nortriptyline has been researched along with Cardiac Diseases in 10 studies
Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 to 7 mg base per kilogram caused significantly more arrhythmias than did E-10-hydroxynortriptyline (E-10-OH-NT) but was not significantly different from Z-10-hydroxynortriptyline (Z-10-OH-NT) in this effect." | 3.68 | Comparative cardiotoxicity of nortriptyline and its isomeric 10-hydroxymetabolites. ( Everett, G; Perel, JM; Pollock, BG, 1992) |
| "Nortriptyline hydrochloride is an effective antidepressant that, in depressed patients without heart disease, causes significantly less orthostatic hypotension than imipramine." | 1.27 | Nortriptyline in depressed patients with left ventricular impairment. ( Bigger, JT; Giardina, EG; Glassman, AH; Johnson, LL; Roose, SP; Walsh, BT; Woodring, S, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CHESROW, EJ | 1 |
| KAPLITZ, SE | 1 |
| BREME, JT | 1 |
| SABATINI, R | 1 |
| VETRA, H | 1 |
| MARQUARDT, GH | 1 |
| Gold, MS | 1 |
| Pottash, AC | 1 |
| Roose, SP | 4 |
| Glassman, AH | 3 |
| Attia, E | 2 |
| Woodring, S | 3 |
| Miller, MD | 1 |
| Curtiss, EI | 1 |
| Marino, L | 1 |
| Houck, PR | 1 |
| Paradis, CF | 1 |
| Mazumdar, S | 1 |
| Pollock, BG | 2 |
| Foglia, J | 1 |
| Reynolds, CF | 1 |
| Giardina, EG | 2 |
| Bigger, JT | 2 |
| Spatz, E | 1 |
| Bonaccorsi, A | 1 |
| Garattini, S | 1 |
| Everett, G | 1 |
| Perel, JM | 1 |
| Johnson, LL | 1 |
| Walsh, BT | 1 |
| Luke, CM | 1 |
2 reviews available for nortriptyline and Cardiac Diseases
| Article | Year |
|---|---|
Treatment of depression in patients with heart disease.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Comorbidity; | 1999 |
Cardiac effects of nortriptyline and other tricyclic antidepressant drugs.
Topics: Aged; Aging; Animals; Antidepressive Agents, Tricyclic; Electrocardiography; Heart; Heart Diseases; | 1978 |
2 trials available for nortriptyline and Cardiac Diseases
| Article | Year |
|---|---|
Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia.
Topics: Age Factors; Aged; Comorbidity; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Female | 1994 |
Long-term ECG changes in depressed elderly patients treated with nortriptyline. A double-blind, randomized, placebo-controlled evaluation.
Topics: Age Factors; Aged; Analysis of Variance; Antidepressive Agents, Tricyclic; Depressive Disorder; Doub | 1998 |
6 other studies available for nortriptyline and Cardiac Diseases
| Article | Year |
|---|---|
NORTRIPTYLINE FOR THE TREATMENT OF ANXIETY AND DEPRESSION IN CHRONICALLY ILL AND GERIATRIC PATIENTS.
Topics: Aged; Alcoholism; Antidepressive Agents; Anxiety; Cerebrovascular Disorders; Chronic Disease; Depres | 1964 |
Depression: diagnosis and treatment with tricyclic antidepressants.
Topics: Age Factors; Antidepressive Agents, Tricyclic; Black People; Chromatography, High Pressure Liquid; D | 1981 |
Cardiovascular effects of fluoxetine in depressed patients with heart disease.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Blood Pressure; Comorbidity; Depressive Disorder; Dru | 1998 |
Comparative cardiotoxicity of nortriptyline and its isomeric 10-hydroxymetabolites.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Blood Proteins; Cardiac Output, Low; Chromatography, | 1992 |
Nortriptyline in depressed patients with left ventricular impairment.
Topics: Aged; Aged, 80 and over; Blood Pressure; Depressive Disorder; Female; Heart Diseases; Humans; Male; | 1986 |
Tricyclic antidepressants and heart disease.
Topics: Amitriptyline; Antidepressive Agents; Heart Diseases; Humans; Nortriptyline | 1971 |