nortriptyline has been researched along with Body Weight in 25 studies
Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To compare changes in body weight during treatment with different antidepressants, body weight and height were measured at baseline and after 6, 8, 12 and 26 wk treatment with escitalopram or nortriptyline in 630 adults with moderate-to-severe unipolar depression participating in GENDEP, a part-randomized open-label study." | 5.15 | Changes in body weight during pharmacological treatment of depression. ( Aitchison, KJ; Dernovsek, MZ; Farmer, A; Gray, JM; Hauser, J; Henigsberg, N; Kalember, P; Keers, R; Kozel, D; Larsen, ER; Maier, W; McGuffin, P; Mendlewicz, J; Mors, O; Placentino, A; Rietschel, M; Souery, D; Strohmaier, J; Szczepankiewicz, A; Uher, R; Zobel, A, 2011) |
| "Higher BMI and obesity predicted poor response to nortriptyline but did not significantly influence response to escitalopram." | 5.14 | Body weight as a predictor of antidepressant efficacy in the GENDEP project. ( Aitchison, KJ; Dernovsek, MZ; Farmer, A; Gunasinghe, C; Hauser, J; Henigsberg, N; Kalember, P; Kozel, D; Larsen, ER; Leszczynska-Rodziewicz, A; Linotte, S; Maier, W; McGuffin, P; Mors, O; Pedrini, L; Perroud, N; Placentino, A; Rietschel, M; Souery, D; Strohmaier, J; Uher, R; Zobel, A, 2009) |
| "Twenty-two female patients with anorexia nervosa, restricted type, 14-35 years old, were treated with a 4-month course of combined cognitive-behavioral therapy, nutritional counselling and antidepressant drugs (nortriptyline for 7, fluoxetine for 15)." | 5.08 | Combined cognitive-behavioral, psychopharmacological and nutritional therapy in eating disorders. 1. Anorexia nervosa--restricted type. ( Brambilla, F; Brunetta, M; Draisci, A; Peirone, A, 1995) |
| "Therapeutic drug monitoring data for nortriptyline (674 analyses from 578 patients) were evaluated with the nonparametric maximum likelihood (NPML) method in order to determine the population kinetic parameters of this drug and their relation to age, body weight and duration of treatment." | 3.69 | Population pharmacokinetics of nortriptyline during monotherapy and during concomitant treatment with drugs that inhibit CYP2D6--an evaluation with the nonparametric maximum likelihood method. ( Jerling, M; Mallet, A; Mentré, F; Merlé, Y, 1994) |
| "The authors investigated ECG measurements in 21 children with major depressive disorder treated with nortriptyline at plasma levels of 50-100 ng/ml." | 3.67 | Serial ECG measurements at controlled plasma levels of nortriptyline in depressed children. ( Abel, AS; Chestnut, EC; Cooper, TB; Farooki, ZQ; Geller, B, 1985) |
| "Nortriptyline treatment was initiated with a 75- to 125-mg dose depending on weight in 26 depressed inpatients in an open-label study." | 2.67 | High initial nortriptyline doses in the treatment of depression. ( Griffin, M; Peabody, CA; Warner, MD, 1993) |
| "Rehabilitation of COPD-patients is an important part of the therapeutic management." | 1.33 | [COPD-rehabilitation]. ( Lichtenschopf, A; Zwick, H, 2005) |
| "Paroxetine and drug-free treatment did not affect any of these parameters." | 1.31 | Effects of antidepressants on weight and on the plasma levels of leptin, TNF-alpha and soluble TNF receptors: A longitudinal study in patients treated with amitriptyline or paroxetine. ( Haack, M; Hinze-Selch, D; Kraus, T; Kühn, M; Pollmächer, T; Schuld, A; Uhr, M, 2000) |
| "The postulated therapeutic activity of nortriptyline metabolites has prompted investigation of dosage adjustments based on plasma levels of nortriptyline (NT) and its metabolites." | 1.28 | Relationships among nortriptyline, 10-OH(E)nortriptyline, and 10-OH(Z)nortriptyline steady-state plasma levels and nortriptyline dosage. ( Hurst, HE; Jones, DR; Lukey, BJ; Wright, JH, 1989) |
