noribogaine and Parkinsonian-Disorders
noribogaine has been researched along with Parkinsonian-Disorders* in 1 studies
Other Studies
1 other study(ies) available for noribogaine and Parkinsonian-Disorders
Article | Year |
---|---|
Pharmacochaperoning in a
Point mutations in the gene encoding the human dopamine transporter (hDAT, SLC6A3) cause a syndrome of infantile/juvenile dystonia and parkinsonism. To unravel the molecular mechanism underlying these disorders and investigate possible pharmacological therapies, here we examined 13 disease-causing DAT mutants that were retained in the endoplasmic reticulum when heterologously expressed in HEK293 cells. In three of these mutants, Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Drosophila melanogaster; Humans; Ibogaine; Male; Mutation; Parkinsonian Disorders; Sulfonamides; Synaptic Transmission | 2017 |