nortriptyline has been researched along with Hypotension in 9 studies
Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The investigators studied a patient with a nortriptyline HCI level of 1,205 ng/mL who had four generalized grand mal seizures, each lasting between 60 and 90 seconds that were immediately followed by hypotension requiring norepinephrine support." | 7.69 | Recurrent hypotension immediately after seizures in nortriptyline overdose. ( Bell, A; Gaynor, B; Lipper, B, 1994) |
| " The investigators studied a patient with a nortriptyline HCI level of 1,205 ng/mL who had four generalized grand mal seizures, each lasting between 60 and 90 seconds that were immediately followed by hypotension requiring norepinephrine support." | 3.69 | Recurrent hypotension immediately after seizures in nortriptyline overdose. ( Bell, A; Gaynor, B; Lipper, B, 1994) |
| " Using the weight-adjusted dosage schedule, 18 of the 21 patients attained plasma concentrations of nortriptyline within the presumed therapeutic range; however, no clear relationship could be established between plasma concentrations and clinical response." | 1.28 | Simulated home treatment of depression with nortriptyline. ( Hollister, L; Peabody, C; Van Norman, J; Warner, D, 1991) |
| "Phenytoin has been proposed as a prophylaxis and treatment of these dysrhythmias, since it is thought to improve conduction in this setting." | 1.27 | Phenytoin prophylaxis of cardiotoxicity in experimental amitriptyline poisoning. ( Callaham, M; Pentel, P; Schumaker, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gold, MS | 1 |
| Pottash, AC | 1 |
| Lipper, B | 2 |
| Gaynor, BD | 1 |
| Bell, A | 1 |
| Gaynor, B | 1 |
| Peabody, C | 1 |
| Van Norman, J | 1 |
| Hollister, L | 1 |
| Warner, D | 1 |
| Severinsen, IK | 1 |
| Nielsen, HK | 1 |
| Zácková, P | 1 |
| Kunová, A | 1 |
| Benetková, M | 1 |
| Callaham, M | 1 |
| Schumaker, H | 1 |
| Pentel, P | 1 |
| Rendoing, J | 1 |
| Choisy, H | 1 |
| Pascalis, G | 1 |
| Bajolet, A | 1 |
| Gisselmann, A | 1 |
| Schuckit, M | 1 |
| Robins, E | 1 |
| Feighner, J | 1 |
9 other studies available for nortriptyline and Hypotension
| Article | Year |
|---|---|
Depression: diagnosis and treatment with tricyclic antidepressants.
Topics: Age Factors; Antidepressive Agents, Tricyclic; Black People; Chromatography, High Pressure Liquid; D | 1981 |
Value of serum tricyclic antidepressant levels with massive nortriptyline overdose and persistent hypotension.
Topics: Drug Overdose; Female; Humans; Hypotension; Nortriptyline; Prognosis; Respiratory Distress Syndrome | 1995 |
Recurrent hypotension immediately after seizures in nortriptyline overdose.
Topics: Biological Availability; Blood Pressure; Drug Overdose; Female; Heart; Humans; Hypotension; Midazola | 1994 |
Simulated home treatment of depression with nortriptyline.
Topics: Adult; Blood Pressure; Depressive Disorder; Female; Home Care Services; Humans; Hypotension; Male; M | 1991 |
[Nortriptyline poisoning with severe, treatable hypotension].
Topics: Adult; Diagnosis, Differential; Humans; Hypotension; Male; Norepinephrine; Nortriptyline; Suicide, A | 1991 |
Different cardiovascular effects of tricyclic antidepressants in the conscious and anesthetized rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cardiovascular System; Dose-Response Relat | 1989 |
Phenytoin prophylaxis of cardiotoxicity in experimental amitriptyline poisoning.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Dogs; Electrocardiography; Heart; Hypotens | 1988 |
[Acute poisoning with nortriptyline].
Topics: Adult; Apnea; Bundle-Branch Block; Cardiac Complexes, Premature; Coma; Diuresis; Electrocardiography | 1969 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug | 1971 |