| " These findings show that chronic administration of low-modest doses of tricyclic antidepressants frequently cause considerable weight gain and can significantly interfere with the ability to provide long-term maintenance therapy." | 1.27 | Weight gain. A side-effect of tricyclic antidepressants. ( Berken, GH; Stern, WC; Weinstein, DO, 1984) |
| "In imipramine-treated patients this finding was associated with a decreased rate of drug elimination from plasma." | 1.26 | Relationship between age and tricyclic antidepressant plasma levels. ( Cooper, TB; Friedman, MJ; Green, R; Ives, JO; Nies, A; Ravaris, CL; Robinson, DS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (44.00) | 18.7374 |
| 1990's | 7 (28.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Puzhko, S | 1 |
| Aboushawareb, SAE | 1 |
| Kudrina, I | 1 |
| Schuster, T | 1 |
| Barnett, TA | 1 |
| Renoux, C | 1 |
| Bartlett, G | 1 |
| Uher, R | 2 |
| Mors, O | 2 |
| Hauser, J | 2 |
| Rietschel, M | 2 |
| Maier, W | 2 |
| Kozel, D | 2 |
| Henigsberg, N | 2 |
| Souery, D | 2 |
| Placentino, A | 2 |
| Perroud, N | 1 |
| Dernovsek, MZ | 2 |
| Strohmaier, J | 2 |
| Larsen, ER | 2 |
| Zobel, A | 2 |
| Leszczynska-Rodziewicz, A | 1 |
| Kalember, P | 2 |
| Pedrini, L | 1 |
| Linotte, S | 1 |
| Gunasinghe, C | 1 |
| Aitchison, KJ | 2 |
| McGuffin, P | 2 |
| Farmer, A | 2 |
| Keers, R | 1 |
| Gray, JM | 1 |
| Szczepankiewicz, A | 1 |
| Mendlewicz, J | 1 |
| Zwick, H | 1 |
| Lichtenschopf, A | 1 |
| Berken, GH | 1 |
| Weinstein, DO | 1 |
| Stern, WC | 1 |
| Zetin, M | 1 |
| Frost, NR | 1 |
| Brumfield, D | 1 |
| Stone, RA | 1 |
| Brambilla, F | 1 |
| Draisci, A | 1 |
| Peirone, A | 1 |
| Brunetta, M | 1 |
| Jerling, M | 1 |
| Merlé, Y | 1 |
| Mentré, F | 1 |
| Mallet, A | 1 |
| Warner, MD | 1 |
| Griffin, M | 1 |
| Peabody, CA | 1 |
| Marraccini, RL | 1 |
| Reynolds, CF | 2 |
| Houck, PR | 1 |
| Miller, MD | 2 |
| Frank, E | 1 |
| Perel, JM | 2 |
| Cornes, C | 1 |
| Mazumdar, S | 3 |
| Kupfer, DJ | 2 |
| Hinze-Selch, D | 1 |
| Schuld, A | 1 |
| Kraus, T | 1 |
| Kühn, M | 1 |
| Uhr, M | 1 |
| Haack, M | 1 |
| Pollmächer, T | 1 |
| Weber, E | 1 |
| Stack, J | 1 |
| Pollock, BG | 2 |
| Mulsant, B | 1 |
| Begley, A | 1 |
| Gendall, KA | 1 |
| Joyce, PR | 1 |
| Mulder, RT | 1 |
| Sullivan, PF | 1 |
| Coble, PA | 1 |
| Rubinstein, D | 1 |
| Lauer, JW | 1 |
| Nies, A | 1 |
| Robinson, DS | 1 |
| Friedman, MJ | 1 |
| Green, R | 1 |
| Cooper, TB | 3 |
| Ravaris, CL | 1 |
| Ives, JO | 1 |
| Simpson, GM | 1 |
| Lee, JH | 1 |
| Paradis, CF | 1 |
| Stack, JA | 1 |
| George, CJ | 1 |
| Rifai, AH | 1 |
| Yutrzenka, GJ | 1 |
| Patrick, GA | 1 |
| Rosenberger, W | 1 |
| Corona, GL | 1 |
| Cucchi, ML | 1 |
| Frattini, P | 1 |
| Santagostino, G | 1 |
| Schinelli, S | 1 |
| Zerbi, F | 1 |
| Savoldi, F | 1 |
| Lukey, BJ | 1 |
| Jones, DR | 1 |
| Wright, JH | 1 |
| Hurst, HE | 1 |
| Geller, B | 1 |
| Farooki, ZQ | 1 |
| Chestnut, EC | 1 |
| Abel, AS | 1 |
| Schumacher, GE | 1 |
| Weiner, J | 1 |
| Kessell, A | 1 |
| Pearce, TA | 1 |
| Holt, NF | 1 |
| Asberg, M | 1 |
| Evans, DA | 1 |
| Sjöqvist, F | 1 |
1 review available for nortriptyline and Body Weight
| Article | Year |
|---|---|
Excess body weight as a predictor of response to treatment with antidepressants in patients with depressive disorder.
Topics: Adult; Antidepressive Agents; Body Weight; Citalopram; Depressive Disorder; Humans; Nortriptyline | 2020 |
11 trials available for nortriptyline and Body Weight
| Article | Year |
|---|---|
Body weight as a predictor of antidepressant efficacy in the GENDEP project.
