Page last updated: 2024-11-01

nortriptyline and Anxiety Disorders

nortriptyline has been researched along with Anxiety Disorders in 33 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Anxiety Disorders: Persistent and disabling ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"Among 811 adults with moderate-to-severe depression, melancholic, atypical, anxious and anxious-somatizing depression subtypes established at baseline were evaluated as predictors of outcome of treatment with flexible dosage of the SSRI escitalopram or the tricyclic antidepressant nortriptyline."2.76Melancholic, atypical and anxious depression subtypes and outcome of treatment with escitalopram and nortriptyline. ( Aitchison, KJ; Dernovsek, MZ; Farmer, A; Hauser, J; Henigsberg, N; Kalember, P; Maier, W; McGuffin, P; Mendlewicz, J; Mors, O; Placentino, A; Rietschel, M; Souery, D; Uher, R; Zobel, A, 2011)
"Paroxetine-treated subjects received a psychotherapy tailored for traumatic grief."2.69A post hoc comparison of paroxetine and nortriptyline for symptoms of traumatic grief. ( Houck, PR; Jacobs, S; Miller, MD; Prigerson, HG; Reynolds, CF; Shear, MK; Zygmont, M, 1998)
"Although anxiety is associated with Parkinson's disease, anxiety disorders can begin before the onset of motor symptoms, and have been linked to a possible abnormality of dopaminergic, serotonergic, and adrenergic neurons that precedes motor disturbance."2.58Pharmacological interventions for anxiety in Parkinson's disease sufferers. ( Kohsaka, M; Oeda, T; Park, K; Sawada, H; Tomita, S; Umemura, A; Yamamoto, K, 2018)
"It is important to understand both the kinetic and the dynamic implications of dosing TCAs and BZs in the elderly, for whom these drugs are frequently prescribed."2.37Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics. ( Cutler, NR; Narang, PK, 1984)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199017 (51.52)18.7374
1990's9 (27.27)18.2507
2000's5 (15.15)29.6817
2010's2 (6.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sawada, H1
Umemura, A1
Kohsaka, M1
Tomita, S1
Park, K1
Oeda, T1
Yamamoto, K1
Uher, R1
Dernovsek, MZ1
Mors, O1
Hauser, J1
Souery, D1
Zobel, A1
Maier, W1
Henigsberg, N1
Kalember, P1
Rietschel, M1
Placentino, A1
Mendlewicz, J1
Aitchison, KJ1
McGuffin, P1
Farmer, A1
HUGHES, FW1
FORNEY, RB1
SEID, B1
REEVES, JE1
KLINE, NS1
SCHACTER, F1
LANG, HB1
Lenze, EJ1
Mulsant, BH3
Dew, MA1
Shear, MK4
Houck, P1
Pollock, BG1
Reynolds, CF4
Kurpius, MP1
Alexander, B1
Dombrovski, AY1
Blakesley-Ball, RE1
Mazumdar, S2
Houck, PR4
Szanto, K2
Wiesegger, G1
Kienbacher, C1
Pellegrini, E1
Scheidinger, H1
Vesely, C1
Bangerl, W1
Friedrich, M1
Cutler, NR1
Narang, PK1
Valle-Jones, JC3
Craven, JR1
Wallis, TD1
Schiff, AA4
Hyde, C1
Goldberg, D1
Davidson, J1
Linnoila, M1
Raft, D1
Turnbull, CD1
Powell, BJ1
Campbell, JL1
Landon, JF1
Liskow, BI1
Thomas, HM1
Nickel, EJ1
Dale, TM1
Penick, EC1
Samuelson, SD1
Lacoursiere, RB1
Brown, C2
Schulberg, HC2
Madonia, MJ1
Flint, AJ1
Rifat, SL1
Wamboldt, MZ1
Yancey, AG1
Roesler, TA1
Zygmont, M1
Prigerson, HG1
Miller, MD2
Jacobs, S1
Lecrubier, Y1
Swartz, CM1
Guadagno, G1
Walsh, MR2
Dunckley, HG1
Sinclair, JM2
Pacini, L1
Filippini, G1
Brodie, NH1
McGhie, RL1
O'Hara, H1
O'Hara, J1
Rodway, AE1
Maisto, F1
Stein, MB1
Uhde, TW1
Frances, A1
Flaherty, JA1
Sallent Herranz, JA1
Sep-Kowalik, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005461]0 participants Observational1991-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for nortriptyline and Anxiety Disorders

