nortriptyline has been researched along with Inflammation in 8 studies
Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The GABA amides of the antidepressants nortriptyline and fluoxetine, 1 and 2, were compared to their respective parent compounds in rodent models of pain." | 7.75 | Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity. ( Aharoni, A; Geffen, Y; Gil-Ad, I; Halbfinger, E; Nisemblat, Y; Nudelman, A; Rephaeli, A; Tarasenko, I; Tarasenko, N; Weizman, A, 2009) |
| " The authors tested the hypothesis that C-reactive protein (CRP), a commonly available marker of systemic inflammation, predicts differential response to escitalopram (a serotonin reuptake inhibitor) and nortriptyline (a norepinephrine reuptake inhibitor)." | 5.19 | An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline. ( Dernovsek, MZ; Dew, T; Farmer, A; Hauser, J; Henigsberg, N; Maier, W; McGuffin, P; Mors, O; Souery, D; Tansey, KE; Uher, R, 2014) |
| "The GABA amides of the antidepressants nortriptyline and fluoxetine, 1 and 2, were compared to their respective parent compounds in rodent models of pain." | 3.75 | Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity. ( Aharoni, A; Geffen, Y; Gil-Ad, I; Halbfinger, E; Nisemblat, Y; Nudelman, A; Rephaeli, A; Tarasenko, I; Tarasenko, N; Weizman, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Rephaeli, A | 1 |
| Gil-Ad, I | 1 |
| Aharoni, A | 1 |
| Tarasenko, I | 1 |
| Tarasenko, N | 1 |
| Geffen, Y | 1 |
| Halbfinger, E | 1 |
| Nisemblat, Y | 1 |
| Weizman, A | 1 |
| Nudelman, A | 1 |
| Bollenbach, M | 1 |
| Salvat, E | 1 |
| Daubeuf, F | 1 |
| Wagner, P | 1 |
| Yalcin, I | 1 |
| Humo, M | 1 |
| Letellier, B | 1 |
| Becker, LJ | 1 |
| Bihel, F | 1 |
| Bourguignon, JJ | 1 |
| Villa, P | 1 |
| Obrecht, A | 1 |
| Frossard, N | 1 |
| Barrot, M | 1 |
| Schmitt, M | 1 |
| Mu, W | 1 |
| Xu, G | 1 |
| Wang, Z | 1 |
| Li, Q | 1 |
| Sun, S | 1 |
| Qin, Q | 1 |
| Li, Z | 1 |
| Shi, W | 1 |
| Dai, W | 1 |
| Zhan, X | 1 |
| Wang, J | 1 |
| Bai, Z | 1 |
| Xiao, X | 1 |
| Zwicker, A | 1 |
| Fabbri, C | 1 |
| Rietschel, M | 1 |
| Hauser, J | 2 |
| Mors, O | 2 |
| Maier, W | 2 |
| Zobel, A | 1 |
| Farmer, A | 2 |
| Aitchison, KJ | 1 |
| McGuffin, P | 2 |
| Lewis, CM | 1 |
| Uher, R | 3 |
| Tansey, KE | 1 |
| Dew, T | 1 |
| Dernovsek, MZ | 1 |
| Henigsberg, N | 1 |
| Souery, D | 1 |
| Kunte, H | 1 |
| Rentzsch, J | 1 |
| Kronenberg, G | 1 |
| Kragh-Sørensen, P | 1 |
| Larsen, NE | 1 |
1 review available for nortriptyline and Inflammation
| Article | Year |
|---|---|
Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Guanidines; Humans; Inflammatio | 2018 |
2 trials available for nortriptyline and Inflammation
| Article | Year |
|---|---|
Genetic disposition to inflammation and response to antidepressants in major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; C-Reactive Protein; Citalopram; Depressive Disorder, Major; Fem | 2018 |
An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline.
Topics: Academic Medical Centers; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tr | 2014 |
5 other studies available for nortriptyline and Inflammation
| Article | Year |
|---|---|
Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity.
Topics: Analgesics; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Fluoxetine; Formaldehyde; gam | 2009 |
Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation.
Topics: Animals; Antidepressive Agents, Tricyclic; Chemical and Drug Induced Liver Injury; Furans; Inflammas | 2023 |
Response to Kunte et al.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; C-Reactive Protein; Cita | 2015 |
A new role for nortriptyline in depression associated with vascular disease?
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; C-Reactive Protein; Cita | 2015 |
Factors influencing nortriptyline steady-state kinetics: plasma and saliva levels.
Topics: Adult; Age Factors; Aged; Dose-Response Relationship, Drug; Female; Humans; Inflammation; Kinetics; | 1980 |