Topics: Adult; Affect; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Appetite; | 2009 |
Changes in body weight during pharmacological treatment of depression.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Body Mass Index; Body Weight; Citalopram; Depressive | 2011 |
Amitriptyline stimulates weight gain in hemodialysis patients.
Topics: Adult; Aged; Amitriptyline; Anorexia Nervosa; Blood Pressure; Body Weight; Clinical Trials as Topic; | 1982 |
Combined cognitive-behavioral, psychopharmacological and nutritional therapy in eating disorders. 1. Anorexia nervosa--restricted type.
Topics: Adolescent; Adult; Anorexia Nervosa; Antidepressive Agents, Second-Generation; Antidepressive Agents | 1995 |
High initial nortriptyline doses in the treatment of depression.
Topics: Adult; Body Weight; Depressive Disorder; Drug Administration Schedule; Female; Hospitalization; Huma | 1993 |
A double-blind, placebo-controlled assessment of nortriptyline's side-effects during 3-year maintenance treatment in elderly patients with recurrent major depression.
Topics: Aged; Analysis of Variance; Antidepressive Agents, Tricyclic; Body Mass Index; Body Weight; Constipa | 1999 |
Weight change in older depressed patients during acute pharmacotherapy with paroxetine and nortriptyline: a double-blind randomized trial.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Body Weight; Depressive Disorder, Major; | 2000 |
The effects of fluoxetine versus nortriptyline on body weight in depression.
Topics: Adrenergic Uptake Inhibitors; Body Weight; Female; Fluoxetine; Humans; Male; Mood Disorders; Nortrip | 2000 |
Changes in weight during treatment for depression.
Topics: Adult; Amitriptyline; Appetite; Body Weight; Depression; Female; Humans; Nortriptyline; Placebos | 1979 |
The effect of tricyclic antidepressant compounds on patients with passive-dependent personality traits.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clinical Trials as Topic; Dependency, Psycholo | 1976 |
A controlled study of nortriptyline and imipramine.
Topics: Anxiety; Body Weight; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Nortriptylin | 1970 |
13 other studies available for nortriptyline and Body Weight
| Article | Year |
|---|---|
[COPD-rehabilitation].
Topics: Acupuncture Therapy; Adrenergic alpha-Agonists; Antidepressive Agents, Second-Generation; Antidepres | 2005 |
Weight gain. A side-effect of tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Appetite; Body Weight; Depressive Disorder; | 1984 |
Population pharmacokinetics of nortriptyline during monotherapy and during concomitant treatment with drugs that inhibit CYP2D6--an evaluation with the nonparametric maximum likelihood method.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Body Weight; Chromatography, High Press | 1994 |
Effects of antidepressants on weight and on the plasma levels of leptin, TNF-alpha and soluble TNF receptors: A longitudinal study in patients treated with amitriptyline or paroxetine.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidep | 2000 |
Relationship between age and tricyclic antidepressant plasma levels.
Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bod | 1977 |
Thymoleptic and neuroleptic drug plasma levels in psychiatry: current status.
Topics: Antidepressive Agents, Tricyclic; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; | 1976 |
Nortriptyline and weight change in depressed patients over 60.
Topics: Aged; Aging; Body Weight; Depressive Disorder; Humans; Nortriptyline; Psychiatric Status Rating Scal | 1992 |
Substitution of psychoactive drugs in pentobarbital-dependent rats.
Topics: Animals; Antidepressive Agents; Arousal; Body Weight; Brain; Bromazepam; Bupropion; Diazepam; Dose-R | 1990 |
Aspects of amitriptyline and nortriptyline plasma levels monitoring in depression.
Topics: Adult; Aged; Aging; Amitriptyline; Body Weight; Depressive Disorder; Female; Humans; Middle Aged; Mo | 1990 |
Relationships among nortriptyline, 10-OH(E)nortriptyline, and 10-OH(Z)nortriptyline steady-state plasma levels and nortriptyline dosage.
Topics: Body Weight; Humans; Nortriptyline; Obesity | 1989 |
Serial ECG measurements at controlled plasma levels of nortriptyline in depressed children.
Topics: Age Factors; Body Weight; Child; Child, Preschool; Depressive Disorder; Electrocardiography; Female; | 1985 |
Practical pharmacokinetic techniques for drug consultation and evaluation. 3. Psychotherapeutic drugs as prototypes for illustrating some considerations in pharmacist-generated dosage regimens.
Topics: Body Weight; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation; Half-Life; | 1974 |
Genetic control of nortriptyline kinetics in man: a study of relatives of propositi with high plasma concentrations.
Topics: Adolescent; Adult; Aged; Aging; Body Weight; Female; Genetics, Medical; Humans; Male; Middle Aged; N | 1971 |