Page last updated: 2024-11-01

nortriptyline and Dysesthesia

nortriptyline has been researched along with Dysesthesia in 5 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Research Excerpts

ExcerptRelevanceReference
"A controlled clinical trial on the efficacy of a nortriptyline-fluphenazine combination was carried out in patients with painful diabetic polyneuropathy."5.05Nortriptyline and fluphenazine in the symptomatic treatment of diabetic neuropathy. A double-blind cross-over study. ( Dies, H; Gomez-Perez, FJ; Gonzalez-Barranco, J; Lozano-Castañeda, O; Rodriguez-Rivera, GJ; Rull, JA, 1985)
" Subjects suffering from traumatic dysesthesia of the trigeminal nerve were treated with capsaicin, a substance P depleter with significant long-term effects."3.69Traumatic dysesthesia of the trigeminal nerve. ( Canavan, D; Graff-Radford, SB; Gratt, BM, 1994)
"Despite many therapeutic options, painful diabetic neuropathy is still a common and challenging complication of diabetes mellitus and is often resistant to treatment with current modalities."2.74Vitamin B12 may be more effective than nortriptyline in improving painful diabetic neuropathy. ( Chehrei, A; Majidi, H; Siavash, M; Talaei, A, 2009)
"No significant differences in paresthesia were observed in the first treatment period between nortriptyline and placebo (means of 49 and 55 respectively on a 0-100 point scale, P=0."2.70Phase III evaluation of nortriptyline for alleviation of symptoms of cis-platinum-induced peripheral neuropathy. ( Hammack, JE; Johnson, JA; Loprinzi, CL; Michalak, JC; Novotny, PJ; Rowland, KM; Sloan, JA; Soori, GS; Stella, PJ; Tirona, MT, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Talaei, A1
Siavash, M1
Majidi, H1
Chehrei, A1
Canavan, D1
Graff-Radford, SB1
Gratt, BM1
Gómez-Pérez, FJ2
Choza, R1
Ríos, JM1
Reza, A1
Huerta, E1
Aguilar, CA1
Rull, JA2
Hammack, JE1
Michalak, JC1
Loprinzi, CL1
Sloan, JA1
Novotny, PJ1
Soori, GS1
Tirona, MT1
Rowland, KM1
Stella, PJ1
Johnson, JA1
Dies, H1
Rodriguez-Rivera, GJ1
Gonzalez-Barranco, J1
Lozano-Castañeda, O1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Kinetics of Endocannabinoids in Patients With Chemotherapy Induced Peripheral Neuropathy by Using a Portable Metered-Dose Cannabis Inhaler[NCT04376437]40 participants (Anticipated)Interventional2022-03-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for nortriptyline and Dysesthesia

ArticleYear
Vitamin B12 may be more effective than nortriptyline in improving painful diabetic neuropathy.
    International journal of food sciences and nutrition, 2009, Volume: 60 Suppl 5

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tricyclic; Bloo

2009
Nortriptyline-fluphenazine vs. carbamazepine in the symptomatic treatment of diabetic neuropathy.
    Archives of medical research, 1996,Winter, Volume: 27, Issue:4

    Topics: Adult; Analgesics, Non-Narcotic; Antidepressive Agents, Tricyclic; Carbamazepine; Cross-Over Studies

1996
Phase III evaluation of nortriptyline for alleviation of symptoms of cis-platinum-induced peripheral neuropathy.
    Pain, 2002, Volume: 98, Issue:1-2

    Topics: Antidepressive Agents, Tricyclic; Cisplatin; Cross-Over Studies; Dose-Response Relationship, Drug; D

2002
Nortriptyline and fluphenazine in the symptomatic treatment of diabetic neuropathy. A double-blind cross-over study.
    Pain, 1985, Volume: 23, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Diabetic Neuropathies; Double-Blind Method; Female; Fluphenaz

1985

Other Studies

1 other study available for nortriptyline and Dysesthesia

ArticleYear
Traumatic dysesthesia of the trigeminal nerve.
    Journal of orofacial pain, 1994,Fall, Volume: 8, Issue:4

    Topics: Administration, Topical; Aged; Antidepressive Agents, Tricyclic; Capsaicin; Desipramine; Drug Therap

1994