepressive Agents, Tricyclic; Depression; Dizziness; Dyspnea; Exercise Tolerance; Forced Expirat

2018
Therapeutic strategies to optimize the efficacy of nicotine replacement therapies.
    COPD, 2009, Volume: 6, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Antidepressive Agents, Second-Generation; Antidepre

2009
[Smoking in COPD].
    Archivos de bronconeumologia, 2011, Volume: 47 Suppl 8

    Topics: Benzazepines; Bupropion; Clonidine; Comorbidity; Disease Progression; Europe; Humans; Motivation; Ni

2011

Trials

5 trials available for nortriptyline and Pulmonary Disease, Chronic Obstructive

ArticleYear
Predictors of long-term smoking cessation in patients with COPD: results from a randomised controlled trial.
    The European respiratory journal, 2017, Volume: 49, Issue:6

    Topics: Aged; Female; Humans; Male; Middle Aged; Nortriptyline; Patient Participation; Prevalence; Pulmonary

2017
Efficacy of confronting smokers with airflow limitation for smoking cessation.
    The European respiratory journal, 2009, Volume: 33, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Counseling; Female; Humans; Logistic Models; Male; Middle

2009
Efficacy of confronting smokers with airflow limitation for smoking cessation.
    The European respiratory journal, 2009, Volume: 33, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Counseling; Female; Humans; Logistic Models; Male; Middle

2009
Efficacy of confronting smokers with airflow limitation for smoking cessation.
    The European respiratory journal, 2009, Volume: 33, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Counseling; Female; Humans; Logistic Models; Male; Middle

2009
Efficacy of confronting smokers with airflow limitation for smoking cessation.
    The European respiratory journal, 2009, Volume: 33, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Counseling; Female; Humans; Logistic Models; Male; Middle

2009
The cost-effectiveness of antidepressants for smoking cessation in chronic obstructive pulmonary disease (COPD) patients.
    Addiction (Abingdon, England), 2009, Volume: 104, Issue:12

    Topics: Adult; Aged; Antidepressive Agents; Bupropion; Confidence Intervals; Cost-Benefit Analysis; Cotinine

2009
Efficacy of bupropion and nortriptyline for smoking cessation among people at risk for or with chronic obstructive pulmonary disease.
    Archives of internal medicine, 2005, Oct-24, Volume: 165, Issue:19

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Depression; D

2005
Efficacy of confrontational counselling for smoking cessation in smokers with previously undiagnosed mild to moderate airflow limitation: study protocol of a randomized controlled trial.
    BMC public health, 2007, Nov-15, Volume: 7

    Topics: Adrenergic Uptake Inhibitors; Combined Modality Therapy; Counseling; Humans; Nortriptyline; Patient

2007

Other Studies

5 other studies available for nortriptyline and Pulmonary Disease, Chronic Obstructive

ArticleYear
Nortriptyline enhances corticosteroid sensitivity of blood T cells from patients with chronic obstructive pulmonary disease.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2021, Volume: 72, Issue:5

    Topics: Adrenal Cortex Hormones; Humans; Leukocytes, Mononuclear; Nortriptyline; Pulmonary Disease, Chronic

2021
Nortriptyline Modulates the Migration of Peripheral Blood Lymphocytes and Monocytes in Patients with Chronic Obstructive Pulmonary Disease.
    Doklady. Biochemistry and biophysics, 2022, Volume: 507, Issue:1

    Topics: Budesonide; Chemokines; Humans; Killer Cells, Natural; Monocytes; Nortriptyline; Pulmonary Disease,

2022
[Smoking cessation with special focus on primary health care].
    Ugeskrift for laeger, 2009, Feb-23, Volume: 171, Issue:9

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Cardiovascula

2009
Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 337, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenergic Uptake Inhibitors; Anti-Inflammatory Agents; Budesonide; Cells,

2011
[COPD-rehabilitation].
    Wiener medizinische Wochenschrift (1946), 2005, Volume: 155, Issue:5-6

    Topics: Acupuncture Therapy; Adrenergic alpha-Agonists; Antidepressive Agents, Second-Generation; Antidepres

2005