Page last updated: 2024-11-01

nortriptyline and ADDH

nortriptyline has been researched along with ADDH in 21 studies

Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.

Research Excerpts

ExcerptRelevanceReference
"While nortriptyline statistically decreased the incidence of nocturnal enuresis during the intervention, the number of enuresis events did not significantly change in the placebo group."5.16Nortriptyline for treating enuresis in ADHD--a randomized double-blind controlled clinical trial. ( Ghanizadeh, A; Haghighat, R, 2012)
" We report on a set of identical twins with a de novo C749G mutation in the FGFR3 gene codon 250 after a pregnancy complicated by prenatal exposure to Nortriptyline."3.75Significant phenotypic variability of Muenke syndrome in identical twins. ( Escobar, LF; Hiett, AK; Marnocha, A, 2009)
" This group of children and adolescents tolerated robust dosing of NT well, with few clinical or cardiovascular adverse events."2.69A controlled study of nortriptyline in children and adolescents with attention deficit hyperactivity disorder. ( Biederman, J; Bostic, JQ; Millstein, R; Polisner, DA; Prince, JB; Spencer, TJ; Wilens, TE, 2000)
" This review focuses on the tolerability, occurrence of adverse events, precautions required to prevent severe adverse events, and essential pharmacological interaction in the treatment of ADHD symptoms by non-stimulants."2.43The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder. ( Banaschewski, T; Heise, CA; Himpel, S; Rothenberger, A, 2005)
"Because in many patients with Tourette's syndrome (TS) the ADHD symptoms are the major source of disability, alternative nonstimulant treatments are needed."1.29Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome. ( Biederman, J; Spencer, T; Steingard, R; Wilens, T, 1993)
"Minimal brain dysfunction is a neurodevelopmental disorder which can be found in nearly 20% of school children."1.26Minimal brain dysfunction/specific learning disability: a clinical approach for the primary physician. ( Levy, HB, 1976)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's10 (47.62)18.2507
2000's4 (19.05)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bastiaens, L1
Scott, O1
Galus, J1
Escobar, LF1
Hiett, AK1
Marnocha, A1
Ghanizadeh, A1
Haghighat, R1
Himpel, S1
Banaschewski, T1
Heise, CA1
Rothenberger, A1
Wiesegger, G1
Kienbacher, C1
Pellegrini, E1
Scheidinger, H1
Vesely, C1
Bangerl, W1
Friedrich, M1
Alderton, HR1
Shader, RI1
Oesterheld, JR1
Wilens, TE5
Biederman, J7
Mick, E1
Spencer, TJ3
Chapman, NA1
Spencer, T4
Wilens, T2
Steingard, R3
Geist, D1
Geist, DE2
Guardiola, A1
Terra, AR1
Pereira, KR1
Rotta, NT1
Prince, JB1
Millstein, R1
Polisner, DA1
Bostic, JQ1
Collis, P1
Levy, HB1
Saul, RC1
Omenn, GS1
Motulsky, AG1
Haddock, ST1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Motivational Interviewing to Reduce Substance Use Among Depression Patients[NCT02420561]307 participants (Actual)Interventional2010-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for nortriptyline and ADDH

ArticleYear
The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Antidepressive Agents, Tricyclic; Atomoxetine Hydrochloride; Atten

2005
[Pharmacotherapy of attention-deficit/hyperactivity disorder (ADHD) and comorbid disorders].
    Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater, 2007, Volume: 21, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Antipsychotic Agents; Anxiety Disorders; Atomoxetine Hydrochloride; At

2007
Tricyclic medication in children and the QT interval: case report and discussion.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1995, Volume: 40, Issue:6

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Chil

1995
Editorial: Pharmacogenetics and mental disease.
    Psychological medicine, 1974, Volume: 4, Issue:2

    Topics: Acetylation; Adjuvants, Anesthesia; Adult; Anticonvulsants; Antidepressive Agents; Attention Deficit

1974

Trials

3 trials available for nortriptyline and ADDH

ArticleYear
Nortriptyline for treating enuresis in ADHD--a randomized double-blind controlled clinical trial.
    Pediatric nephrology (Berlin, Germany), 2012, Volume: 27, Issue:11

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Attention Deficit Disorder with Hyperactivity; Central Ner

2012
[Use of drugs in attention deficit hyperactivity disorders].
    Arquivos de neuro-psiquiatria, 1997, Volume: 55, Issue:3B

    Topics: Analysis of Variance; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivit

1997
A controlled study of nortriptyline in children and adolescents with attention deficit hyperactivity disorder.
    Journal of child and adolescent psychopharmacology, 2000,Fall, Volume: 10, Issue:3

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child;

2000

Other Studies

14 other studies available for nortriptyline and ADDH

ArticleYear
Treatment of Adult ADHD without Stimulants: Effectiveness in A Dually Diagnosed Correctional Population.
    The Psychiatric quarterly, 2019, Volume: 90, Issue:1

    Topics: Adrenergic Agents; Adult; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity;

2019
Significant phenotypic variability of Muenke syndrome in identical twins.
    American journal of medical genetics. Part A, 2009, Volume: 149A, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Amino Acid Sequence; Attention Deficit

2009
Case 6: a free solution.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:4

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Drug In

1995
A systematic assessment of tricyclic antidepressants in the treatment of adult attention-deficit hyperactivity disorder.
    The Journal of nervous and mental disease, 1995, Volume: 183, Issue:1

    Topics: Adult; Age Factors; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Attention Deficit Disord

1995
Safety of clonidine and nortriptyline.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1994, Volume: 33, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Drug Therapy, Combinati

1994
Nortriptyline treatment of children with attention-deficit hyperactivity disorder and tic disorder or Tourette's syndrome.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1993, Volume: 32, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comorbidity; Family Hea

1993
Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1993, Volume: 32, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Bupropion; Child; Clonidine; Desipramine; Female; Hum

1993
A retrospective study of serum levels and electrocardiographic effects of nortriptyline in children and adolescents.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1993, Volume: 32, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child, P

1993
Nortriptyline in the treatment of ADHD: a chart review of 58 cases.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1993, Volume: 32, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Female; Humans; Male; Nortriptylin

1993
Case study: adverse effects of smoking marijuana while receiving tricyclic antidepressants.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1997, Volume: 36, Issue:1

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Drug In

1997
Does minimal brain dysfunction persist into adulthood?
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Apr-01, Volume: 53, Issue:13

    Topics: Attention Deficit Disorder with Hyperactivity; Humans; Nortriptyline

1978
Minimal brain dysfunction/specific learning disability: a clinical approach for the primary physician.
    Southern medical journal, 1976, Volume: 69, Issue:5

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Dextroamphetamine; F

1976
Nortriptyline in attention deficit disorder.
    Clinical neuropharmacology, 1985, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Child; Female; Humans; Male; Nortr

1985
Usefulness of methylphenidate.
    The New England journal of medicine, 1972, Feb-17, Volume: 286, Issue:7

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chronic; Child; Child Behav

1972