normetanephrine has been researched along with Parkinson Disease in 6 studies
Normetanephrine: A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levodopa induced an increase of about 400 fold in urinary DA; DOPAC was increased about 300 fold, 3-MT only about 70 fold, but HVA about 300 fold." | 1.25 | Urinary excretion of monoamines and their metabolites in patients with Parkinson's disease. Response to long-term treatment with levodopa alone or in combination with a dopa decarboxylase inhibitor and clinical correlations. ( Rinne, UK; Siirtola, T; Sonninen, V, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eisenhofer, G | 2 |
| Brown, S | 1 |
| Peitzsch, M | 1 |
| Pelzel, D | 1 |
| Lattke, P | 1 |
| Glöckner, S | 1 |
| Stell, A | 1 |
| Prejbisz, A | 1 |
| Fassnacht, M | 1 |
| Beuschlein, F | 1 |
| Januszewicz, A | 1 |
| Siegert, G | 1 |
| Reichmann, H | 1 |
| Collier, A | 1 |
| Ghosh, S | 1 |
| Breckenridge, A | 1 |
| Perry, CG | 1 |
| Freel, EM | 1 |
| Davidson, DF | 2 |
| Goldstein, DS | 1 |
| Holmes, C | 1 |
| Sharabi, Y | 1 |
| Brentzel, S | 1 |
| Grosset, K | 1 |
| Grosset, D | 1 |
| Siirtola, T | 1 |
| Sonninen, V | 1 |
| Rinne, UK | 1 |
| Routh, JI | 1 |
| Bannow, RE | 1 |
| Fincham, RW | 1 |
| Stoll, JL | 1 |
1 trial available for normetanephrine and Parkinson Disease
| Article | Year |
|---|---|
Parkinson's disease: the effect of L-dopa therapy on urinary free catecholamines and metabolites.
Topics: Adolescent; Adult; Aged; Antiparkinson Agents; Catecholamines; Creatinine; Dopamine; Female; Homovan | 2007 |
5 other studies available for normetanephrine and Parkinson Disease
| Article | Year |
|---|---|
Levodopa therapy in Parkinson's disease: influence on liquid chromatographic tandem mass spectrometric-based measurements of plasma and urinary normetanephrine, metanephrine and methoxytyramine.
Topics: Aged; Aged, 80 and over; Chromatography, Liquid; Dopamine; Epinephrine; Female; Humans; Levodopa; Ma | 2014 |
A phaeochromocytoma occurring in a patient with Parkinson's disease on L-dopa therapy: a diagnostic challenge.
Topics: Adrenal Gland Neoplasms; Antiparkinson Agents; Creatinine; Humans; Levodopa; Male; Metanephrine; Mid | 2012 |
Plasma levels of catechols and metanephrines in neurogenic orthostatic hypotension.
Topics: Adrenal Medulla; Aged; Autonomic Nervous System Diseases; Catechols; Epinephrine; Female; Heart Cond | 2003 |
Urinary excretion of monoamines and their metabolites in patients with Parkinson's disease. Response to long-term treatment with levodopa alone or in combination with a dopa decarboxylase inhibitor and clinical correlations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Benserazide; Biogenic Amines; Dopamine; Female; Homovanillic Acid; H | 1975 |
Excretion of L-dopa and its metabolites in urine of Parkinson's disease patients receiving L-dopa therapy.
Topics: Aged; Aluminum; Chromatography; Chromatography, Ion Exchange; Colorimetry; Dihydroxyphenylalanine; D | 1971 |