ArticleYear
Pharmacological interventions for anxiety in Parkinson's disease sufferers.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:10

    Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Dopamine; Dopamine Agonists; Humans; Nortriptyl

2018
[Pharmacotherapy of attention-deficit/hyperactivity disorder (ADHD) and comorbid disorders].
    Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater, 2007, Volume: 21, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Antipsychotic Agents; Anxiety Disorders; Atomoxetine Hydrochloride; At

2007
Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Adipose Tissue; Adult; Aged; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorde

1984
Cardiovascular effects of tricyclic antidepressants in childhood asthma: a case series and review.
    Journal of child and adolescent psychopharmacology, 1997,Spring, Volume: 7, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Asthma; B

1997
The impact of comorbidity on the treatment of panic disorder.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 8

    Topics: Agoraphobia; Anxiety Disorders; Comorbidity; Depressive Disorder; Humans; Mental Disorders; Nortript

1998

Trials

14 trials available for nortriptyline and Anxiety Disorders

ArticleYear
Melancholic, atypical and anxious depression subtypes and outcome of treatment with escitalopram and nortriptyline.
    Journal of affective disorders, 2011, Volume: 132, Issue:1-2

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Disorders

2011
Good treatment outcomes in late-life depression with comorbid anxiety.
    Journal of affective disorders, 2003, Volume: 77, Issue:3

    Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Antidepressive Agents, Second-Generation; Antidepressi

2003
Mixed anxiety/depressive illness in general practice. A therapeutic comparison of nomifensine with fluphenazine/nortriptyline.
    Acta psychiatrica Scandinavica, 1983, Volume: 68, Issue:6

    Topics: Adolescent; Adult; Aged; Anxiety Disorders; Depressive Disorder; Double-Blind Method; Drug Combinati

1983
A double-blind, placebo-controlled study of nortriptyline and bromocriptine in male alcoholics subtyped by comorbid psychiatric disorders.
    Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:2

    Topics: Adult; Alcoholism; Antisocial Personality Disorder; Anxiety Disorders; Bromocriptine; Comorbidity; D

1995
Treatment outcomes for primary care patients with major depression and lifetime anxiety disorders.
    The American journal of psychiatry, 1996, Volume: 153, Issue:10

    Topics: Adolescent; Adult; Antidepressive Agents; Anxiety Disorders; Combined Modality Therapy; Comorbidity;

1996
Anxious depression in elderly patients. Response to antidepressant treatment.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1997,Spring, Volume: 5, Issue:2

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Anxiety Disorders; Combined Modality Therapy; Depres

1997
Phenomenology and severity of major depression and comorbid lifetime anxiety disorders in primary medical care practice.
    Anxiety, 1996, Volume: 2, Issue:5

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Anxiety Disorders; Comorbidity; Depressiv

1996
A post hoc comparison of paroxetine and nortriptyline for symptoms of traumatic grief.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:5

    Topics: Adjustment Disorders; Adult; Aged; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive D

1998
Melancholia with onset during treatment with SSRIs.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1998, Volume: 10, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Dis

1998
A test of the concept of "underlying depressive illness" in the treatment of anxiety states.
    Current medical research and opinion, 1976, Volume: 4, Issue:5

    Topics: Adjustment Disorders; Adult; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Drug

1976
[Clinical study with a combination of fluphenazine and nortriptyline in 70 cases of anxiety-depressive neuroses].
    La Clinica terapeutica, 1977, May-31, Volume: 81, Issue:4

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Drug Com

1977
Once daily administration of a fluphenazine/nortriptyline preparation in the treatment of mixed anxiety/depressive states.
    Current medical research and opinion, 1976, Volume: 4, Issue:5

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Drug Adm

1976
Treatment of anxiety/depressive conditions in the elderly: a double-blind comparative study of Motival and amitriptyline.
    Age and ageing, 1975, Volume: 4, Issue:4

