nortriptyline has been researched along with Depressive Disorder, Treatment-Resistant in 4 studies
Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
Depressive Disorder, Treatment-Resistant: Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.)
Excerpt | Relevance | Reference |
---|---|---|
" By study phase, Eight of 27 (30%) patients remitted with initial dosing of tranylcypromine up to 60 mg/d, 6/18 (33%) remitted with above PDR dosing of tranylcypromine up to 120 mg/d, and 1/6 (17%) to adding dextroamphetamine." | 2.79 | How treatable is refractory depression? ( Deliyannides, DA; McGrath, PJ; Stewart, JW, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Ebell, MH | 1 |
Cristancho, P | 1 |
Lenard, E | 1 |
Lenze, EJ | 1 |
Miller, JP | 1 |
Brown, PJ | 1 |
Roose, SP | 1 |
Montes-Garcia, C | 1 |
Blumberger, DM | 1 |
Mulsant, BH | 1 |
Lavretsky, H | 1 |
Rollman, BL | 1 |
Reynolds, CF | 1 |
Karp, JF | 1 |
Stewart, JW | 1 |
Deliyannides, DA | 1 |
McGrath, PJ | 1 |
Fawcett, J | 1 |
Rush, AJ | 1 |
Vukelich, J | 1 |
Diaz, SH | 1 |
Dunklee, L | 1 |
Romo, P | 1 |
Yarns, BC | 1 |
Escalona, R | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Pilot Study of Treatment for Refractory Depression With Sequential Trials of Tranylcypromine, Tranylcypromine Plus Dextroamphetamine, Tranylcypromine Plus Triiodothyronine.[NCT00296686] | Phase 4 | 31 participants (Actual) | Interventional | 2001-09-30 | Terminated (stopped due to Study is no longer funded.) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 trials available for nortriptyline and Depressive Disorder, Treatment-Resistant
Article | Year |
---|---|
Optimizing Outcomes of Treatment-Resistant Depression in Older Adults (OPTIMUM): Study Design and Treatment Characteristics of the First 396 Participants Randomized.
Topics: Aged; Antidepressive Agents; Aripiprazole; Bupropion; Depressive Disorder, Treatment-Resistant; Huma | 2019 |
How treatable is refractory depression?
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Depressive Disorder, Major; Depress | 2014 |
2 other studies available for nortriptyline and Depressive Disorder, Treatment-Resistant
Article | Year |
---|---|
Augmentation With Aripiprazole or Bupropion, or a Switch to Nortriptyline, Effective for Treatment-Resistant Depression in Older Adults.
Topics: Aged; Aripiprazole; Bupropion; Depression; Depressive Disorder, Treatment-Resistant; Humans; Nortrip | 2023 |
Clinical Experience With High-Dosage Pramipexole in Patients With Treatment-Resistant Depressive Episodes in Unipolar and Bipolar Depression.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Benzothiazoles; Bipolar Disorder; Bupropion; | 2016 |