nortriptyline has been researched along with Apoplexy in 16 studies
Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compared nortriptyline and fluoxetine with placebo in the treatment of depression and in recovery from physical and cognitive impairments after stroke." | 9.09 | Nortriptyline versus fluoxetine in the treatment of depression and in short-term recovery after stroke: a placebo-controlled, double-blind study. ( Castillo, C; Curdue, K; Kopel, T; Kosier, JT; Newman, RM; Petracca, G; Robinson, RG; Schultz, SK; Starkstein, SE, 2000) |
| "During the 1-year follow-up period, and after adjusting for critical confounders including age, intensity of rehabilitation therapy, baseline stroke severity, and baseline Hamilton Depression Rating Scale, patients who received fluoxetine or nortriptyline had significantly greater improvement in modified Rankin Scale scores compared to patients who received placebo (t [156] = -3." | 5.15 | Effect of antidepressants on the course of disability following stroke. ( Adams, HP; Davis, PH; Jang, M; Jorge, RE; Leira, EC; Mikami, K; Robinson, RG, 2011) |
| "The authors randomly assigned nondepressed patients at least 3 months poststroke to receive nortriptyline, fluoxetine, or placebo for 3 months using double-blind methodology." | 5.12 | Risk factors for and correlates of poststroke depression following discontinuation of antidepressants. ( Fiedorowicz, JG; Robinson, RG; Takezawa, K, 2007) |
| "A total of 104 patients were randomly assigned to receive a 12-week double-blind course of nortriptyline, fluoxetine, or placebo early in the recovery period after a stroke." | 5.10 | Mortality and poststroke depression: a placebo-controlled trial of antidepressants. ( Arndt, S; Jorge, RE; Robinson, RG; Starkstein, S, 2003) |
| "This study compared nortriptyline and fluoxetine with placebo in the treatment of depression and in recovery from physical and cognitive impairments after stroke." | 5.09 | Nortriptyline versus fluoxetine in the treatment of depression and in short-term recovery after stroke: a placebo-controlled, double-blind study. ( Castillo, C; Curdue, K; Kopel, T; Kosier, JT; Newman, RM; Petracca, G; Robinson, RG; Schultz, SK; Starkstein, SE, 2000) |
| "Patients with major (n=33) or minor (n=14) depression participated in a double-blind treatment study with nortriptyline or placebo." | 5.09 | Treatment of cognitive impairment after poststroke depression : a double-blind treatment trial. ( Kimura, M; Kosier, JT; Robinson, RG, 2000) |
| "Randomized controlled trials have demonstrated the efficacy of sertraline, citalopram and nortriptyline to treat post-stroke depression." | 4.84 | Antidepressant therapy in post-stroke depression. ( Mizrahi, R; Power, BD; Starkstein, SE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (93.75) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mikami, K | 1 |
| Jorge, RE | 2 |
| Adams, HP | 1 |
| Davis, PH | 1 |
| Leira, EC | 1 |
| Jang, M | 1 |
| Robinson, RG | 9 |
| Arndt, S | 3 |
| Starkstein, S | 1 |
| Hackett, M | 2 |
| Anderson, C | 2 |
| House, A | 2 |
| Dean, CE | 1 |
| Chan, KL | 1 |
| Campayo, A | 1 |
| Moser, DJ | 2 |
| Narushima, K | 2 |
| Paradiso, S | 1 |
| Jorge, R | 1 |
| Fiedorowicz, JG | 1 |
| Takezawa, K | 1 |
| Starkstein, SE | 2 |
| Mizrahi, R | 1 |
| Power, BD | 1 |
| Schultz, SK | 1 |
| Castillo, C | 1 |
| Kopel, T | 1 |
| Kosier, JT | 4 |
| Newman, RM | 1 |
| Curdue, K | 1 |
| Petracca, G | 1 |
| Kimura, M | 1 |
| Audet, AM | 1 |
| Hartman, EE | 1 |
| Franco, K | 1 |
| Malhotra, S | 1 |
| Chemerinski, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction[NCT02386475] | Phase 4 | 39 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nortriptyline and Apoplexy
| Article | Year |
|---|---|
Antidepressant therapy in post-stroke depression.
Topics: Antidepressive Agents; Citalopram; Controlled Clinical Trials as Topic; Depressive Disorder; Humans; | 2008 |
9 trials available for nortriptyline and Apoplexy
| Article | Year |
|---|---|
Effect of antidepressants on the course of disability following stroke.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depre | 2011 |
Mortality and poststroke depression: a placebo-controlled trial of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; | 2003 |
Aggressive behavior in patients with stroke: association with psychopathology and results of antidepressant treatment on aggression.
Topics: Aged; Aggression; Analysis of Variance; Antidepressive Agents, Tricyclic; Depression; Double-Blind M | 2006 |
Effect of antidepressant therapy on executive function after stroke.
Topics: Aged; Antidepressive Agents; Cognition Disorders; Double-Blind Method; Female; Fluoxetine; Humans; M | 2007 |
Risk factors for and correlates of poststroke depression following discontinuation of antidepressants.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Gen | 2007 |
Nortriptyline versus fluoxetine in the treatment of depression and in short-term recovery after stroke: a placebo-controlled, double-blind study.
Topics: Activities of Daily Living; Antidepressive Agents, Tricyclic; Cognition Disorders; Depressive Disord | 2000 |
Treatment of cognitive impairment after poststroke depression : a double-blind treatment trial.
Topics: Affect; Aged; Antidepressive Agents, Tricyclic; Cognition; Cognition Disorders; Depression; Double-B | 2000 |
The effect of remission of poststroke depression on activities of daily living in a double-blind randomized treatment study.
Topics: Activities of Daily Living; Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Doub | 2001 |
Preventing poststroke depression: a 12-week double-blind randomized treatment trial and 21-month follow-up.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; | 2002 |
6 other studies available for nortriptyline and Apoplexy
| Article | Year |
|---|---|
Selective serotonin reuptake inhibitors and the tricyclic antidepressant nortriptyline in the treatment of post stroke depression.
Topics: Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Humans; Nortriptyli | 2004 |
Mortality and poststroke depression.
Topics: Antidepressive Agents; Brain-Derived Neurotrophic Factor; Comorbidity; Depressive Disorder; Fluoxeti | 2004 |
Post-stroke depression impedes recovery.
Topics: Antidepressive Agents, Tricyclic; Depression; Humans; Nortriptyline; Stroke; Stroke Rehabilitation | 2000 |
An 82-year-old woman with mood changes following a stroke, 1 year later.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antidepressive Agents; Depression; Female; Huma | 2001 |
Poststroke depression.
Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Fluoxetine; Humans; Middle Aged; Nortri | 2001 |
Authors should be accurate when describing study design.
Topics: Cognition Disorders; Duplicate Publications as Topic; Humans; Meta-Analysis as Topic; Nortriptyline; | 2001 |