Page last updated: 2024-11-01

nortriptyline and Puerperal Disorders

nortriptyline has been researched along with Puerperal Disorders in 5 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Puerperal Disorders: Disorders or diseases associated with PUERPERIUM, the six-to-eight-week period immediately after PARTURITION in humans.

Research Excerpts

ExcerptRelevanceReference
"These mothers are apprehensive about recurrence after later births."2.67Prevention of recurrent postpartum major depression. ( Wheeler, SB; Wisner, KL, 1994)
"Nortriptyline was not detected in the infants' sera."1.28Serum nortriptyline levels in nursing mothers and their infants. ( Perel, JM; Wisner, KL, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PELZMAN, O1
Brixen-Rasmussen, L1
Halgrener, J1
Jørgensen, A1
Wisner, KL2
Wheeler, SB1
Perel, JM1
Matheson, I1
Skjaeraasen, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Measurement of GABA and Neurosteroid Levels in Women With Menopausal Major Depression Before and After Treatment With Estrogen Alone, Fluoxetine Alone, or Estrogen and Fluoxetine and Normal Controls Before and After Treatment With Estrogen[NCT00626340]Phase 418 participants (Actual)Interventional1999-07-31Completed
A Prospective Study of Pregnant and Postpartum Women With and Without Mood Disorders[NCT03615794]400 participants (Anticipated)Observational2017-10-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Comparison of Cortical GABA Levels in 4 Groups of Subjects Using Estrogen Alone, Fluoxetine Alone, Estrogen and Fluoxetine Combined in Pre and Post 4.0T Magnetic Resonance Spectroscopy Sessions.

"This study was conducted at Yale University almost two decades ago. Our group at the University of Pennsylvania only has very basic information about this study. This includes the number of participants, which was 18, and the fact that no adverse events occurred. Staff members at the University of Pennsylvania do not have access to any additional study data. The contact person who initially entered this study protocol information is no longer at the University of Pennsylvania and we are unable to contact for additional information.~We only know that 18 participants completed, but as far as we know data was never analyzed for these 18 participants." (NCT00626340)
Timeframe: Healthy controls will undergo scans pre and post 3 weeks of estrogen treatment. Women with depression will undergo scans pre and post 6 weeks of treatment with estrogen alone, estrogen and fluoxetine, or fluoxetine alone

Intervention ()
All Participants0

Trials

1 trial available for nortriptyline and Puerperal Disorders

ArticleYear
Prevention of recurrent postpartum major depression.
    Hospital & community psychiatry, 1994, Volume: 45, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder; Female; Humans; Nortriptyline; Odds Ratio; Pregnancy; Ps

1994
Prevention of recurrent postpartum major depression.
    Hospital & community psychiatry, 1994, Volume: 45, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder; Female; Humans; Nortriptyline; Odds Ratio; Pregnancy; Ps

1994
Prevention of recurrent postpartum major depression.
    Hospital & community psychiatry, 1994, Volume: 45, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder; Female; Humans; Nortriptyline; Odds Ratio; Pregnancy; Ps

1994
Prevention of recurrent postpartum major depression.
    Hospital & community psychiatry, 1994, Volume: 45, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder; Female; Humans; Nortriptyline; Odds Ratio; Pregnancy; Ps

1994

Other Studies

4 other studies available for nortriptyline and Puerperal Disorders

ArticleYear
NORTRIPTYLINE, AN ANTIDEPRESSANT.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Alcoholism; Antidepressive Agents; Depression; Depressive Disorder; Depressive Disorder, Major; Drug

1964
Amitriptyline and nortriptyline excretion in human breast milk.
    Psychopharmacology, 1982, Volume: 76, Issue:1

    Topics: Adult; Amitriptyline; Depressive Disorder; Female; Humans; Milk, Human; Nortriptyline; Pregnancy; Pu

1982
Serum nortriptyline levels in nursing mothers and their infants.
    The American journal of psychiatry, 1991, Volume: 148, Issue:9

    Topics: Breast Feeding; Depressive Disorder; Humans; Infant; Infant, Newborn; Nortriptyline; Puerperal Disor

1991
Milk concentrations of flupenthixol, nortriptyline and zuclopenthixol and between-breast differences in two patients.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:2

    Topics: Adult; Breast; Clopenthixol; Female; Flupenthixol; Humans; Hydrogen-Ion Concentration; Lactation; Mi

1988