Page last updated: 2024-11-01

nortriptyline and Neoplasms

nortriptyline has been researched along with Neoplasms in 6 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)
"Nortriptyline promotes cell acidification and suppresses macropinocytosis, providing a link between fatty acid uptake and tumor progression."1.91Stopping the fat: Repurposing an antidepressant for cancer treatment. ( Bhullar, D; Commisso, C, 2023)
"Data collected included demographics, cancer and co-morbid diagnoses, and compliance to antidepressant medication using medication possession ratio (MPR) by patient, medication class, and individual agents."1.37Evaluation of medication compliance in patients on antidepressants at an outpatient tertiary cancer center setting. ( Adamus, A; Arbuckle, R; DaCosta Byfield, S; Feng, C; Hung, F; Lal, LS; Miller, LA; Zhuang, A, 2011)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Tukey, RH1
Strassburg, CP1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Chu, Q2
An, J2
Liu, P2
Song, Y2
Zhai, X2
Yang, R2
Niu, J2
Yang, C2
Li, B2
Bhullar, D1
Commisso, C1
Lal, LS1
Hung, F1
Feng, C1
Zhuang, A1
DaCosta Byfield, S1
Miller, LA1
Adamus, A1
Arbuckle, R1
Taube, AW1
Jenkins, C1
Bruera, E1

Reviews

2 reviews available for nortriptyline and Neoplasms

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015

Other Studies

4 other studies available for nortriptyline and Neoplasms

ArticleYear
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
    The Journal of experimental medicine, 2023, 03-06, Volume: 220, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Drug Repositioning; Fatty Acids; Fatty Liver; Liver; Meta

2023
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
    The Journal of experimental medicine, 2023, 03-06, Volume: 220, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Drug Repositioning; Fatty Acids; Fatty Liver; Liver; Meta

2023
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
    The Journal of experimental medicine, 2023, 03-06, Volume: 220, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Drug Repositioning; Fatty Acids; Fatty Liver; Liver; Meta

2023
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
    The Journal of experimental medicine, 2023, 03-06, Volume: 220, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Drug Repositioning; Fatty Acids; Fatty Liver; Liver; Meta

2023
Stopping the fat: Repurposing an antidepressant for cancer treatment.
    The Journal of experimental medicine, 2023, 03-06, Volume: 220, Issue:3

    Topics: Antidepressive Agents; Fatty Acids; Humans; Neoplasms; Nortriptyline

2023
Evaluation of medication compliance in patients on antidepressants at an outpatient tertiary cancer center setting.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Volume: 17, Issue:2

    Topics: Aged; Antidepressive Agents; Cancer Care Facilities; Depression; Electronic Health Records; Female;

2011
Is a "palliative" patient always a palliative patient? Two case studies.
    Journal of pain and symptom management, 1997, Volume: 13, Issue:6

    Topics: Acute Kidney Injury; Adaptation, Psychological; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-In

1997