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normetanephrine and Substance Withdrawal Syndrome

normetanephrine has been researched along with Substance Withdrawal Syndrome in 9 studies

Normetanephrine: A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.

Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Research Excerpts

ExcerptRelevanceReference
"In this study, we investigated whether morphine dependence was inhibited by phosphodiesterase (PDE) 4 inhibitors rolipram and diazepam, since a role for the cyclic AMP systems in the development of morphine dependence was reported."3.74Phosphodiesterase 4 inhibitors, rolipram and diazepam block the adaptive changes observed during morphine withdrawal in the heart. ( González-Cuello, A; Hernández, J; Laorden, ML; Sánchez, L; Teresa Castells, M; Victoria Milanés, M, 2007)
"Abrupt withdrawal of the centrally-acting antihypertensive agent, clonidine, is associated with a high incidence of rebound hypertension and tachycardia, with symptoms of sympathetic overactivity and increased catecholamine excretion."3.67Regimen for the control of blood pressure and symptoms during clonidine withdrawal. ( Campbell, BC; Reid, JL, 1985)
"Morphine withdrawal was precipitated on day 8 by an injection of naloxone (2 mg/kg, s."1.35Tyrosine hydroxylase phosphorylation after naloxone-induced morphine withdrawal in the left ventricle. ( Almela, P; Luisa Laorden, M; Victoria Milanés, M, 2009)
"Morphine withdrawal was precipitated by administration of naloxone (5 mg/kg subcutaneously) on day 8."1.32Changes in c-fos expression in the rat heart during morphine withdrawal. Involvement of alpha2-adrenoceptors. ( Aviles, M; González-Cuello, A; Laorden, ML; Milanés, MV, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Almela, P1
Victoria Milanés, M2
Luisa Laorden, M1
Martínez, MD1
Milanés, MV2
Laorden, ML3
González-Cuello, A2
Aviles, M1
Sánchez, L1
Hernández, J1
Teresa Castells, M1
Martin, PR1
Ebert, MH1
Gordon, EK1
Weingartner, H1
Kopin, IJ1
De Leon-Jones, FA1
Davis, JM1
Inwang, EE1
Dekirmenjian, H1
Campbell, BC1
Reid, JL1
Tonge, SR1
Weil-Malherbe, H1
Smith, ER1
Eisenman, AJ1
Fraser, HF1

Other Studies

9 other studies available for normetanephrine and Substance Withdrawal Syndrome

ArticleYear
Tyrosine hydroxylase phosphorylation after naloxone-induced morphine withdrawal in the left ventricle.
    Basic research in cardiology, 2009, Volume: 104, Issue:4

    Topics: Animals; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP

2009
Implication of the signal transduction pathways in the enhancement of noradrenaline turnover induced by morphine withdrawal in the heart.
    European journal of pharmacology, 2003, Jun-20, Volume: 471, Issue:2

    Topics: Animals; Calcium Channels, L-Type; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Drug Com

2003
Changes in c-fos expression in the rat heart during morphine withdrawal. Involvement of alpha2-adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Blotting, Western; Body Weight; Drug Administratio

2004
Phosphodiesterase 4 inhibitors, rolipram and diazepam block the adaptive changes observed during morphine withdrawal in the heart.
    European journal of pharmacology, 2007, Sep-10, Volume: 570, Issue:1-3

    Topics: Animals; Cyclic AMP; Cyclic GMP; Diazepam; Male; Morphine Dependence; Myocardium; Norepinephrine; No

2007
Catecholamine metabolism during clonidine withdrawal.
    Psychopharmacology, 1984, Volume: 84, Issue:1

    Topics: Aged; Catecholamines; Clonidine; Epinephrine; Female; Heart Rate; Humans; Male; Memory; Methoxyhydro

1984
Excretion of catecholamine metabolites during methadone maintenance and withdrawal.
    Archives of general psychiatry, 1983, Volume: 40, Issue:8

    Topics: Adult; Epinephrine; Female; Heroin Dependence; Humans; Male; Metanephrine; Methadone; Methoxyhydroxy

1983
Regimen for the control of blood pressure and symptoms during clonidine withdrawal.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:4

    Topics: Adult; Aged; Atenolol; Blood Pressure; Chlordiazepoxide; Clonidine; Female; Heart Rate; Humans; Hype

1985
Noradrenaline and 5-hydroxytryptamine metabolism in six areas of rat brain during post-amphethamine depression.
    Psychopharmacologia, 1974, Volume: 38, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Depression; Depression, Chemical; Dextroamphetamine; Fluorometry;

1974
Plasma catecholamine levels and urinary excretion of catecholamines and metabolites in two human subjects during a cycle of morphine addiction and withdrawal.
    Biochemical pharmacology, 1965, Volume: 14, Issue:11

    Topics: Blood; Catecholamines; Dopamine; Epinephrine; Humans; Male; Morphine Dependence; Norepinephrine; Nor

1965