Page last updated: 2024-11-01

nortriptyline and Chronic Insomnia

nortriptyline has been researched along with Chronic Insomnia in 10 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Research Excerpts

ExcerptRelevanceReference
"Ninety-two middle-aged and elderly patients with disabling tinnitus participated in a double-blind randomized clinical trial comparing nortriptyline (a tricyclic antidepressant) to placebo."5.07Antidepressant treatment of tinnitus patients: report of a randomized clinical trial and clinical prediction of benefit. ( Dobie, RA; Katon, WJ; Russo, J; Sakai, CS; Sullivan, MD, 1993)
"In patients with migraine, prophylaxis with atorvastatin significantly improved the frequency of headache and QOL over 24 weeks compared with placebo with no effect on the intensity of headache."3.11The preventive effect of the combination of atorvastatin and nortriptyline in migraine-type headache: a randomized, triple-blind, placebo-controlled trial. ( Mohammadi, F; Rahmany, R; Saghafi, F; Sahebnasagh, A; Sherafat, A, 2022)
" 4 Compared with diazepam the tested drug has a longer plasma apparent half-life and a lower relative clearance."2.64Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline. ( Alberti, GG; De Maio, D; Franciosi, P; Gomeni, R; Scieghi, G; Tognoni, G, 1975)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Sherafat, A1
Sahebnasagh, A1
Rahmany, R1
Mohammadi, F1
Saghafi, F1
Keers, R1
Bonvicini, C1
Scassellati, C1
Uher, R1
Placentino, A1
Giovannini, C1
Rietschel, M1
Henigsberg, N1
Kozel, D1
Mors, O1
Maier, W1
Hauser, J1
Souery, D1
Mendlewicz, J1
Schmäl, C1
Zobel, A1
Larsen, ER1
Szczepankiewicz, A1
Kovacic, Z1
Elkin, A1
Craig, I1
McGuffin, P1
Farmer, AE1
Aitchison, KJ1
Gennarelli, M1
Rosenlicht, NZ1
Riley-Lazo, KP1
Pöldinger, W1
Streichenwein, SM1
Hoc, J1
Dobie, RA1
Sakai, CS1
Sullivan, MD1
Katon, WJ1
Russo, J1
Tognoni, G1
Gomeni, R1
De Maio, D1
Alberti, GG1
Franciosi, P1
Scieghi, G1
Stewart, JA1
Mitchell, PH1
Kessell, A1
Pearce, TA1
Holt, NF1
Kagan, G1

Trials

8 trials available for nortriptyline and Chronic Insomnia

ArticleYear
The preventive effect of the combination of atorvastatin and nortriptyline in migraine-type headache: a randomized, triple-blind, placebo-controlled trial.
    Neurological research, 2022, Volume: 44, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Atorvastatin; Constipation; Double-Blind Method; Drug Therapy,

2022
Variation in GNB3 predicts response and adverse reactions to antidepressants.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:7

    Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Europe; Female; Gene Frequency

2011
A clinical trial comparing nomifensine and nortriptyline.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 1

    Topics: Adolescent; Adult; Age Factors; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method;

1982
The clinical efficacy and side-effects of mianserin and nortriptyline in depressed out-patients: a double-blind randomized trial.
    Current medical research and opinion, 1982, Volume: 8, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Clinical Trials as Topic; Depression; Depressive Disorder; Dibenzazepi

1982
Antidepressant treatment of tinnitus patients: report of a randomized clinical trial and clinical prediction of benefit.
    The American journal of otology, 1993, Volume: 14, Issue:1

    Topics: Aged; Depressive Disorder; Disabled Persons; Female; Humans; Loudness Perception; Male; Middle Aged;

1993
Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Diazepam; Drug Evaluation; Drug Therapy, Combination; Half-Li

1975
A comparative trial of desipramine and nortriptyline in depression.
    The British journal of psychiatry : the journal of mental science, 1968, Volume: 114, Issue:509

    Topics: Adolescent; Adult; Aged; Anxiety; Clinical Trials as Topic; Depression; Desipramine; Electroconvulsi

1968
A controlled study of nortriptyline and imipramine.
    The American journal of psychiatry, 1970, Volume: 126, Issue:7

    Topics: Anxiety; Body Weight; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Nortriptylin

1970

Other Studies

2 other studies available for nortriptyline and Chronic Insomnia

ArticleYear
Interactions of cyclobenzaprine and tricyclic antidepressants.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Interactions; Humans; Mal

2005
A pilot trial of nortryptiline in the treatment of mentally disturbed patients in general practice.
    The Practitioner, 1965, Volume: 195, Issue:169

    Topics: Adolescent; Adult; Antidepressive Agents; Anxiety; Child; Depression; Family Practice; Female; Human

1965