nortriptyline has been researched along with Chronic Kidney Failure in 5 studies
Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For trimipramine the AUC was significantly higher in patients." | 2.67 | [Comparative study of the pharmacokinetics of amitriptyline oxide and trimipramine after single administration in healthy male probands and patients with renal failure]. ( Degen, J; Fischer, W; Höxter, G; Pintar, P; Seiberling, M; Steinhauer, HB; Wölke, E, 1993) |
| "Nortriptyline kinetics were unaltered, but the elimination of the metabolites was reduced in both groups of patients." | 1.26 | Nortriptyline metabolism in chronic renal failure: metabolite elimination. ( Braithwaite, R; Dawling, S; Lynn, K; Rosser, R, 1982) |
| " 2 The median nortriptyline half-life was 25." | 1.26 | The pharmacokinetics of nortriptyline in patients with chronic renal failure. ( Braithwaite, R; Dawlilng, S; Lynn, K; Rosser, R, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dawling, S | 1 |
| Lynn, K | 2 |
| Rosser, R | 3 |
| Braithwaite, R | 2 |
| Dawlilng, S | 1 |
| Degen, J | 1 |
| Wölke, E | 1 |
| Seiberling, M | 1 |
| Pintar, P | 1 |
| Höxter, G | 1 |
| Steinhauer, HB | 1 |
| Fischer, W | 1 |
| Lieberman, JA | 1 |
| Cooper, TB | 1 |
| Suckow, RF | 1 |
| Steinberg, H | 1 |
| Borenstein, M | 1 |
| Brenner, R | 1 |
| Kane, JM | 1 |
1 trial available for nortriptyline and Chronic Kidney Failure
| Article | Year |
|---|---|
[Comparative study of the pharmacokinetics of amitriptyline oxide and trimipramine after single administration in healthy male probands and patients with renal failure].
Topics: Adult; Aged; Amitriptyline; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle | 1993 |
4 other studies available for nortriptyline and Chronic Kidney Failure
| Article | Year |
|---|---|
Nortriptyline metabolism in chronic renal failure: metabolite elimination.
Topics: Adolescent; Adult; Aged; Chromatography, Gas; Depressive Disorder; Female; Humans; Kidney Failure, C | 1982 |
The pharmacokinetics of nortriptyline in patients with chronic renal failure.
Topics: Adolescent; Adult; Aged; Female; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle | 1981 |
Depression during renal dialysis and following transplantation.
Topics: Amitriptyline; Depression; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Mi | 1976 |
Tricyclic antidepressant and metabolite levels in chronic renal failure.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chromatography, Liquid; Depression; Desipramine; | 1985 |