noribogaine and Parkinsonian-Disorders

noribogaine has been researched along with Parkinsonian-Disorders* in 1 studies

Other Studies

1 other study(ies) available for noribogaine and Parkinsonian-Disorders

ArticleYear
Pharmacochaperoning in a
    The Journal of biological chemistry, 2017, 11-24, Volume: 292, Issue:47

    Point mutations in the gene encoding the human dopamine transporter (hDAT, SLC6A3) cause a syndrome of infantile/juvenile dystonia and parkinsonism. To unravel the molecular mechanism underlying these disorders and investigate possible pharmacological therapies, here we examined 13 disease-causing DAT mutants that were retained in the endoplasmic reticulum when heterologously expressed in HEK293 cells. In three of these mutants,

    Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Drosophila melanogaster; Humans; Ibogaine; Male; Mutation; Parkinsonian Disorders; Sulfonamides; Synaptic Transmission

2017
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