Page last updated: 2024-11-01

nortriptyline and Osteoarthritis, Knee

nortriptyline has been researched along with Osteoarthritis, Knee in 2 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)

Research Excerpts

ExcerptRelevanceReference
" Adults with knee OA and a pain score of ≥20 points on the 50-point Western Ontario and McMaster University Osteoarthritis Index (WOMAC) pain subscale were randomised to receive either nortriptyline or identical placebo for 14 weeks."9.41Nortriptyline for pain in knee osteoarthritis: a double-blind randomised controlled trial in New Zealand general practice. ( Alchin, JS; Hooper, GJ; Hudson, B; Mangin, D; Stamp, LK; Thompson, BFL; Toop, L; Williman, JA, 2021)
" Adults with knee OA and a pain score of ≥20 points on the 50-point Western Ontario and McMaster University Osteoarthritis Index (WOMAC) pain subscale were randomised to receive either nortriptyline or identical placebo for 14 weeks."5.41Nortriptyline for pain in knee osteoarthritis: a double-blind randomised controlled trial in New Zealand general practice. ( Alchin, JS; Hooper, GJ; Hudson, B; Mangin, D; Stamp, LK; Thompson, BFL; Toop, L; Williman, JA, 2021)
"Nortriptyline is a readily-available, cheap and comparatively well-tolerated tricyclic antidepressant."2.80Nortriptyline in knee osteoarthritis (NortIKA Study): study protocol for a randomised controlled trial. ( Alchin, JS; Hooper, GJ; Hudson, B; Mangin, D; Stamp, LK; Thompson, BF; Toop, L; Williman, JA, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Hudson, B2
Williman, JA2
Stamp, LK2
Alchin, JS2
Hooper, GJ2
Mangin, D2
Thompson, BFL1
Toop, L2
Thompson, BF1

Trials

2 trials available for nortriptyline and Osteoarthritis, Knee

ArticleYear
Nortriptyline for pain in knee osteoarthritis: a double-blind randomised controlled trial in New Zealand general practice.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2021, Volume: 71, Issue:708

    Topics: Adult; Double-Blind Method; General Practice; Humans; New Zealand; Nortriptyline; Osteoarthritis, Kn

2021
Nortriptyline in knee osteoarthritis (NortIKA Study): study protocol for a randomised controlled trial.
    Trials, 2015, Oct-09, Volume: 16

    Topics: Analgesics; Arthralgia; Clinical Protocols; Double-Blind Method; Female; Humans; Male; Middle Aged;

2015