    Topics: Aged; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Double-Blind

1975
Triiodothyronine potentiation of tricyclic antidepressant treatment in patients with panic disorder.
    Biological psychiatry, 1990, Dec-15, Volume: 28, Issue:12

    Topics: Adult; Anxiety Disorders; Arousal; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipra

1990

Other Studies

14 other studies available for nortriptyline and Anxiety Disorders

ArticleYear
Delayed audiofeedback (DAF) for induction of anxiety. Effect of nortriptyline, ethanol, or nortriptyline-ethanol combinations on performance with DAF.
    JAMA, 1963, Aug-17, Volume: 185

    Topics: Anxiety; Anxiety Disorders; Ethanol; Humans; Mental Processes; Motor Skills; Nortriptyline

1963
A STUDY OF THE ANTIANXIETY EFFECT OF NORTRIPTYLINE IN UROLOGICAL PATIENTS.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Biomedical Re

1964
NORTRIPTYLINE: A NEW ANTIDEPRESSANT EVALUATED IN A GENERAL MEDICAL PRACTICE.
    Southwestern medicine, 1964, Volume: 45

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Anxiety Disorders; Biomedical Research; Geriatrics; N

1964
NORTRIPTYLINE IN PRIVATE PRACTICE.
    Canadian Psychiatric Association journal, 1965, Volume: 10

    Topics: Antidepressive Agents; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Drug Therapy; No

1965
CLINICAL REPORT ON PARENTERAL NORTRIPTYLINE.
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Antidepressive Agents; Anxiety; Anxiety Disorders; Bipolar Disorder; Depression; Depressive Disorder

1965
Rates of in vivo methylation of desipramine and nortriptyline.
    Pharmacotherapy, 2006, Volume: 26, Issue:4

    Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Disorder; Desipra

2006
Speed of improvement in sleep disturbance and anxiety compared with core mood symptoms during acute treatment of depression in old age.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2006, Volume: 14, Issue:6

    Topics: Aged; Antidepressive Agents, Tricyclic; Anxiety Disorders; Cognitive Behavioral Therapy; Combined Mo

2006
Labelling and drug effects in the treatment of neurotic affective disorders: an experimental investigation.
    Psychological medicine, 1983, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aged; Anxiety Disorders; Depressive Disorder; Diazepam; Double-Blind Method; Fema

1983
MAO inhibition and control of anxiety following amitriptyline therapy. A pilot study.
    Acta psychiatrica Scandinavica, 1981, Volume: 63, Issue:2

    Topics: Adult; Amitriptyline; Anxiety Disorders; Blood Platelets; Female; Humans; Male; Monoamine Oxidase; M

1981
Treatment outcome in suicidal vs. non-suicidal elderly patients.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2001,Summer, Volume: 9, Issue:3

    Topics: Aged; Antidepressive Agents; Anxiety Disorders; Depressive Disorder, Major; Female; Humans; Male; No

2001
[The anxious-depressive syndrome. Polycentric study with the collaboration of 1,048 Italian physicians].
    La Clinica terapeutica, 1977, Jan-15, Volume: 80, Issue:1

    Topics: Adjustment Disorders; Adult; Aged; Anxiety Disorders; Female; Fluphenazine; Humans; Male; Middle Age

1977
Elderly widow develops panic attacks, followed by depression.
    Hospital & community psychiatry, 1989, Volume: 40, Issue:1

    Topics: Aged; Anxiety Disorders; Depressive Disorder; Fear; Female; Humans; Nortriptyline; Panic; Psychother

1989
[Gastrointestinal diseases associated with emotional processes. Personal clinical experience].
    Revista espanola de las enfermedades del aparato digestivo, 1968, Volume: 27, Issue:1

    Topics: Adjustment Disorders; Adult; Aged; Anxiety Disorders; Female; Gastrointestinal Diseases; Humans; Mal

1968
[Effects of dibenzocycloheptadienic derivatives in treatment of depressive syndromes].
    Neurologia, neurochirurgia i psychiatria polska, 1966, Volume: 16, Issue:8

    Topics: Amitriptyline; Anxiety Disorders; Depression; Humans; Nortriptyline; Schizophrenia

1966