normetanephrine has been researched along with Morphine Abuse in 4 studies
Normetanephrine: A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with yohimbine (alpha(2)-adrenoceptor) or prazosin (alpha(1)-adrenoceptor) 15 min prior to naloxone administration attenuated some of the behavioural signs of morphine withdrawal." | 5.31 | Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors. ( Laorden, ML; Milanés, MV, 2000) |
| "In this study, we investigated whether morphine dependence was inhibited by phosphodiesterase (PDE) 4 inhibitors rolipram and diazepam, since a role for the cyclic AMP systems in the development of morphine dependence was reported." | 3.74 | Phosphodiesterase 4 inhibitors, rolipram and diazepam block the adaptive changes observed during morphine withdrawal in the heart. ( González-Cuello, A; Hernández, J; Laorden, ML; Sánchez, L; Teresa Castells, M; Victoria Milanés, M, 2007) |
| "Pretreatment with yohimbine (alpha(2)-adrenoceptor) or prazosin (alpha(1)-adrenoceptor) 15 min prior to naloxone administration attenuated some of the behavioural signs of morphine withdrawal." | 1.31 | Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors. ( Laorden, ML; Milanés, MV, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martínez, MD | 1 |
| Milanés, MV | 2 |
| Laorden, ML | 3 |
| González-Cuello, A | 1 |
| Sánchez, L | 1 |
| Hernández, J | 1 |
| Teresa Castells, M | 1 |
| Victoria Milanés, M | 1 |
| Weil-Malherbe, H | 1 |
| Smith, ER | 1 |
| Eisenman, AJ | 1 |
| Fraser, HF | 1 |
4 other studies available for normetanephrine and Morphine Abuse
| Article | Year |
|---|---|
Implication of the signal transduction pathways in the enhancement of noradrenaline turnover induced by morphine withdrawal in the heart.
Topics: Animals; Calcium Channels, L-Type; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Drug Com | 2003 |
Phosphodiesterase 4 inhibitors, rolipram and diazepam block the adaptive changes observed during morphine withdrawal in the heart.
Topics: Animals; Cyclic AMP; Cyclic GMP; Diazepam; Male; Morphine Dependence; Myocardium; Norepinephrine; No | 2007 |
Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Catechola | 2000 |
Plasma catecholamine levels and urinary excretion of catecholamines and metabolites in two human subjects during a cycle of morphine addiction and withdrawal.
Topics: Blood; Catecholamines; Dopamine; Epinephrine; Humans; Male; Morphine Dependence; Norepinephrine; Nor | 1965 |